Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Heather N Larson"'
Autor:
Taylor J Abele, Zachary P Billman, Lupeng Li, Carissa K Harvest, Alexia K Bryan, Gabrielle R Magalski, Joseph P Lopez, Heather N Larson, Xiao-Ming Yin, Edward A Miao
Publikováno v:
eLife, Vol 12 (2023)
Pyroptosis and apoptosis are two forms of regulated cell death that can defend against intracellular infection. When a cell fails to complete pyroptosis, backup pathways will initiate apoptosis. Here, we investigated the utility of apoptosis compared
Externí odkaz:
https://doaj.org/article/7eb48fcbd0d1487191217dd2ceb4740a
Autor:
Lupeng Li, Stephen B. Kovacs, Ine Jørgensen, Heather N. Larson, Helen M. Lazear, Edward A. Miao
Publikováno v:
Viruses, Vol 14, Iss 9, p 2034 (2022)
Herpes simplex virus type 1 (HSV-1) infection can manifest locally as mucocutaneous lesions or keratitis and can also spread to the central nervous system to cause encephalitis. HSV-1 establishes a lifelong latent infection and neither cure nor vacci
Externí odkaz:
https://doaj.org/article/87991eda8af943a9861a5e2859365cda
Autor:
Taylor J. Abele, Zachary P. Billman, Lupeng Li, Carissa K. Harvest, Alexia K. Bryan, Gabrielle R Magalski, Joseph P Lopez, Heather N. Larson, Xiao-Ming Yin, Edward A. Miao
Publikováno v:
bioRxiv
Pyroptosis and apoptosis are two forms of regulated cell death that can defend against intracellular infection. Although pyroptosis and apoptosis have distinct signaling pathways, when a cell fails to complete pyroptosis, backup pathways will initiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9003c8cf9d4ba0dbe8397c9707cc9f72
https://europepmc.org/articles/PMC10187329/
https://europepmc.org/articles/PMC10187329/
Autor:
Carissa K. Harvest, Taylor J. Abele, Chen Yu, Cole J. Beatty, Megan E. Amason, Zachary P. Billman, Morgan A. DePrizio, Carolyn A. Lacey, Vivien I. Maltez, Heather N. Larson, Benjamin D. McGlaughon, Daniel R. Saban, Stephanie A. Montgomery, Edward A. Miao
Publikováno v:
bioRxiv
SUMMARYGranulomas often form around pathogens that cause chronic infections. Here, we discover a novel granuloma model in mice.Chromobacterium violaceumis an environmental bacterium that stimulates granuloma formation that not only successfully walls
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71b045bf06719588c8b1ed3aa7e83024
https://europepmc.org/articles/PMC10028874/
https://europepmc.org/articles/PMC10028874/
Autor:
Kengo Nozaki, Vivien I. Maltez, Manira Rayamajhi, Alan L. Tubbs, Joseph E. Mitchell, Carolyn A. Lacey, Carissa K. Harvest, Lupeng Li, William T. Nash, Heather N. Larson, Benjamin D. McGlaughon, Nathaniel J. Moorman, Michael G. Brown, Jason K. Whitmire, Edward A. Miao
Publikováno v:
Nature
Among the caspases that cause regulated cell death, a unique function for caspase-7 remained elusive. Caspase-3 executes apoptosis, whereas caspase-7 is typically considered an inefficient back-up. Caspase-1 activates gasdermin D pores to lyse the ce
Publikováno v:
Journal of Biological Chemistry. 280:30550-30556
Mitochondrial aldehyde dehydrogenase (ALDH2) is the major enzyme that oxidizes ethanol-derived acetaldehyde. A nearly inactive form of the enzyme, ALDH2*2, is found in about 40% of the East Asian population. This variant enzyme is defined by a glutam
Autor:
Heather N, Larson, Jianzhong, Zhou, Zhiqiang, Chen, Jonathan S, Stamler, Henry, Weiner, Thomas D, Hurley
Publikováno v:
The Journal of biological chemistry. 282(17)
The common mitochondrial aldehyde dehydrogenase (ALDH2) ALDH2(*)2 polymorphism is associated with impaired ethanol metabolism and decreased efficacy of nitroglycerin treatment. These physiological effects are due to the substitution of Lys for Glu-48