Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Heba E. Hashem"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Computer-aided drug design has been employed to get the medicinal effects against Corona virus from different pyridine derivatives after synthesizing the new compounds. Additionally, various computational studies are also employed between th
Externí odkaz:
https://doaj.org/article/0276e62e1e9c41c4bba368b5c549ea5c
Publikováno v:
Journal of Scientific Research in Science, Vol 39, Iss 1, Pp 83-103 (2022)
Reactions of 4H-3,1-benzoxazin-4-one 3 with various nitrogen nucleophiles; sodium azide, hydroxylamine hydrochloride, ammonium acetate, and formamide afforded new N-heterocyclic compounds 4-7. The synthesized quinazolinone derivative 7 was used as a
Externí odkaz:
https://doaj.org/article/763e21741e5c4732b8d2430c89b0d438
Publikováno v:
BMC Pharmacology and Toxicology, Vol 23, Iss 1, Pp 1-9 (2022)
Abstract Background The gut microbiome, a new organ of the body, can potentially alter the pharmacokinetics of orally administered drugs through microbial enzymes. However, absorption of orally administered non-antibiotic drugs by the gut microbiome,
Externí odkaz:
https://doaj.org/article/a961e0814dda463baefcef1066cae932
Autor:
Amal Ferchichi, Jawher Makhlouf, Youness El Bakri, Kandasamy Saravanan, Arto Valkonen, Heba E. Hashem, Sajjad Ahmad, Wajda Smirani
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract The cobalt (II) complexes have been synthesized from the reaction of the cationic entities (3,4-dimethylaniline (1) and histamine (2)) with metallic salt CoCl2⋅6H2O and thiocyanate ion (SCN−) as a ligand in H2O/ethanolic solution and pro
Externí odkaz:
https://doaj.org/article/fcb467769d7648a383647d8adc63e8fa
Autor:
Heba E. Hashem, Abd El-Galil E. Amr, Abdulrahman A. Almehizia, Ahmed M. Naglah, Benson M. Kariuki, Heba A. Eassa, Eman S. Nossier
Publikováno v:
Molecules, Vol 28, Iss 21, p 7252 (2023)
The strategic planning of this study is based upon using the nanoformulation method to prepare nanoparticles 4-SLNs and 4-LPHNPs of the previously prepared 4,5-diphenyl-1H-pyrazolo[3,4-c]pyridazin-3-amine (4) after confirming its structure with singl
Externí odkaz:
https://doaj.org/article/1737292098e947cc901c6e1b9e251cc0
Publikováno v:
ACS Omega, Vol 7, Iss 8, Pp 7155-7171 (2022)
Externí odkaz:
https://doaj.org/article/0983faeeab5c478ab893687b51450311
Autor:
Heba E. Hashem, Youness El Bakri
Publikováno v:
Arabian Journal of Chemistry, Vol 14, Iss 11, Pp 103418- (2021)
Benzimidazole, a benzene-fused heterocyclic compound, has acquired significant attention in the field of contemporary medicinal chemistry because of its wide array of pharmacological activities. Nitrogen containing heterocyclic compounds are part of
Externí odkaz:
https://doaj.org/article/ef608dd4a54649b8962e3d8191a0e074
Autor:
Heba E. Hashem, Rania M. Abdel Halim, Sherin A. El Masry, Amira M. Mokhtar, Noureldin M. Abdelaal
Publikováno v:
International Journal of Microbiology, Vol 2020 (2020)
Background. Neonatal septicemia is a critical medical situation; current conventional laboratory methods still have many limitations and diagnostic obstacles. For this purpose, last decades have witnessed a challenge between the battery of sepsis bio
Externí odkaz:
https://doaj.org/article/87fa62f4c9834104b6ee900d2fb5805f
Autor:
Heba E. Hashem, Ahmed M. Abo-Bakr
Publikováno v:
Heteroatom Chemistry, Vol 2019 (2019)
1,2,4-Triazine and 1,2,5-oxadiazine derivatives 2–12 were obtained from treated 1,3-oxazolone (1) with phenyl hydrazine or hydroxylamine hydrochloride. Chlorotriazine derivative 3 undergoing condensation reactions with different reagents produced n
Externí odkaz:
https://doaj.org/article/6d74cf072d594c85897cf51afd1ebdeb
Publikováno v:
Molecules, Vol 25, Iss 12, p 2766 (2020)
To develop new antimicrobial agents, a series of novel thiourea derivatives incorporated with different moieties 2–13 was designed and synthesized and their biological activities were evaluated. Compounds 7a, 7b and 8 exhibited excellent antimicrob
Externí odkaz:
https://doaj.org/article/f13401155ad84bfd869c33f9f527fcec