Zobrazeno 1 - 2
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pro vyhledávání: '"Heather Oppenheim"'
Autor:
Peter Tontonoz, Christopher D.M. Fletcher, Bruce M. Spiegelman, Ronald M. Evans, Barry M. Forman, Samuel Singer, Heather Oppenheim, Soner Altiok, Elisabetta Mueller, Regina P. Brun, Jonathan A. Fletcher, Pasha Sarraf
Publikováno v:
Proceedings of the National Academy of Sciences. 94:237-241
Induction of terminal differentiation represents a promising therapeutic approach to certain human malignancies. The peroxisome proliferator-activated receptor gamma (PPAR gamma) and the retinoid X receptor alpha (RXR alpha) form a heterodimeric comp
Autor:
Jennifer Smoluk, Enrique Saez, Stuart H. Yuspa, Bruce M. Spiegelman, Heather Oppenheim, Susan E. Rutberg, Elisabetta Mueller
Publikováno v:
Cell. 82(5)
The proto-oncogene c-fos is a major nuclear target for signal transduction pathways involved in the regulation of cell growth, differentiation, and transformation. Using the multistep skin carcinogenesis model, we have directly tested the ability of