Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Heba Z. Abid"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Identification of structural variants (SVs) breakpoints is important in studying mutations, mutagenic causes, and functional impacts. Next-generation sequencing and whole-genome optical mapping are extensively used in SV discovery and charac
Externí odkaz:
https://doaj.org/article/94ef061e8b3d4ae6974592d3b2c5bf9c
Autor:
Heba Z. Abid, Jennifer McCaffrey, Kaitlin Raseley, Eleanor Young, Katy Lassahn, Dharma Varapula, Harold Riethman, Ming Xiao
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-17 (2020)
Abstract Background Telomeric DNA is typically comprised of G-rich tandem repeat motifs and maintained by telomerase (Greider CW, Blackburn EH; Cell 51:887–898; 1987). In eukaryotes lacking telomerase, a variety of DNA repair and DNA recombination
Externí odkaz:
https://doaj.org/article/044b46efdc734eb7ac02eca66ee0b077
Autor:
Ming Xiao, Lahari Uppuluri, Beverly S. Emanuel, Donna M. McDonald-McGinn, Daniel E. McGinn, Deanne Taylor, Benjamin A. Silva, T. Blaine Crowley, Michael Xie, Heba Z. Abid, Bernice E. Morrow, Steven Pastor, Elaine H. Zackai, Oanh Tran, Alice Bailey, Eleanor Young, Danielle Carrado, Andrea Jin
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
The most prevalent microdeletion in humans occurs at 22q11.2, a region rich in chromosome-specific low copy repeats (LCR22s). The structure of this region has defied elucidation due to its size, regional complexity, and haplotype diversity, and is no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32c1b75f551f3d9ba05ded3008e83778
http://link.springer.com/article/10.1038/s41598-020-69134-4
http://link.springer.com/article/10.1038/s41598-020-69134-4
Publikováno v:
Scientific reports. 12(1)
Identification of structural variants (SVs) breakpoints is important in studying mutations, mutagenic causes, and functional impacts. Next-generation sequencing and whole-genome optical mapping are extensively used in SV discovery and characterizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99f6549158e619a3d00752c9806bab8a
https://pubmed.ncbi.nlm.nih.gov/35444207
https://pubmed.ncbi.nlm.nih.gov/35444207
Autor:
Dharma Varapula, Heba Z. Abid, Joshua Chang Mell, Ming Xiao, Kaitlin Raseley, Danielle Piazza, Hung-Yi Wang, Eleanor Young, Jennifer McCaffrey
Publikováno v:
Nucleic Acids Research
Whole-genome mapping technologies have been developed as a complementary tool to provide scaffolds for genome assembly and structural variation analysis (1,2). We recently introduced a novel DNA labeling strategy based on a CRISPR–Cas9 genome editi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed4b32a140516fec0056a25afbb121a6
https://pubmed.ncbi.nlm.nih.gov/33231685
https://pubmed.ncbi.nlm.nih.gov/33231685
Autor:
Katy Lassahn, Heba Z. Abid, Jennifer McCaffrey, Harold Riethman, Ming Xiao, Dharma Varapula, Eleanor Young, Kaitlin Raseley
Publikováno v:
BMC Genomics
BMC Genomics, Vol 21, Iss 1, Pp 1-17 (2020)
BMC Genomics, Vol 21, Iss 1, Pp 1-17 (2020)
Background Telomeric DNA is typically comprised of G-rich tandem repeat motifs and maintained by telomerase (Greider CW, Blackburn EH; Cell 51:887–898; 1987). In eukaryotes lacking telomerase, a variety of DNA repair and DNA recombination based pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eb57a619c7fcf74021045d0a5e875b8
http://europepmc.org/articles/PMC7364475
http://europepmc.org/articles/PMC7364475
Publikováno v:
PLoS genetics, vol 16, iss 1
PLoS Genetics
PLoS Genetics, Vol 16, Iss 1, p e1008347 (2020)
PLoS Genetics
PLoS Genetics, Vol 16, Iss 1, p e1008347 (2020)
Detailed comprehensive knowledge of the structures of individual long-range telomere-terminal haplotypes are needed to understand their impact on telomere function, and to delineate the population structure and evolution of subtelomere regions. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b839958f7a194ffaacc754c1d073c0e8
https://doi.org/10.1371/journal.pgen.1008347
https://doi.org/10.1371/journal.pgen.1008347
Publikováno v:
PLoS Genetics, Vol 16, Iss 1, p e1008347 (2020)
Detailed comprehensive knowledge of the structures of individual long-range telomere-terminal haplotypes are needed to understand their impact on telomere function, and to delineate the population structure and evolution of subtelomere regions. Howev
Externí odkaz:
https://doaj.org/article/5c763bad0da54f7cb953215ad0f77387