Zobrazeno 1 - 10 of 26 pro vyhledávání: '"Heather W, Pinkett"'
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Akademický článek
Microevolution in response to transient heme-iron restriction enhances intracellular bacterial community development and persistence.
Autor: Rachael L Hardison, Alistair Harrison, Rachel M Wallace, Derek R Heimlich, Meghan E O'Bryan, Robert P Sebra, Heather W Pinkett, Sheryl S Justice, Kevin M Mason
Publikováno v: PLoS Pathogens, Vol 14, Iss 10, p e1007355 (2018)
Bacterial pathogens must sense, respond and adapt to a myriad of dynamic microenvironmental stressors to survive. Adaptation is key for colonization and long-term ability to endure fluctuations in nutrient availability and inflammatory processes. We
Externí odkaz: https://doaj.org/article/071880675a8f486dbd0431d0e9a41899
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2
Detergent Alternatives: Membrane Protein Purification Using Synthetic Nanodisc Polymers
Autor: Valentina S. Dimitrova, Saemee Song, Alexandra Karagiaridi, Anika Marand, Heather W. Pinkett
Publikováno v: Methods in Molecular Biology ISBN: 9781071623671
Methods Mol Biol
The development of styrene maleic acid (SMA) and diisobutylene maleic acid (DIBMA) copolymers provides an alternative to traditional detergent extraction of integral membrane proteins. By inserting into the membrane, these polymers can extract membra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af89cd7dbe7e835488693d38a0a6b18f
https://doi.org/10.1007/978-1-0716-2368-8_20
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3
Oligopeptide-binding protein from nontypeable Haemophilus influenzae has ligand-specific sites to accommodate peptides and heme in the binding pocket
Autor: Kari J. Tanaka, Heather W. Pinkett
Publikováno v: Journal of Biological Chemistry. 294:1070-1082
In nontypeable Haemophilus influenzae (NTHi), the oligopeptide-binding protein (OppA) serves as the substrate-binding protein (SBP) of the oligopeptide transport system responsible for the import of peptides. We solved the crystal structure of nthiOp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f12d36384777df146952bb7ef76ead3b
https://doi.org/10.1074/jbc.ra118.004479
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5
Selective substrate uptake: The role of ATP-binding cassette (ABC) importers in pathogenesis
Autor: Heather W. Pinkett, Kevin M. Mason, Saemee Song, Kari J. Tanaka
Publikováno v: Biochimica et Biophysica Acta (BBA) - Biomembranes. 1860:868-877
The uptake of nutrients, including metals, amino acids and peptides are required for many biological processes. Pathogenic bacteria scavenge these essential nutrients from microenvironments to survive within the host. Pathogens must utilize a myriad
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c881015af26dda54a019cdbe484a24f7
https://doi.org/10.1016/j.bbamem.2017.08.011
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6
Microevolution in response to transient heme-iron restriction enhances intracellular bacterial community development and persistence
Autor: Kevin M. Mason, Sheryl S. Justice, Heather W. Pinkett, Rachel M. Wallace, Rachael L. Hardison, Robert Sebra, Meghan E. O’Bryan, Alistair Harrison, Derek R. Heimlich
Publikováno v: PLoS Pathogens
PLoS Pathogens, Vol 14, Iss 10, p e1007355 (2018)
Bacterial pathogens must sense, respond and adapt to a myriad of dynamic microenvironmental stressors to survive. Adaptation is key for colonization and long-term ability to endure fluctuations in nutrient availability and inflammatory processes. We
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f15b5efed7ab3505594490c576999d3e
http://europepmc.org/articles/PMC6205647
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7
Oligopeptide-binding protein from nontypeable
Autor: Kari J, Tanaka, Heather W, Pinkett
Publikováno v: The Journal of biological chemistry. 294(3)
In nontypeable Haemophilus influenzae (NTHi), the oligopeptide-binding protein (OppA) serves as the substrate-binding protein (SBP) of the oligopeptide transport system responsible for the import of peptides. We solved the crystal structure of nthiOp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e17674f4efd355ed106c3b96c5b73b54
https://pubmed.ncbi.nlm.nih.gov/30455346
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8
Diversity in ABC transporters: Type I, II and III importers
Autor: Heather W. Pinkett, Aekyung Park, Austin J. Rice
Publikováno v: Critical Reviews in Biochemistry and Molecular Biology
ATP-binding cassette transporters are multi-subunit membrane pumps that transport substrates across membranes. While significant in the transport process, transporter architecture exhibits a range of diversity that we are only beginning to recognize.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d9f07d9eecf83bbb3c2bcbb8fcec5ba
http://europepmc.org/articles/PMC4245157
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9
Small Substrate Transport and Mechanism of a Molybdate ATP Binding Cassette Transporter in a Lipid Environment
Autor: Amy L. Davidson, Alistair Harrison, Austin J. Rice, Frances Joan D. Alvarez, Heather W. Pinkett
Publikováno v: The Journal of Biological Chemistry
Background: Multiple ABC transporters work in concert to transport the same substrate. Results: MolBC-A allows for additional Mo uptake in periods of high external molybdate concentration. Conclusion: Utilizing the established transport mechanism, mo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a35920764164863182ecc41ef9f26c39
https://doi.org/10.1074/jbc.m114.563783
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