Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Heba A. Alkhatabi"'
Publikováno v:
Pharmaceuticals, Vol 17, Iss 9, p 1120 (2024)
Sirtuin 2 (SIRT2), an NAD+-dependent deacetylase, is crucial for regulating vital physiological processes, including aging, DNA repair, and cell cycle progression. Its abnormal activity is linked to diseases such as Parkinson’s disease, cancer, and
Externí odkaz:
https://doaj.org/article/13180136154d4c62b7d50fe26155000d
Autor:
Walaa F. Alsanie, Sherin Abdelrahman, Majid Alhomrani, Ahmed Gaber, Hamza Habeeballah, Heba A. Alkhatabi, Raed I. Felimban, Charlotte A. E. Hauser, Hossam H. Tayeb, Abdulhakeem S. Alamri, Bassem M. Raafat, Sirajudheen Anwar, Khaled A. Alswat, Yusuf S. Althobaiti, Yousif A. Asiri
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Gabapentin is widely prescribed as an off-label drug for the treatment of various diseases, including drug and alcohol addiction. Approximately 83–95% of the usage of gabapentin is off-label, accounting for more than 90% of its sales in
Externí odkaz:
https://doaj.org/article/6e20f73c116b4315b2d20531ccfed413
Autor:
Walaa F. Alsanie, Sherin Abdelrahman, Raed I. Felimban, Heba A. Alkhatabi, Ahmed Gaber, Ebtisam Abdulah Alosimi, Majid Alhomrani, Hamza Habeeballah, Charlotte A. E. Hauser, Abdulhakeem S. Alamri, Aiysha Althobaiti, Abdulaziz Alsharif, Ahmed S. Alzahrani, Mohammad S. Al-Ghamdi, Bassem M. Raafat, Khaled A. Alswat, Yusuf S. Althobaiti, Yousif A. Asiri
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5668 (2023)
Methamphetamine, a highly addictive central nervous system (CNS) stimulant, is used worldwide as an anorexiant and attention enhancer. Methamphetamine use during pregnancy, even at therapeutic doses, may harm fetal development. Here, we examined whet
Externí odkaz:
https://doaj.org/article/f76f07a47a1b49b28575ad7e2a94e9b5
Autor:
Walaa F. Alsanie, Sherin Abdelrahman, Majid Alhomrani, Ahmed Gaber, Ebtisam Abdulah Alosimi, Hamza Habeeballah, Heba A. Alkhatabi, Raed I. Felimban, Charlotte A. E. Hauser, Hossam H. Tayeb, Abdulhakeem S. Alamri, Abdulwahab Alamri, Bassem M. Raafat, Khaled A. Alswat, Yusuf S. Althobaiti, Yousif A. Asiri
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12352 (2022)
The effects of second-generation antipsychotics on prenatal neurodevelopment, apoptotic neurodegeneration, and postnatal developmental delays have been poorly investigated. Even at standard doses, the use of quetiapine fumarate (QEPF) in pregnant wom
Externí odkaz:
https://doaj.org/article/8d3807aded414ecebb6e76494a16b120
Autor:
Abdulhakeem S. Alamri, Majid Alhomrani, Walaa F. Alsanie, Hussain Alyami, Sonam Shakya, Hamza Habeeballah, Osama Abdulaziz, Abdulwahab Alamri, Heba A. Alkhatabi, Raed I. Felimban, Abdulhameed Abdullah Alhabeeb, Moamen S. Refat, Ahmed Gaber
Publikováno v:
Applied Sciences, Vol 12, Iss 19, p 10130 (2022)
The drug barbital (Bar) has a strong sedative–hypnotic effect. The intermolecular charge transfer compounds associated with the chemical reactions between Bar and some π acceptors, such as 2,6-dibromoquinone-4-chloroimide (DBQ), tetracyanoquinodim
Externí odkaz:
https://doaj.org/article/f2fe4cef46c54653abbf0e11a4179352
Autor:
