Výsledky vyhledávání - "Heather Romlein"

Cholera toxin B induced activation of murine macrophages exposed to a fixed bacterial immunogen

Autor: Heather Romlein, Constantine Bitsaktsis, Kari Wiedinger

Publikováno v: Therapeutic Advances in Vaccines. 3:155-163

Objectives: Previous studies have demonstrated that intranasal administration of inactivated (fixed) Francisella tularensis ( iFt) live vaccine strain (LVS) in conjunction with the mucosal adjuvant, cholera toxin B (CTB), provides full protection aga

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c60ee2432b33fafb135e16515e4c24b
https://doi.org/10.1177/2051013615613473

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Synthesis and immunological evaluation of a low molecular weight saccharide with TLR-4 agonist activity

Autor: Heather Romlein, Cecilia H. Marzabadi, Vikram Basava, Constantine Bitsaktsis

Publikováno v: Bioorganicmedicinal chemistry. 25(2)

The paucity of FDA approved adjuvants renders the synthesis, characterization, and use of new compounds as vaccine adjuvants, a necessity. For this purpose, a novel saccharide analog has been synthesized from glucosamine, pyruvylated galactose and 1,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af12d24a25e7a53debc3513dbe6380f9
https://pubmed.ncbi.nlm.nih.gov/27979367

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