Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Heather R Pelzel"'
Publikováno v:
Trends in Teaching Experimentation in the Life Sciences ISBN: 9783030985912
Collaboration is essential to modern biological research, and the ability for scientists to be an effective member of a diverse team is critical for professional and personal growth. Modeling collaborative research in an undergraduate course provides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73e0c95c47827f5551860d646f381b3b
https://doi.org/10.1007/978-3-030-98592-9_22
https://doi.org/10.1007/978-3-030-98592-9_22
Autor:
Rachel L. Fehrman, Cassandra L. Schlamp, Lian-Wang Guo, Robert W. Nickells, Huan Yang, Margaret E. Maes, Heather R. Pelzel, Heather Schmitt
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Inhibition or targeted deletion of histone deacetylase 3 (HDAC3) is neuroprotective in a variety neurodegenerative conditions, including retinal ganglion cells (RGCs) after acute optic nerve damage. Consistent with this, induced HDAC3 express
Autor:
Heather R. Pelzel, Robert W. Nickells
Evaluating gene expression changes presents one of the most powerful interrogative approaches to study the molecular, biochemical, and cellular pathways associated with glaucomatous disease pathology. Technologies to study gene expression profiles in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b46a945c362a62c659d69230fe8de5d7
https://europepmc.org/articles/PMC4628862/
https://europepmc.org/articles/PMC4628862/
Publikováno v:
Molecular Neurodegeneration
Background Optic nerve damage initiates a series of early atrophic events in retinal ganglion cells (RGCs) that precede the BAX-dependent committed step of the intrinsic apoptotic program. Nuclear atrophy, including global histone deacetylation, hete
Autor:
Heather R. Pelzel, Robert W. Nickells
The study of epigenetic changes is experiencing a period of explosive growth, in part, due to the fact that epigenetic regulation has been linked to everything from cancer to obesity and from tissue differentiation to degeneration. An epigenetic chan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53862510cd950f1a19e060a5b6c091e4
https://europepmc.org/articles/PMC3382294/
https://europepmc.org/articles/PMC3382294/
Autor:
Anthony P Adamis, Grazyna Adamus, Daniel M Albert, Ann-Christin Albertsmeyer, Nishani Amerasinghe, Michael G Anderson, Sally S Atherton, Tin Aung, Rebecca S Bahn, David Sander Bardenstein, Neal P Barney, David C Beebe, Adrienne Berman, Audrey M Bernstein, Pooja Bhat, Douglas Borchman, Stephen Brocchini, Claude Burgoyne, Michelle Trager Cabrera, Richard J Cenedella, Jin-Hong Chang, Aimee Chappelow, Anuj Chauhan, Abbot F Clark, Ellen B Cook, Zélia M Corrêa, Scott Cousins, Gerald Cox, Scott Adam Croes, Karl G Csaky, Annegret Hella Dahlmann-Noor, Reza Dana, Helen Danesh-Meyer, Julie T Daniels, Darlene A Dartt, Mohammad H Dastjerdi, Nigel W Daw, Daniel G Dawson, Alejandra de Alba Campomanes, Joseph L Demer, Suzanne M Dintzis, J Crawford Downs, Henry Edelhauser, David Ellenberg, Victor Elner, Steven K Fisher, Robert Folberg, C Stephen Foster, Gary N Foulks, Frederick T Fraunfelder, Frederick W Fraunfelder, Anne Fulton, Ronald Gaster, Stylianos Georgoulas, Michael S Gilmore, Ilene K Gipson, Michaël J A Girard, Lynn K Gordon, Irene Gottlob, John