Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Heather M. Yonutas"'
Autor:
Thomas C. Leeper, Werner J. Geldenhuys, Patrick G. Sullivan, Altaf S. Darvesh, Daniel L. Morris, Heather M. Yonutas
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:5350-5353
MitoNEET (CISD1) is a 2Fe-2S iron-sulfur cluster protein belonging to the zinc-finger protein family. Recently mitoNEET has been shown to be a major role player in the mitochondrial function associated with metabolic type diseases such as obesity and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1e0ffc46f92510fd8a5d52348ec25ae
https://doi.org/10.1016/j.bmcl.2016.09.009
https://doi.org/10.1016/j.bmcl.2016.09.009
Publikováno v:
Brain Research. 1640:77-93
Traumatic brain injury is a complicated disease to treat due to the complex multi-factorial secondary injury cascade that is initiated following the initial impact. This secondary injury cascade causes nonmechanical tissue damage, which is where ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d9dd2579ab753947863c5ae88fb18ca
https://doi.org/10.1016/j.brainres.2016.02.007
https://doi.org/10.1016/j.brainres.2016.02.007
Autor:
Werner J. Geldenhuys, Patrick G. Sullivan, Jignesh D. Pandya, Heather M. Yonutas, Hemendra J. Vekaria, W. Brad Hubbard
Publikováno v:
Exp Neurol
Mitochondrial dysfunction is a pivotal event in many neurodegenerative disease states including traumatic brain injury (TBI) and spinal cord injury (SCI). One possible mechanism driving mitochondrial dysfunction is glutamate excitotoxicity leading to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60ea4081305ce659b513ce3406b781a8
https://doi.org/10.1016/j.expneurol.2020.113243
https://doi.org/10.1016/j.expneurol.2020.113243
Autor:
Heather M. Yonutas, Samuel D. Crish, Stanley A. Benkovic, Candice M. Brown, Li Lin, Altaf S. Darvesh, Patrick G. Sullivan, Jason R. Richardson, Werner J. Geldenhuys
Mitochondrial dysfunction is thought to play a significant role in neurodegeneration observed in Parkinson's disease (PD), yet the mechanisms underlying this pathology remain unclear. Here, we demonstrate that loss of mitoNEET (CISD1), an iron-sulfur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae94327493a1ed4382cb0afa8a969a73
https://europepmc.org/articles/PMC5964979/
https://europepmc.org/articles/PMC5964979/
Changes in mitochondrial bioenergetics in the brain versus spinal cord become more apparent with age
Publikováno v:
Journal of Bioenergetics and Biomembranes. 47:149-154
The cell is known to be the most basic unit of life. However, this basic unit of life is dependent on the proper function of many intracellular organelles to thrive. One specific organelle that has vast implications on the overall health of the cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c12a571630cf9136e166906cde598b69
https://doi.org/10.1007/s10863-014-9593-5
https://doi.org/10.1007/s10863-014-9593-5
Autor:
Jenna L. VanRooyen, Heather M. Yonutas, Alexander G. Rabchevsky, Khalid C. Eldahan, David S.K. Magnuson, Patrick G. Sullivan, Jignesh D. Pandya, Samir P. Patel, Johnny R. Morehouse, Glenn A. Goldstein
Publikováno v:
Experimental Neurology. 257:95-105
Mitochondrial dysfunction is becoming a pivotal target for neuroprotective strategies following contusion spinal cord injury (SCI) and the pharmacological compounds that maintain mitochondrial function confer neuroprotection and improve long-term hin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e716861ce1e2874f8add610a02004b58
https://doi.org/10.1016/j.expneurol.2014.04.026
https://doi.org/10.1016/j.expneurol.2014.04.026
Publikováno v:
The Functions, Disease-Related Dysfunctions, and Therapeutic Targeting of Neuronal Mitochondria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58cde4ea5747e40e41008c9e5d31137e
https://doi.org/10.1002/9781119017127.ch17
https://doi.org/10.1002/9781119017127.ch17
Mitochondrial dysfunction has been linked to aging and various age-related neurodegenerative diseases within the brain. These “power plants” of the cell are essential for appropriate metabolism and energy flow within neurons, but have also been f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e716e41d820bae777eb95fe66e6cd13
https://doi.org/10.1016/b978-0-12-418680-4.00008-7
https://doi.org/10.1016/b978-0-12-418680-4.00008-7
Autor:
Claudia Aramendi, Manjeshwar Shrinath Baliga, Aysegül Bayir, Roberto Bernabei, Adam Bernstein, Harshith P. Bhat, Rekha Boloor, Esther Bravo, Riccardo Calvani, Darren G. Candow, Eva Carlsson, Thomas W. Castonguay, Jacob Chacko, Wen-Hsing Cheng, Clara K. Chow, Marshall David Colin, Agnese Collamati, Laura de Keizer, Ana Márcia Delattre, Jennifer Doley, Prajnya D’Silva, Alia El-Kadiki, Jana Barbara Ernst, Raja Fayad, