Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Heather R. Sanders"'
Publikováno v:
Clinical chemistry. 65(8)
To the Editor: In 2011, Bystrom et al. developed a top-down liquid chromatography–high-resolution mass spectrometry (LC-HRMS)1 assay for insulin-like growth factor 1 (IGF-1) quantification (1). Using a similar method, Hines et al. subsequently repo
Autor:
Xi Zhang, Albert K Ho, Luis Rodriguez, Dan Jones, Ke Zhang, Heather R. Sanders, Hai-Rong Li, Qiulu Pan, Anthony Sferruzza, Frederic Waldman, Kevin Qu, Diedre Nguyen, Shih Min Cheng
Publikováno v:
The Journal of Molecular Diagnostics. 15:790-795
Detection of the BRAF V600E mutation is required for use of the BRAF inhibitor, vemurafenib, in patients with metastatic melanoma. Although the Roche Cobas 4800 BRAF V600 Mutation Test is approved, it detects primarily the single-nucleotide V600E mut
Autor:
David Ross, Cindy Barlan, John J. Sninsky, James Prentice, Heather R. Sanders, Feras M. Hantash, Kevin Qu, Xi Zhang, Beryl Crossley, Anthony Sferruzza, Hai-Rong Li, Joseph J. Catanese, Andrew Grupe, Lin Ma, David Wolfson, Frederic Waldman
Publikováno v:
Molecular diagnosistherapy. 20(3)
Several targeted therapies have been approved for treatment of solid tumors. Identification of gene mutations that indicate response to these therapies is rapidly progressing. A 34-gene next-generation sequencing (NGS) panel, developed and validated
Autor:
Amy M. Evans, Brian D. Foy, Linda S. Ross, Heather R. Sanders, Barry J. Beaty, Sarjeet S. Gill, Ken E. Olson
Publikováno v:
Insect Biochemistry and Molecular Biology. 35:1293-1307
The midgut of hematophagous insects is the initial site of infection by arthropod-borne viruses (arboviruses) and plays a crucial role in vector competence. To further understand processes that occur in the midgut in response to infection by an arbov
Autor:
Marc A. Sanidad, Frederic Waldman, Shih-Min Cheng, JoAnn C. Kelly, Heather R. Sanders, Feras M. Hantash, Fatih Z Boyar, Kevin Qu, Anthony Sferruzza, Patricia Chan, Vladimira Sulcova, Cindy Barlan
Publikováno v:
Cancer Research. 74:4675-4675
BACKGROUND: ALK, ROS1, and RET translocations are frequently detected in NSCLC patients. Crizotinib, a tyrosine kinase inhibitor (TKI), was approved by the FDA in 2011 to treat NSCLC in patients harboring ALK translocations as detected by an FDA-appr
Autor:
Heather R. Sanders, Debra Boles, Zhong J Zhang, Christine R. Bryke, Philip N. Mowrey, Steven Schonberg, Albert K Ho, Dan Jones, Jennifer A. Otani-Rosa, Aurelia Meloni-Ehrig, Zunyan Dai, Nicole C. Christacos, Marilyn L. Slovak, JoAnn C. Kelly, Qiulu Pan
Publikováno v:
Molecular Cytogenetics
Molecular Cytogenetics, Vol 5, Iss 1, p 44 (2012)
Molecular Cytogenetics, Vol 5, Iss 1, p 44 (2012)
Background Anaplastic lymphoma receptor tyrosine kinase (ALK) gene rearrangements have been reported in 2-13% of patients with non-small cell lung cancer (NSCLC). Patients with ALK rearrangements do not respond to EGFR-specific tyrosine kinase inhibi
Autor:
Heather R. Sanders, Jay Scheerle, Jean-Marie Bruey, JoAnn C. Kelly, Maher Albitar, Hai-Rong Li, Constance Novick, Aurelia Meloni-Ehrig
Publikováno v:
Cancer genetics. 204(1)
Chromosomal inversions within chromosome 2p, resulting in fusions between the echinoderm microtubule-associated protein-like 4 ( EML4 ) and anaplastic lymphoma kinase ( ALK ) genes, are a recent focus of treatment options for non–small cell lung ca
Autor:
Heather R. Sanders, Maher Albitar
Publikováno v:
Cancer genetics and cytogenetics. 203(1)
Lung cancer is the leading cause of cancer-related deaths, with non-small-cell lung cancer (NSCLC) accounting for approximately 85% of cases. A significant proportion of NSCLC cases are not diagnosed until a late stage, when aggressive treatments are
Autor:
Heather R. Sanders, Wanlong Ma, Hagop M. Kantarjian, Amber C. Donahue, Chen-Hsiung Yeh, Jean Marie Bruey, Zeev Estrov, Maher Albitar, Susan O'Brien, Michael J. Keating
Publikováno v:
Leukemia research. 34(10)
Ki-67 is a nuclear antigen that is expressed in all stages of the cell cycle, except G(0), and is widely used as a marker of cellular proliferation in human tumors. We recently showed that elevated levels of Ki-67 circulating in plasma (cKi-67) are a
Autor:
Heather R. Sanders, Anthony Sferruzza, Xi Zhang, Feras M. Hantash, Jay Wohlgemuth, Andrew Grupe, David Ross, Frederic Waldman, Beryl Crossley, Hai-Rong Li, James Prentice, Joseph J. Catanese, Lin Ma, Kevin Qu, Cindy Barlan, John J. Sninsky
Publikováno v:
Journal of Clinical Oncology. 33:e22132-e22132
e22132 Background: Several targeted therapies have been approved for treatment of solid tumors. Identification of gene mutations associated with response to these targeted therapies is rapidly prog...