D Gottsch, Frank M Graziano, Hans E Grossniklaus, Deborah Grzybowski, Clyde Guidry, Neeru Gupta, David H Gutmann, Vinay Gutti, John R Guy, J William Harbour, Mary Elizabeth Hartnett, Sohan S Hayreh, Susan Heimer, Robert Hess, Nancy M Holekamp, Suber S Huang, Sudha K Iyengar, Allen T Jackson, L Alan Johnson, Peter F Kador, Alon Kahana, Randy Kardon, Maria Cristina Kenney, Timothy Scott Kern, Peng Tee Khaw, Alice S Kim, Henry Klassen, Paul Knepper, Jane F Koretz, Mirunalini Kumaradas, Jonathan H Lass, David Lederer, Mark Lesk, Leonard A Levin, Geoffrey P Lewis, Zhuqing Li, Amy Lin, Robert A Linsenmeier, Robert Listernick, Martin Lubow, Andrew Maniotis, Pascale Massin, Katie Matatall, Russell L McCally, Stephen D McLeod, Muhammad Memon, Joan W Miller, Austin K Mircheff, Jay Neitz, Maureen Neitz, Christine C Nelson, Robert Nickells, Robert B Nussenblatt, Joan M O’Brien, Daniel T Organisciak, Michel Paques, Heather R Pelzel, Shamira Perera, Eric A Pierce, Jean Pournaras, Jonathan T Pribila, Frank A Proudlock, Xiaoping Qi, Narsing A Rao, Robert Ritch, Joseph F Rizzo, Michael D Roberts, James T Rosenbaum, Barry Rouse, Daniel R Saban, Alfredo A Sadun, Abbas K Samadi, Pranita Sarangi, Andrew P Schachat, Joel E Schechter, A Reagan Schiefer, Ursula Schlötzer-Schrehardt, Ingo Schmack, Leopold Schmetterer, Genevieve Aleta Secker, Srilakshmi M Sharma, James A Sharpe, Heather Sheardown, Alex Shortt, Ying-Bo Shui, Ian Sigal, James L Stahl, Roger F Steinert, Arun N E Sundaram, Janet S Sunness, Nathan T Tagg, Daniela Toffoli, Cynthia A Toth, Elias I Traboulsi, James C Tsai, Budd Tucker, Russell N Van Gelder, Hans Eberhard Völcker, Christopher S von Bartheld, Jianhua Wang, Judith West-Mays, Corey B Westerfeld, Steven E Wilson, Fabricio Witzel de Medeiros, Chih-Wei Wu, Ai Yamada, Steven Yeh, Thomas Yorio, Michael J Young, Terri L Young, Yeni H Yücel, Beatrice Y J T Yue, Marco A Zarbin, Xinyu Zhang, Mei Zheng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71fbe8bdeb3488c1ff142b24c37da781
https://doi.org/10.1016/b978-0-7020-2983-7.00086-3
https://doi.org/10.1016/b978-0-7020-2983-7.00086-3
Autor:
Heather R, Pelzel, Cassandra L, Schlamp, Gretchen L, Poulsen, James A, Ver Hoeve, T Michael, Nork, Robert W, Nickells
Publikováno v:
Molecular vision. 12
This study was designed to test the hypothesis that photoreceptors are adversely affected in glaucoma. As a measure of this effect, we examined the levels of rod opsin, and red/green and blue cone opsin mRNAs in monkeys with experimental ocular hyper
Autor:
Cassandra L. Schlamp, Robert W. Nickells, Heather R. Pelzel, Michael Waclawski, Malissa Kay Shaw
Publikováno v:
Investigative Opthalmology & Visual Science. 53:1428
Axonal degeneration and retinal ganglion cell body atrophy and death are the fundamental characteristics of glaucomatous optic neuropathies.1 The identification of intrinsic apoptosis in glaucomatous ganglion cell somas2 has led to the hypothesis tha
Publikováno v:
BMC Neuroscience
BMC Neuroscience, Vol 11, Iss 1, p 62 (2010)
BMC Neuroscience, Vol 11, Iss 1, p 62 (2010)
Background Silencing of normal gene expression occurs early in the apoptosis of neurons, well before the cell is committed to the death pathway, and has been extensively characterized in injured retinal ganglion cells. The causative mechanism of this