Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Heather N. Carter"'
Publikováno v:
The Journal of Physiology. 596:3567-3584
Key points A healthy mitochondrial pool is dependent on the removal of dysfunctional organelles via mitophagy, but little is known about how mitophagy is altered with ageing and chronic exercise. Chronic contractile activity (CCA) is a standardized e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39fcc33d1184098953f8e55289f03c62
https://doi.org/10.1113/jp275998
https://doi.org/10.1113/jp275998
Publikováno v:
Journal of Applied Physiology. 124:1605-1615
Mitochondrial impairments are often noted in aged skeletal muscle. The transcriptional coactivator peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is integral to maintaining mitochondria, and its expression declines in aged mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::853dcca24ac5ef2c5e724a20853400f6
https://doi.org/10.1152/japplphysiol.01110.2017
https://doi.org/10.1152/japplphysiol.01110.2017
Publikováno v:
Sarcopenia ISBN: 9780429155260
Sarcopenia
Sarcopenia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a4644be58c5c1898e9e388dbdb2d4c2
https://doi.org/10.1201/9780429155260-12
https://doi.org/10.1201/9780429155260-12
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7e30eb17fbc8d02e9062013f1a0464b
https://doi.org/10.1096/fasebj.2020.34.s1.04597
https://doi.org/10.1096/fasebj.2020.34.s1.04597
Autor:
David A. Hood, Alexa Parousis, Claudia Tran, Zahra S. Mesbah Moosavi, Marion Pauly, Avigail T. Erlich, Heather N. Carter
Publikováno v:
Autophagy. 14(11)
Macroautophagy/autophagy is a survival mechanism that facilitates protein turnover in post-mitotic cells in a lysosomal-dependent process. Mitophagy is a selective form of autophagy, which arbitrates the selective recognition and targeting of aberran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b413e92a075d6d77765c30b4b614af7
https://pubmed.ncbi.nlm.nih.gov/30078345
https://pubmed.ncbi.nlm.nih.gov/30078345
Publikováno v:
The Biochemical journal. 473(15)
Skeletal muscle is a tissue with a low mitochondrial content under basal conditions, but it is responsive to acute increases in contractile activity patterns (i.e. exercise) which initiate the signalling of a compensatory response, leading to the bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b979cb70b0080c24fad55289b35f26cd
https://pubmed.ncbi.nlm.nih.gov/27470593
https://pubmed.ncbi.nlm.nih.gov/27470593
Publikováno v:
American Journal of Physiology-Cell Physiology. 303:C447-C454
Skeletal muscle undergoes remarkable adaptations in response to chronic decreases in contractile activity, such as a loss of muscle mass, decreases in both mitochondrial content and function, as well as the activation of apoptosis. Although these ada
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa89347a9efe9922afbaf4e51809d9e1
https://doi.org/10.1152/ajpcell.00451.2011
https://doi.org/10.1152/ajpcell.00451.2011
Publikováno v:
The FASEB Journal. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ec976a0e045be277098d08ab21d436b
https://doi.org/10.1096/fasebj.29.1_supplement.826.2
https://doi.org/10.1096/fasebj.29.1_supplement.826.2
Autor:
Heather N. Carter, Matthew J. Crilly, Marion Pauly, David A. Hood, Anna Vainshtein, Jonathan M. Memme, Chris C. W. Chen, Liam D. Tryon
Exercise is a well-known stimulus for the expansion of the mitochondrial pool within skeletal muscle. Mitochondria have a remarkable ability to remodel their networks and can respond to an array of signaling stimuli following contractile activity to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05d2cef71ee7c6754c99be5f1a9872e9
https://doi.org/10.1016/bs.pmbts.2015.07.007
https://doi.org/10.1016/bs.pmbts.2015.07.007
Publikováno v:
American journal of physiology. Cell physiology. 306(3)
An acute bout of exercise activates downstream signaling cascades that ultimately result in mitochondrial biogenesis. In addition to inducing mitochondrial synthesis, exercise triggers the removal of damaged cellular material via autophagy and of dys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206edc08c1df164411c69e9804a35758
https://pubmed.ncbi.nlm.nih.gov/24284795
https://pubmed.ncbi.nlm.nih.gov/24284795