Scalability and process transfer of mesenchymal stromal cell production from monolayer to microcarrier culture using human platelet lysate.

Autor: Heathman TR; PCT, a Caladrius Company, NJ, USA; Centre for Biological Engineering, Loughborough University, Leicestershire, UK., Stolzing A; Centre for Biological Engineering, Loughborough University, Leicestershire, UK; Interdisciplinary Centre for Bioinformatics, University of Leipzig, Leipzig, Germany., Fabian C; Interdisciplinary Centre for Bioinformatics, University of Leipzig, Leipzig, Germany; Fraunhofer Institute for Cell Therapy and Immunology, Leipzig, Germany., Rafiq QA; Centre for Biological Engineering, Loughborough University, Leicestershire, UK; Aston Medical Research Institute, School of Life and Health Sciences, Aston University, Aston Triangle, Birmingham, UK., Coopman K; Centre for Biological Engineering, Loughborough University, Leicestershire, UK., Nienow AW; Centre for Biological Engineering, Loughborough University, Leicestershire, UK; Aston Medical Research Institute, School of Life and Health Sciences, Aston University, Aston Triangle, Birmingham, UK; Centre for Bioprocess Engineering, University of Birmingham, UK., Kara B; FUJIFILM Diosynth Biotechnologies, Billingham, UK., Hewitt CJ; Centre for Biological Engineering, Loughborough University, Leicestershire, UK; Aston Medical Research Institute, School of Life and Health Sciences, Aston University, Aston Triangle, Birmingham, UK. Electronic address: c.j.hewitt@aston.ac.uk.

Publikováno v: Cytotherapy [Cytotherapy] 2016 Apr; Vol. 18 (4), pp. 523-35.

Expansion, harvest and cryopreservation of human mesenchymal stem cells in a serum-free microcarrier process.

Autor: Heathman TR; Centre for Biological Engineering, Loughborough University, Leicestershire, LE11 3TU, UK., Glyn VA; Centre for Biological Engineering, Loughborough University, Leicestershire, LE11 3TU, UK., Picken A; Centre for Biological Engineering, Loughborough University, Leicestershire, LE11 3TU, UK., Rafiq QA; Centre for Biological Engineering, Loughborough University, Leicestershire, LE11 3TU, UK.; Aston Medical Research Institute, School of Life and Health Sciences, Aston University, Aston Triangle, Birmingham, B4 7ET., Coopman K; Centre for Biological Engineering, Loughborough University, Leicestershire, LE11 3TU, UK. k.coopman@lboro.ac.uk., Nienow AW; Centre for Biological Engineering, Loughborough University, Leicestershire, LE11 3TU, UK.; Centre for Bioprocess Engineering, University of Birmingham, B15 2TT, UK., Kara B; FUJIFILM Diosynth Biotechnologies, Billingham, TS23 1LH, UK., Hewitt CJ; Centre for Biological Engineering, Loughborough University, Leicestershire, LE11 3TU, UK.; Aston Medical Research Institute, School of Life and Health Sciences, Aston University, Aston Triangle, Birmingham, B4 7ET.

Publikováno v: Biotechnology and bioengineering [Biotechnol Bioeng] 2015 Aug; Vol. 112 (8), pp. 1696-707. Date of Electronic Publication: 2015 Apr 20.

Investigation of localized delivery of diclofenac sodium from poly(D,L-lactic acid-co-glycolic acid)/poly(ethylene glycol) scaffolds using an in vitro osteoblast inflammation model.

Autor: Sidney LE; 1 Division of Drug Delivery and Tissue Engineering, School of Pharmacy, Centre for Biomolecular Sciences, University of Nottingham , Nottingham, United Kingdom ., Heathman TR, Britchford ER, Abed A, Rahman CV, Buttery LD

Publikováno v: Tissue engineering. Part A [Tissue Eng Part A] 2015 Jan; Vol. 21 (1-2), pp. 362-73. Date of Electronic Publication: 2014 Oct 07.

Multiparameter flow cytometry for the characterisation of extracellular markers on human mesenchymal stem cells.

Autor: Chan AK; Centre for Biological Engineering, Department of Chemical Engineering, Loughborough University, Leicestershire, LE11 3TU, UK., Heathman TR, Coopman K, Hewitt CJ

Publikováno v: Biotechnology letters [Biotechnol Lett] 2014 Apr; Vol. 36 (4), pp. 731-41. Date of Electronic Publication: 2013 Dec 10.