Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Heather Sheppard-Tillman"'
Autor:
Yen-Nien Liu, Jiaoti Huang, Heather Sheppard-Tillman, Juan Juan Yin, Wei-Yu Chen, Yung-Sheng Chang
(A and B) TWIST1 (A) and miR-1 (B) expressions in patient samples at different clinical stages in the prostate cancer samples collected and analyzed at MSKCC. * vs. T2A. * p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30454a95df9e3b983249b78acd455c9b
https://doi.org/10.1158/0008-5472.22406153
https://doi.org/10.1158/0008-5472.22406153
Autor:
Yen-Nien Liu, Jiaoti Huang, Heather Sheppard-Tillman, Juan Juan Yin, Wei-Yu Chen, Yung-Sheng Chang
(A) Endogenous levels of miR-1 in a panel of prostate cancer cell lines. * vs. RasB1. (B) Relative EGFR expression levels in various prostate cancer cell lines. * vs. LNCap. (C) Cellular migration and invasion of LNCap and 22Rv1 cells following EGF t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59eeccd67e432355ac471e866fdb12ce
https://doi.org/10.1158/0008-5472.22406162
https://doi.org/10.1158/0008-5472.22406162
Autor:
Yen-Nien Liu, Jiaoti Huang, Heather Sheppard-Tillman, Juan Juan Yin, Wei-Yu Chen, Yung-Sheng Chang
(A and B) GSEA showed enrichment of two prostate cancer datasets, MSKCC (A) and TCGA (B), with EGFR signaling downregulation-responsive genes in cancers expressing high levels of miR-1. NES, normalized enrichment score; FDR, false discovery rate. (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c82a6e928101daecee11fbe00508f4dd
https://doi.org/10.1158/0008-5472.22406165.v1
https://doi.org/10.1158/0008-5472.22406165.v1
Autor:
Yen-Nien Liu, Jiaoti Huang, Heather Sheppard-Tillman, Juan Juan Yin, Wei-Yu Chen, Yung-Sheng Chang
(A) IF staining of RasB1 and PC3 cells with an antibody for EGFR following EGF and CI1033 treatment. Scale bars represent 50 µm. (B) IHC staining of FFPE cell blocks of RasB1 and PC3 cells with an antibody for p-EGFR (Y1068) following EGF and CI1033
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21af2b19710c9cb53e619409652b6db7
https://doi.org/10.1158/0008-5472.22406159
https://doi.org/10.1158/0008-5472.22406159
Autor:
Yen-Nien Liu, Jiaoti Huang, Heather Sheppard-Tillman, Juan Juan Yin, Wei-Yu Chen, Yung-Sheng Chang
(A) Mean TWIST1 levels in human normal (n=28), primary (n=98), and metastatic (n=13) prostate samples collected and analyzed at MSKCC. * vs. normal tissue; # vs. primary cancer tissues. * p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b7a63a4109dc6fb6fddfd9cff70e6f
https://doi.org/10.1158/0008-5472.22406156
https://doi.org/10.1158/0008-5472.22406156
Autor:
Yen-Nien Liu, Jiaoti Huang, Heather Sheppard-Tillman, Juan Juan Yin, Wei-Yu Chen, Yung-Sheng Chang
Table S1. Positions of AT-rich minimal consensus sequences (ATRSs). Table S2. Primer sequences of the 3'UTR and promoter reporter constructs. Table S3. Primer sequences for the qRT-PCR. Table S4. Antibody information for Western blotting. Table S5. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::514a334e3b6b9dbaf045be9a5d0e845b
https://doi.org/10.1158/0008-5472.22406150.v1
https://doi.org/10.1158/0008-5472.22406150.v1
Autor:
Jonathan Yen, Gregory A. Newby, Kalin Mayberry, Akshay Sharma, Michelle Richter, Thiyagaraj Mayuranathan, Kevin T. Zhao, Cicera R. Lazzarotto, Christophe Lechauve, Theodosia A. Kalfa, Elizabeth Thaman, Luke W. Koblan, Shondra M. Pruett-Miller, Heather Sheppard-Tillman, David R. Liu, Mitchell J. Weiss, Shengdar Q. Tsai, John F. Tisdale, Kaitly J. Woodard, Yoonjeong Jang, Christopher J. Podracky, Kelcee A. Everette, Shannon M. Miller, Tina Wang, Shaina N. Porter, Anton P. McCaffrey, Jordana M. Henderson, Yichao Li, Yu Yao
Publikováno v:
Nature
Sickle cell disease (SCD) is caused by a mutation in the β-globin gene HBB1. We used a custom adenine base editor (ABE8e-NRCH)2,3 to convert the SCD allele (HBBS) into Makassar β-globin (HBBG), a non-pathogenic variant4,5. Ex vivo delivery of mRNA
Autor:
Yen Nien Liu, Juan Juan Yin, Yung Sheng Chang, Jiaoti Huang, Wei Yu Chen, Heather Sheppard-Tillman
Publikováno v:
Cancer Research. 75:3077-3086
Dysregulation of the EGFR signaling axis enhances bone metastases in many solid cancers. However, the relevant downstream effector signals in this axis are unclear. miR-1 was recently shown to function as a tumor suppressor in prostate cancer cells,
Autor:
Victoria Seng, Juan Juan Yin, Heather Sheppard-Tillman, Wassim Abou-Kheir, Kathleen Kelly, Orla Casey, Yen-Nien Liu, Paul G. Hynes, Dong Hu, Lei Fang, Yong Wan, Philip Martin
Publikováno v:
Molecular and Cellular Biology. 32:941-953
Epithelial-mesenchymal transition (EMT) is implicated in various pathological processes within the prostate, including benign prostate hyperplasia (BPH) and prostate cancer progression. However, an ordered sequence of signaling events initiating carc
Autor:
Kathleen Kelly, Ming Yi, Yen-Nien Liu, Lei Fang, Heather Sheppard-Tillman, Victoria Seng, Philip Martin, Juan Juan Yin, Robert M. Stephens, Paul G. Hynes, Wassim Abou-Kheir, Orla Casey
Publikováno v:
Oncogene
Epithelial – mesenchymal transition (EMT) is a developmental program of signaling pathways that determine commitment to epithelial and mesenchymal phenotypes. In the prostate, EMT processes have been implicated in benign prostatic hyperplasia and p