Ahmed Gaber, Walaa F. Alsanie, Majid Alhomrani, Abdulhakeem S. Alamri, Hussain Alyami, Sonam Shakya, Hamza Habeeballah, Heba A. Alkhatabi, Raed I. Felimban, Abdulwahab Alamri, Abdulhameed Abdullah Alhabeeb, Bassem M. Raafat, Moamen S. Refat
Publikováno v:
Molecules, Vol 27, Iss 18, p 5883 (2022)
Poor mood, lack of pleasure, reduced focus, remorse, unpleasant thoughts, and sleep difficulties are all symptoms of depression. The only approved treatment for children and adolescents with major depressive disorder (MDD) is fluoxetine hydrochloride
Externí odkaz:
https://doaj.org/article/e7d9fe7d36204edeb480f0cebae08238
Autor:
Abdulhakeem S. Alamri, Majid Alhomrani, Walaa F. Alsanie, Hussain Alyami, Sonam Shakya, Hamza Habeeballah, Abdulwahab Alamri, Omar Alzahrani, Ahmed S. Alzahrani, Heba A. Alkhatabi, Raed I. Felimban, Abdulhameed Abdullah Alhabeeb, Bassem M. Raafat, Moamen S. Refat, Ahmed Gaber
Publikováno v:
Molecules, Vol 27, Iss 10, p 3295 (2022)
Haloperidol (HPL) is a typical antipsychotic drug used to treat acute psychotic conditions, delirium, and schizophrenia. Solid charge transfer (CT) products of HPL with 7,7,8,8-tetracyanoquinodimethane (TCNQ) and picric acid (PA) have not been report
Externí odkaz:
https://doaj.org/article/97d551b90f6f4cd8a35ca65ffd2ba918
Autor:
Walaa F. Alsanie, Abdulhakeem S. Alamri, Hussain Alyami, Majid Alhomrani, Sonam Shakya, Hamza Habeeballah, Heba A. Alkhatabi, Raed I. Felimban, Ahmed S. Alzahrani, Abdulhameed Abdullah Alhabeeb, Bassem M. Raafat, Moamen S. Refat, Ahmed Gaber
Publikováno v:
Molecules, Vol 27, Iss 10, p 3290 (2022)
The charge transfer interactions between the seproxetine (SRX) donor and π-electron acceptors [picric acid (PA), dinitrobenzene (DNB), p-nitrobenzoic acid (p-NBA), 2,6-dichloroquinone-4-chloroimide (DCQ), 2,6-dibromoquinone-4-chloroimide (DBQ), and
Externí odkaz:
https://doaj.org/article/a2a3d460626c42a89b13352055a9905e
Autor:
Walaa F. Alsanie, Majid Alhomrani, Ahmed Gaber, Hamza Habeeballah, Heba A. Alkhatabi, Raed I. Felimban, Sherin Abdelrahman, Charlotte A. E. Hauser, Adeel G. Chaudhary, Abdulhakeem S. Alamri, Bassem M. Raafat, Abdulwahab Alamri, Sirajudheen Anwar, Khaled A. Alswat, Yusuf S. Althobaiti, Yousif A. Asiri
Publikováno v:
Cells, Vol 11, Iss 5, p 852 (2022)
Pregabalin is widely used as a treatment for multiple neurological disorders; however, it has been reported to have the potential for misuse. Due to a lack of safety studies in pregnancy, pregabalin is considered the last treatment option for various
Externí odkaz:
https://doaj.org/article/7fd0e3a0ad94482a83114eae6dacc38e
Autor:
Majid Alhomrani, Walaa F. Alsanie, Abdulhakeem S. Alamri, Hussain Alyami, Hamza Habeeballah, Heba A. Alkhatabi, Raed I. Felimban, John M. Haynes, Sonam Shakya, Bassem M. Raafat, Moamen S. Refat, Ahmed Gaber
Publikováno v:
Pharmaceuticals, Vol 15, Iss 3, p 285 (2022)
The aim of this study was to assess the utility of inexpensive techniques in evaluating the interactions of risperidone (Ris) with different traditional π-acceptors, with subsequent application of the findings into a Ris pharmaceutical formulation w
Externí odkaz:
https://doaj.org/article/3e0911d7d3274393919fbe45fa1039cd