Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Heather Stanton"'
Autor:
Amanda J. Fosang, Zerina Lokmic, Stephanie J. Gauci, Eunice R. Lee, Suzanne B. Golub, Liliana Tatarczuch, Danny Chan, Eleanor J. Mackie, Nicole C. Walsh, Heather Stanton, Christopher B. Little, Natalie A. Sims
Publikováno v:
Matrix Biology. 83:77-96
Cartilage remodelling and chondrocyte differentiation are tightly linked to angiogenesis during bone development and endochondral ossification. To investigate whether collagenase-mediated cleavage of the major cartilage collagen (collagen II) plays a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::686aea46bf7d65ad764b2a1760af79a9
https://doi.org/10.1016/j.matbio.2019.08.001
https://doi.org/10.1016/j.matbio.2019.08.001
Autor:
Fraser Rogerson, Karena Last, Suzanne Golub, Stephanie Gauci, Heather Stanton, Katrina Bell, Amanda Fosang
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 3, p 573 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 3
International Journal of Molecular Sciences
Volume 20
Issue 3
A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS)-4 and ADAMTS-5 are the principal aggrecanases in mice and humans
however, mice lacking the catalytic domain of both enzymes (TS-4/5∆cat) have no skeletal phenotype, sugges
however, mice lacking the catalytic domain of both enzymes (TS-4/5∆cat) have no skeletal phenotype, sugges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0947e18f9b1020c9f527d6dde818229f
https://www.mdpi.com/1422-0067/20/3/573
https://www.mdpi.com/1422-0067/20/3/573
Autor:
Stephanie J. Gauci, Suzanne B. Golub, Heather Stanton, Paul Holden, Shireen R. Lamandé, Richard Wilson, Amanda J. Fosang, Hansen J. Kosasih, Fraser M. Rogerson, Vincenzo C. Russo
The metalloproteinase ADAMTS-5 (A disintegrin and metalloproteinase with thrombospondin motifs) degrades aggrecan, a proteoglycan essential for cartilage structure and function. ADAMTS-5 is the major aggrecanase in mouse cartilage, and is also likely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7065bee6a1583a1bf5996127e8e48e5
https://europepmc.org/articles/PMC4751368/
https://europepmc.org/articles/PMC4751368/
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1812:1616-1629
Proteoglycans are key components of extracellular matrices, providing structural support as well as influencing cellular behaviour in physiological and pathological processes. The diversity of proteoglycan function reported in the literature is equal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da84b256e4b7c0b1fd5eded218278f79
https://doi.org/10.1016/j.bbadis.2011.08.009
https://doi.org/10.1016/j.bbadis.2011.08.009
Autor:
Fraser M. Rogerson, Suzanne B. Golub, Heather Stanton, Christopher B. Little, Amanda J. Fosang
Publikováno v:
Nature Protocols. 6:388-404
Proteolysis of the cartilage proteoglycan aggrecan is a feature of arthritis. We present a method for analyzing aggrecanolysis in in vitro cultures of 3-week-old mouse femoral head cartilage based on traditional methods developed for large animal spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb6f1e2aa0062af5a3f6deee43686d6
https://doi.org/10.1038/nprot.2010.179
https://doi.org/10.1038/nprot.2010.179
Autor:
Amanda J. Fosang, Richard Harding, Heather Stanton, Richard A. Pierce, Megan J. Wallace, Stuart B. Hooper, Belinda Jane Joyce, Rochelle E Boland
Publikováno v:
The Journal of Physiology. 554:505-517
Although exogenous corticosteroids advance structural maturation of the fetal lung, they can adversely affect fetal lung and body growth. Our aim was to determine whether cortisol, at physiological doses, can enhance structural maturation of the hypo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f330c8b7f6c8f68b1c2eb62a94fab962
https://doi.org/10.1113/jphysiol.2003.055111
https://doi.org/10.1113/jphysiol.2003.055111
Autor:
Amanda J. Fosang, Heather Stanton
Publikováno v:
Matrix Biology. 21:425-428
We have recently observed marked increases in MMP-derived aggrecan fragments in extracts of cartilage stimulated with IL-1. The fragments were detected with an anti-DIPEN neoepitope antibody that is specific for fragments generated by MMP cleavage at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b81cf72ebed0c7f01e61b37801407be
https://doi.org/10.1016/s0945-053x(02)00035-5
https://doi.org/10.1016/s0945-053x(02)00035-5
Publikováno v:
Biochemical Journal. 364:181-190
Fragments of fibronectin occur naturally in vivo and are increased in the synovial fluid of arthritis patients. We have studied the 45kDa fragment (Fn-f 45), representing the N-terminal collagen-binding domain of fibronectin, for its ability to modul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b77beaf0553f3dd6f3bf47c73b68975a
https://doi.org/10.1042/bj3640181
https://doi.org/10.1042/bj3640181
Autor:
Gary Dew, Gillian Murphy, Heather Stanton, Rüdiger Vallon, Peter Angel, John J. Reynolds, Rosalind M. Hembry
Publikováno v:
Cell and Tissue Research. 299:385-394
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75c246735af5dec8af4a2df417afb7a7
https://doi.org/10.1007/s004410050036
https://doi.org/10.1007/s004410050036