Coenzyme Q10, Ageing and the Nervous System: An Overview

Autor: Mantle, D, Heaton, RA, Hargreaves, IP

Publikováno v: ANTIOXIDANTS
Antioxidants
Antioxidants, Vol 11, Iss 2, p 2 (2022)

The ageing brain is characterised by changes at the physical, histological, biochemical and physiological levels. This ageing process is associated with an increased risk of developing a number of neurological disorders, notably Alzheimer’s disease

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Biallelic variants in coenzyme Q10 biosynthesis pathway genes cause a retinitis pigmentosa phenotype.

Autor: Jurkute N; Moorfields Eye Hospital NHS Foundation Trust, London, UK. n.jurkute@nhs.net.; Institute of Ophthalmology, University College London, London, UK. n.jurkute@nhs.net., Cancellieri F; Institute of Molecular and Clinical Ophthalmology Basel (IOB), Basel, Switzerland.; Department of Ophthalmology, University of Basel, Basel, Switzerland., Pohl L; University Eye Hospital, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany., Li CHZ; Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands.; Department of Ophthalmology, Radboud University Medical Center, Nijmegen, the Netherlands., Heaton RA; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores, Liverpool, UK., Reurink J; Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands.; Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands., Bellingham J; Institute of Ophthalmology, University College London, London, UK., Quinodoz M; Institute of Molecular and Clinical Ophthalmology Basel (IOB), Basel, Switzerland.; Department of Ophthalmology, University of Basel, Basel, Switzerland.; Department of Genetics and Genome Biology, University of Leicester, Leicester, UK., Yioti G; University of Ioannina Medical School, Ioannina, Greece., Stefaniotou M; University of Ioannina Medical School, Ioannina, Greece., Weener M; Oftalmic Clinical Research Organization, Moscow, Russia., Zuleger T; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany., Haack TB; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany.; Centre for Rare Diseases, University of Tübingen, Tübingen, Germany., Stingl K; University Eye Hospital, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.; Centre for Rare Diseases, University of Tübingen, Tübingen, Germany., Hoyng CB; Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands.; Department of Ophthalmology, Radboud University Medical Center, Nijmegen, the Netherlands., Mahroo OA; Moorfields Eye Hospital NHS Foundation Trust, London, UK.; Institute of Ophthalmology, University College London, London, UK., Hargreaves I; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores, Liverpool, UK., Raymond FL; NIHR BioResource-Rare Diseases, Cambridge University Hospitals NHS Foundation Trust, Cambridge Biomedical Campus, Cambridge, UK.; Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK., Michaelides M; Moorfields Eye Hospital NHS Foundation Trust, London, UK.; Institute of Ophthalmology, University College London, London, UK., Rivolta C; Institute of Molecular and Clinical Ophthalmology Basel (IOB), Basel, Switzerland.; Department of Ophthalmology, University of Basel, Basel, Switzerland.; Department of Genetics and Genome Biology, University of Leicester, Leicester, UK., Kohl S; Institute for Ophthalmic Research, Centre for Ophthalmology, University of Tübingen, Tübingen, Germany., Roosing S; Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands.; Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands., Webster AR; Moorfields Eye Hospital NHS Foundation Trust, London, UK.; Institute of Ophthalmology, University College London, London, UK., Arno G; Moorfields Eye Hospital NHS Foundation Trust, London, UK. g.arno@ucl.ac.uk.; Institute of Ophthalmology, University College London, London, UK. g.arno@ucl.ac.uk.; North Thames Genomic Laboratory Hub, Great Ormond Street Hospital for Children, London, UK. g.arno@ucl.ac.uk.

Publikováno v: NPJ genomic medicine [NPJ Genom Med] 2022 Oct 20; Vol. 7 (1), pp. 60. Date of Electronic Publication: 2022 Oct 20.

COVID-19 and the Assessment of Coenzyme Q10.

Autor: Turton N; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, UK., Heaton RA; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, UK., Hargreaves IP; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, UK. I.P.Hargreaves@ljmu.ac.uk.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2022; Vol. 2511, pp. 355-365.