Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Heather Metz"'
Autor:
Li-Qun Fan, Yvette Latchman, Jenny Chang, Valerie Odegard, Heather Metz, Ty Brender, Brenda Stevens, Damion Winship, Jamie Brevik, Michael Comeau, Monica Childs, Hengyu Xu, Jonathan Grey, Jeffrey Adamo, Ben Setter, Ray Carrillo, Sean Smith, Phil Tan, Robert DuBose, Peter Baum
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/9e3f9c3e665b493888a885f84d083f35
Autor:
Damion Winship, Ray Carrillo, Brenda L. Stevens, Jonathan Grey, Hengyu Xu, Ben Setter, Robert F. Dubose, Peter R. Baum, Jenny C. Chang, Heather Metz, Li-Qun Fan, Ty Brender, Jeffrey Adamo, Sean W. Smith, Jamie Brevik, Yvette Latchman, Michael R. Comeau, Monica Childs, Phil Tan, Valerie Odegard
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background SBT6290 is a novel therapeutic comprised of a selective TLR8 agonist conjugated to a Nectin-4-specific monoclonal antibody, designed for systemic delivery and tumor-localized activation of myeloid cells. Nectin-4 is a cell surface adhesion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::194826442d9255b60ef94c5300b86ac5
https://doi.org/10.1136/jitc-2020-sitc2020.0712
https://doi.org/10.1136/jitc-2020-sitc2020.0712
Autor:
Sean W. Smith, Hengyu Xu, Peter R. Baum, Yvette Latchman, Jamie Brevik, Ty Brender, Phil Tan, Jeffrey Adamo, Valerie Odegard, Michael R. Comeau, Li-Qun Fan, Monica Childs, Jenny C. Chang, Ben Setter, Robert F. Dubose, Damion Winship, Heather Metz, Brenda L. Stevens
Publikováno v:
Cancer Research. 80:4537-4537
SBT6050, a novel therapeutic comprised of a potent toll-like receptor (TLR) 8 agonist conjugated to a HER2-directed monoclonal antibody that binds an epitope distinct from trastuzumab, is designed for systemic delivery and tumor-localized activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb16e44c349c30e8b5c3dabbc5022481
https://doi.org/10.1158/1538-7445.am2020-4537
https://doi.org/10.1158/1538-7445.am2020-4537
Autor:
Sean W. Smith, Jeffrey Adamo, Damion Winship, Yvette Latchman, Valerie Odegard, Kara Moyes, Heather Metz, Jenny C. Chang, Ty Brender, Phil Tan, Michael R. Comeau, Jamie Brevik, Robert F. Dubose, Monica Childs, Li-Qun Fan, Hengyu Xu, Peter R. Baum, Ben Setter
Publikováno v:
Journal of Clinical Oncology. 38:3110-3110
3110 Background: Solid tumors are replete with myeloid cells which, when activated, drive potent anti-tumor responses. Clinical development of systemically administered myeloid cell agonists, however, has been hindered by acute toxicities due to peri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cc6cc932702b5a630ec49eddc71e07b
https://doi.org/10.1200/jco.2020.38.15_suppl.3110
https://doi.org/10.1200/jco.2020.38.15_suppl.3110
Autor:
Heather Metz, Alison VanSchoiack, Quoc Huynh, Sarah H. Warren, Kristi Barker, Lucas Dennis, Jingjing Gong, Beechem Joseph M, Chris Merritt, Yan Liang
Publikováno v:
Cancer Research. 78:3858-3858
Mouse models of cancer are an invaluable biomedical research tool in which characterization of the abundance, distribution and co-localization of immuno-oncology targets is critical for the advancement of disease understanding. Nanostring Technologie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e867010859a3e9ea64e1fbb43d16a4c5
https://doi.org/10.1158/1538-7445.am2018-3858
https://doi.org/10.1158/1538-7445.am2018-3858
Autor:
Heather Metz, Jamie Kuhar, Warren Carter, Alyssa Rosenbloom, Gary K. Geiss, Yan Liang, Lisa Y. Bogatzki, Joseph M. Beechem, Kelly Miller, Arya Bahrami
Publikováno v:
Alzheimer's & Dementia. 15:P612-P612
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6de251fa596724b305648be8e53a97f8
https://doi.org/10.1016/j.jalz.2019.06.2511
https://doi.org/10.1016/j.jalz.2019.06.2511
Publikováno v:
The Journal of Immunology. 200:174.23-174.23
Nanostring Technologies’ Digital Spatial Profiling (DSP) technology allows for the simultaneous analysis of 10’s to 100’s of proteins from discrete regions of interest (ROI), providing a morphological context to multiplexed protein analysis. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bca97df0eeb58c4606d505cf6493c40e
https://doi.org/10.4049/jimmunol.200.supp.174.23
https://doi.org/10.4049/jimmunol.200.supp.174.23
Autor:
Ty Brender, Jamie Brevik, Li-Qun Fan, Phil Tan, Valerie Odegard, Jeffrey Adamo, Damion Winship, Sean W. Smith, Yvette Latchman, Kara Moyes, Heather E. Metz, Monica Childs, Jenny R Chang, Ben Setter, Hengyu Xu, Peter R. Baum, Robert F. Dubose
Publikováno v:
Cancer Research. 80:PD4-09
Despite advances in treatment options for patients with HER2-expressing tumors, significant unmet medical need remains. Of note, checkpoint inhibition (CPI) therapy has been largely ineffective in HER2-expressing tumors, likely due to the absence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70f988ea76110072b5cae2bb2ca08e67
https://doi.org/10.1158/1538-7445.sabcs19-pd4-09
https://doi.org/10.1158/1538-7445.sabcs19-pd4-09