Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Heather West Greenlee"'
Publikováno v:
Emerging Infectious Diseases, Vol 30, Iss 8, Pp 1651-1659 (2024)
White-tailed deer are susceptible to scrapie (WTD scrapie) after oronasal inoculation with the classical scrapie agent from sheep. Deer affected by WTD scrapie are difficult to differentiate from deer infected with chronic wasting disease (CWD). To a
Externí odkaz:
https://doaj.org/article/8810a057e2854d199606c73920ff5826
Publikováno v:
PLoS Pathogens, Vol 19, Iss 12, p e1011815 (2023)
Prion agents occur in strains that are encoded by the structure of the misfolded prion protein (PrPSc). Prion strains can influence disease phenotype and the potential for interspecies transmission. Little is known about the potential transmission of
Externí odkaz:
https://doaj.org/article/8ccd4ad15c464ba2add1606f4a5bec23
Autor:
Najiba Mammadova, Corey M. Summers, Robyn D. Kokemuller, Qing He, Shaowei Ding, Thierry Baron, Chenxu Yu, Rudy J. Valentine, Donald S. Sakaguchi, Anumantha G. Kanthasamy, Justin J. Greenlee, M. Heather West Greenlee
Publikováno v:
Neurobiology of Disease, Vol 121, Iss , Pp 1-16 (2019)
Parkinson's disease (PD) is a neurodegenerative disorder characterized by accumulation of misfolded α-synuclein within the central nervous system (CNS). Visual problems in PD patients are common, although retinal pathology associated with PD is not
Externí odkaz:
https://doaj.org/article/0866e59c39c44f0eb2dd5238873737de
Autor:
Najiba Mammadova, M. Heather West Greenlee, S. Jo Moore, Soyoun Hwang, Aaron D. Lehmkuhl, Eric M. Nicholson, Justin J. Greenlee
Publikováno v:
Frontiers in Veterinary Science, Vol 7 (2020)
Scrapie is a naturally occurring transmissible spongiform encephalopathy (TSE) that affects sheep and goats. Sheep and goats can be infected with scrapie as lambs or kids via contact with the placenta or placental fluids, or from ingestion of prions
Externí odkaz:
https://doaj.org/article/4e3743ee0a51473783bc1807ddabcfa5
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Currently, there is a lack of biomarkers to identify individuals in the early stages of Alzheimer’s disease (AD). A preponderance of evidence suggests that neurodegenerative processes that affect the brain, may also affect the retina. Using optical
Externí odkaz:
https://doaj.org/article/f977a5cc5f2a462f9a7d7a8dda2debd2
Autor:
S. Jo Moore, Catherine E. Vrentas, Soyoun Hwang, M. Heather West Greenlee, Eric M. Nicholson, Justin J. Greenlee
Publikováno v:
BMC Veterinary Research, Vol 14, Iss 1, Pp 1-11 (2018)
Abstract Background The Rocky Mountain elk (Cervus elaphus nelsoni) prion protein gene (PRNP) is polymorphic at codon 132, with leucine (L132) and methionine (M132) allelic variants present in the population. In elk experimentally inoculated with the
Externí odkaz:
https://doaj.org/article/6ac20657677a43a48f698872b2cdef61
Publikováno v:
Viruses, Vol 13, Iss 12, p 2453 (2021)
Prion diseases, also known as transmissible spongiform encephalopathies (TSEs), are a group of neurodegenerative protein misfolding diseases that invariably cause death. TSEs occur when the endogenous cellular prion protein (PrPC) misfolds to form th
Externí odkaz:
https://doaj.org/article/fcbadae3534f464bb048993497385768
Autor:
Eric D. Cassmann, Quazetta L. Brown, Alexis J. Frese, Zoe J. Lambert, M. Heather West Greenlee, Justin J. Greenlee
Publikováno v:
Veterinary Research Communications. 46:1377-1380
This study examines the effect of various infectious prion titers within the dynamic range as measured by ELISA on incubation period. We inoculated ovinized transgenic mice with seven decreasing dilutions of a fast-incubating scrapie strain. The high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b26c744d7a90f0e1b81b7108dec18789
https://doi.org/10.1007/s11259-022-10013-w
https://doi.org/10.1007/s11259-022-10013-w
Autor:
S. Jo Moore, Robert Kunkle, M. Heather West Greenlee, Eric Nicholson, Jürgen Richt, Amir Hamir, W. Ray Waters, Justin Greenlee
Publikováno v:
Emerging Infectious Diseases, Vol 22, Iss 12, Pp 2142-2145 (2016)
We challenged reindeer by the intracranial route with the agent of chronic wasting disease sourced from white-tailed deer, mule deer, or elk and tested for horizontal transmission to naive reindeer. Reindeer were susceptible to chronic wasting diseas
Externí odkaz:
https://doaj.org/article/489f4160e1be409e93e6158e138c6398
Autor:
Soyoun Hwang, M. Heather West Greenlee, Anne Balkema-Buschmann, Martin H. Groschup, Eric M. Nicholson, Justin J. Greenlee
Publikováno v:
Frontiers in Veterinary Science, Vol 4 (2018)
Bovine spongiform encephalopathy (BSE) belongs to a group of fatal prion diseases that result from the misfolding of the cellular prion protein (PrPC) into a pathogenic form (PrPSc) that accumulates in the brain. In vitro assays such as serial protei
Externí odkaz:
https://doaj.org/article/c9be778a52c44b579b5b4962559a462e