Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Heather N. Tinsley"'
Autor:
Heather N. Tinsley
Publikováno v:
Journal of Microbiology & Biology Education, Vol 17, Iss 3, Pp 380-388 (2016)
Despite the importance of scientific literacy, many foundational science courses are plagued by low student engagement and performance. In an attempt to improve student outcomes, an introductory biology course for nonscience majors was redesigned to
Externí odkaz:
https://doaj.org/article/da9c6176e74b409f9953848824564d86
Autor:
Gary A. Piazza, Adam B. Keeton, Heather N. Tinsley, Jason D. Whitt, Bernard D. Gary, Bini Mathew, Raj Singh, William E. Grizzle, Robert C. Reynolds
Publikováno v:
Pharmaceuticals, Vol 3, Iss 5, Pp 1652-1667 (2010)
There is compelling evidence that nonsteroidal anti-inflammatory drugs (NSAIDs) and cyclooxygenase-2 selective inhibitors have antineoplastic activity, but toxicity from cyclooxygenase (COX) inhibition and the suppression of physiologically important
Externí odkaz:
https://doaj.org/article/8f94bf6b294249a785d4a164e17fae0f
Autor:
Heather N. Tinsley, Bini Mathew, Xi Chen, Yulia Y. Maxuitenko, Nan Li, Whitney M. Lowe, Jason D. Whitt, Wei Zhang, Bernard D. Gary, Adam B. Keeton, William E. Grizzle, Clinton J. Grubbs, Robert C. Reynolds, Gary A. Piazza
Publikováno v:
Cancers
Volume 15
Issue 3
Pages: 646
Volume 15
Issue 3
Pages: 646
The nonsteroidal anti-inflammatory drug (NSAID) sulindac demonstrates attractive anticancer activity, but the toxicity resulting from cyclooxygenase (COX) inhibition and the suppression of physiologically important prostaglandins precludes its long-t
Autor:
Heather N. Tinsley
Publikováno v:
CourseSource. 6
Publikováno v:
The breast journal. 25(4)
Autor:
Perrin F. Windham, Heather N. Tinsley
Publikováno v:
Seminars in Cancer Biology. 31:106-110
One in eight women in the United States will be diagnosed with invasive breast cancer in her lifetime. Advances in therapeutic strategies, diagnosis, and improved awareness have resulted in a significant reduction in breast cancer related mortality.
Publikováno v:
Cancers, Vol 6, Iss 1, Pp 436-458 (2014)
Cancers
Cancers
For more than four decades, the cyclic nucleotides cyclic AMP (cAMP) and cyclic GMP (cGMP) have been recognized as important signaling molecules within cells. Under normal physiological conditions, cyclic nucleotides regulate a myriad of biological p
Autor:
Gary A. Piazza, Marwa Saeed Hany, Bernard D. Gary, Heather N. Tinsley, Ashraf H. Abadi, Amal Abdel Haleem Eissa, Shimaa Awadain Elsharif
Publikováno v:
Chemical and Pharmaceutical Bulletin. 61:405-410
Analogues with the scaffolds of 3-cyano-4-alkoxyphenyl-6-bromoaryl-2-pyridone and 2-amino-3-cyano-4-alkoxyphenyl-6-bromoarylpyridine were synthesized. Cyclization of the 2-amino derivatives with formic acid and formamide gave the corresponding pyrido
Autor:
Bernard D. Gary, Ashraf H. Abadi, Alexandra M. Fajardo, Amal H. Ali, Gary A. Piazza, Shreen M. El-Nashar, Nermin S. Ahmed, Matthias Negri, Heather N. Tinsley
Publikováno v:
European Journal of Medicinal Chemistry. 57:329-343
By studying the co-crystal information of interactions between PDE5 and its inhibitors, forty new tetrahydro-β-carbolines based-analogues were synthesized, and tested for their PDE5 inhibition. Some compounds were as active as tadalafil in inhibitin