Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Heather Schmitt"'
Autor:
Sandeep Gopalakrishnan, Shima Mehrvar, Sepideh Maleki, Heather Schmitt, Phyllis Summerfelt, Adam M. Dubis, Betsy Abroe, Thomas B. Connor, Joseph Carroll, Wendy Huddleston, Mahsa Ranji, Janis T. Eells
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract Photobiomodulation (PBM) by far-red (FR) to near-infrared (NIR) light has been demonstrated to restore the function of damaged mitochondria, increase the production of cytoprotective factors and prevent cell death. Our laboratory has shown t
Externí odkaz:
https://doaj.org/article/5aee5cb0967f41f39aadd3c6c79e264a
Autor:
W. Daniel Stamer, Michael A. Hauser, Guorong Li, William M. Johnson, Maria Gomez-Caraballo, Jenny Cui, Todd L. Fleming, Iris Navarro, Heather Schmitt, Chanyoung Lee, C. Ross Ethier, Sina Farsiu, Joseph M. Sherwood, Michael H. Elliott
Publikováno v:
FASEB J
Lysyl oxidase like-1 (LOXL1), a vital crosslinking enzyme in elastin fiber maintenance, is essential for the stability and strength of elastic vessels and tissues. Variants in the LOXL1 locus associate with a dramatic increase in risk of exfoliation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3aab10077a3ece4b0c661c8d33806d9
https://doi.org/10.1096/fj.202000702rr
https://doi.org/10.1096/fj.202000702rr
Autor:
Heather Schmitt, Astrid F. Nottebaum, Ute Ipe, Mitchell Brigell, Sarthak Mishra, Barbara Withers, Dietmar Vestweber, Brandi Soldo, Iris Navarro, Steve Pakola, W. Daniel Stamer, Kevin G. Peters, Guorong Li, Maria Gomez-Caraballo
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Tyrosine kinase with immunoglobulin-like and EGF-like domains 2 (Tie2) activation in Schlemm's canal (SC) endothelium is required for the maintenance of IOP, making the angiopoietin/Tie2 pathway a target for new and potentially disease modify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a084add86a0a7fd8c00ae9a18e8a3a68
https://pubmed.ncbi.nlm.nih.gov/33315051
https://pubmed.ncbi.nlm.nih.gov/33315051
Autor:
Yi Wei, Min Ni, Christina Adler, Yu Bai, Wen Fury, Carmelo Romano, Hua Yang, Ying Hu, Tao Yang, Maria Gomez-Caraballo, Heather Schmitt, Gaurang C. Patel, George D. Yancopoulos, W. Daniel Stamer
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Ocular hypertension is the primary and only modifiable risk factor for glaucoma, the leading cause of irreversible blindness. Intraocular pressure is regulated homeostatically by resistance to aqueous humor outflow through an architectur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3529fc6d49d1f399f55b06c39d14d4e
https://pubmed.ncbi.nlm.nih.gov/32439707
https://pubmed.ncbi.nlm.nih.gov/32439707
Autor:
Adam M. Dubis, Sepideh Maleki, Shima Mehrvar, Heather Schmitt, Phyllis Summerfelt, Joseph Carroll, Janis T. Eells, Sandeep Gopalakrishnan, Thomas B. Connor, Mahsa Ranji, Wendy E. Huddleston, Betsy Abroe
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Photobiomodulation (PBM) by far-red (FR) to near-infrared (NIR) light has been demonstrated to restore the function of damaged mitochondria, increase the production of cytoprotective factors and prevent cell death. Our laboratory has shown that FR PB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca9ed1b2806e0b7df6fb1c1fc4b8e32a
https://pubmed.ncbi.nlm.nih.gov/33230161
https://pubmed.ncbi.nlm.nih.gov/33230161
Publikováno v:
Exp Eye Res
High intraocular pressure (IOP) is the most common risk factor associated with glaucoma in humans. While lowering IOP is effective at reducing the rate of retinal ganglion cell (RGC) loss, to date, no treatment exists to directly preserve these cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9da0c72e277ce89126e3c09dac30517
https://pubmed.ncbi.nlm.nih.gov/32971093
https://pubmed.ncbi.nlm.nih.gov/32971093
Autor:
Nikolai P. Skiba, Michael A. Hauser, R. Rand Allingham, W. Daniel Stamer, Laura K. Finnegan, Inas F. Aboobakar, Maria Gomez-Caraballo, Heather Schmitt, William M. Johnson, David L. Corcoran, Megan Parker, Shelby Strickland
Publikováno v:
Hum Mol Genet
Individuals with pseudoexfoliation (PEX) syndrome exhibit various connective tissue pathologies associated with dysregulated extracellular matrix homeostasis. PEX glaucoma is a common, aggressive form of open-angle glaucoma resulting from the deposit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5289e6270c28a6b63754989bfdc1d316
https://europepmc.org/articles/PMC7390937/
https://europepmc.org/articles/PMC7390937/
Autor:
Rachel L. Fehrman, Cassandra L. Schlamp, Lian-Wang Guo, Robert W. Nickells, Huan Yang, Margaret E. Maes, Heather R. Pelzel, Heather Schmitt
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Inhibition or targeted deletion of histone deacetylase 3 (HDAC3) is neuroprotective in a variety neurodegenerative conditions, including retinal ganglion cells (RGCs) after acute optic nerve damage. Consistent with this, induced HDAC3 express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c32e8d742aaa8c3dcb053dcba77597f4
https://doi.org/10.1167/iovs.62.10.14
https://doi.org/10.1167/iovs.62.10.14
Publikováno v:
Preventing School Failure: Alternative Education for Children and Youth. 61:136-145
The growing English language learner (ELL) population in the United States warrants an examination of reading intervention effectiveness with this population. The reading achievement of ELLs is of particular concern due to the importance of reading s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5794cce3ce321c267cf7807e6e4a370a
https://doi.org/10.1080/1045988x.2016.1219301
https://doi.org/10.1080/1045988x.2016.1219301
Publikováno v:
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. 34(3)
Purpose: HDAC3 regulates nuclear atrophy as an early response to axonal injury in retinal ganglion cells (RGCs) following optic nerve crush (ONC). Since conditional knockout of Hdac3 prevents nuclear atrophy post ONC, HDAC3 selective inhibition with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e3573e0e2b1a1d7e4350dea88a32416
https://pubmed.ncbi.nlm.nih.gov/29211617
https://pubmed.ncbi.nlm.nih.gov/29211617