Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Heather McGowan"'
Autor:
Siwei Zhang, Winton Moy, Hanwen Zhang, Catherine Leites, Heather McGowan, Jianxin Shi, Alan R. Sanders, Zhiping P. Pang, Pablo V. Gejman, Jubao Duan
Publikováno v:
Stem Cell Research, Vol 29, Iss , Pp 88-98 (2018)
Chromatin accessibility to transcription factors (TFs) strongly influences gene transcription and cell differentiation. However, a mechanistic understanding of the transcriptional control during the neuronal differentiation of human induced pluripote
Externí odkaz:
https://doaj.org/article/282ab3a710e04d33b4c870faabbe48ed
Autor:
Heather McGowan, Vincent R. Mirabella, Aula Hamod, Aziz Karakhanyan, Nicole Mlynaryk, Jennifer C. Moore, Jay A. Tischfield, Ronald P. Hart, Zhiping P. Pang
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 10 (2018)
Non-coding RNA, including microRNA (miRNA) serves critical regulatory functions in the developing brain. The let-7 family of miRNAs has been shown to regulate neuronal differentiation, neural subtype specification, and synapse formation in animal mod
Externí odkaz:
https://doaj.org/article/76ab7ffd7940456480c2b11fdad298d2
Autor:
Heather McGowan, Zhiping P. Pang
Publikováno v:
Cell Regeneration, Vol 4, Iss 1 (2015)
Methyl-CpG-binding protein 2 (MeCP2), encoded by the gene MECP2, is a transcriptional regulator and chromatin-remodeling protein, which is ubiquitously expressed and plays an essential role in the development and maintenance of the central nervous sy
Externí odkaz:
https://doaj.org/article/2c34478c2ac941ffaa87116223dc7914
Publikováno v:
Ophthalmic surgery, lasersimaging retina. 51(6)
BACKGROUND AND OBJECTIVE: To evaluate disease characteristics and frequencies of genetic mutations in a cohort of patients with known or suspected retinal dystrophies. PATIENTS AND METHODS: A cohort of 37 patients with known or suspected retinal dyst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0552d2b74fa3e61c3732a8f70f2514ae
https://pubmed.ncbi.nlm.nih.gov/32579692
https://pubmed.ncbi.nlm.nih.gov/32579692
Autor:
Alan R. Sanders, Winton Moy, Jianxin Shi, Siwei Zhang, Pablo V. Gejman, Heather McGowan, Catherine Leites, Hanwen Zhang, Jubao Duan, Zhiping Pang
Publikováno v:
European Neuropsychopharmacology. 29:S799-S800
Background Allelic Imbalance of gene Expression (AIE) plays important role during neurodevelopment. However, the underlying mechanism of AIE has not been fully understood. Since chromatin accessibility (openness) has a strong influence on gene transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7edc489c836993412979def5ac039f02
https://doi.org/10.1016/j.euroneuro.2017.08.034
https://doi.org/10.1016/j.euroneuro.2017.08.034
Autor:
Heather McGowan
Publikováno v:
Journal of Neuroscience. 36:6851-6853
The epigenome consists of covalent modifications made to DNA and histones, as well as regulatory signaling mediated by RNA molecules, that result in transient, developmental, or stably inherited changes in chromatin structure and genomic function. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cde0494b7f521c130742f4bcff8c1dd9
https://doi.org/10.1523/jneurosci.1130-16.2016
https://doi.org/10.1523/jneurosci.1130-16.2016
Autor:
Winton Moy, Alan R. Sanders, Siwei Zhang, Jianxin Shi, Pablo V. Gejman, Heather McGowan, Hanwen Zhang, Jubao Duan, Catherine Leites, Zhiping P. Pang
Publikováno v:
Stem cell research
Stem Cell Research, Vol 29, Iss, Pp 88-98 (2018)
Stem Cell Research, Vol 29, Iss, Pp 88-98 (2018)
Chromatin accessibility to transcription factors (TFs) strongly influences gene transcription and cell differentiation. However, a mechanistic understanding of the transcriptional control during the neuronal differentiation of human induced pluripote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8db425747cb5fdad8b6c20a0667d4f2a
https://pubmed.ncbi.nlm.nih.gov/29631039
https://pubmed.ncbi.nlm.nih.gov/29631039
Autor:
Winton Moy, Marc P. Forrest, Jubao Duan, Zhiping P. Pang, Pablo V. Gejman, Chad A. Cowan, Heather McGowan, Jianxin Shi, Catherine Leites, Peter Penzes, William J. Greenleaf, Alan R. Sanders, Hanwen Zhang
Publikováno v:
European Neuropsychopharmacology. 29:S765
Most disease variants lie within poorly-annotated noncoding parts of the genome, and their functional interpretation is challenging. To functionally assess the relevance of noncoding sequences in neuropsychiatric disorders, we hypothesized that disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c58182c296cfabe467552dd19a38f738
https://doi.org/10.1016/j.euroneuro.2017.06.122
https://doi.org/10.1016/j.euroneuro.2017.06.122
Publikováno v:
Handbook of Anthropology in Business ISBN: 9781315427850
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab580812dfa16cd607b83c8e6a9be877
https://doi.org/10.1201/9781315427850-17
https://doi.org/10.1201/9781315427850-17
Autor:
Ronald P. Hart, Lidia De Filippis, Heather McGowan, Jennifer C. Moore, Zhiping P. Pang, Apoorva Halikere, Jay A. Tischfield
Publikováno v:
Molecular Brain
Background Alcohol abuse produces an enormous impact on health, society, and the economy. Currently, there are very limited therapies available, largely due to the poor understanding of mechanisms underlying alcohol use disorders (AUDs) in humans. Ox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3afbd537337afa550a0f1559e601212
https://pubmed.ncbi.nlm.nih.gov/27160314
https://pubmed.ncbi.nlm.nih.gov/27160314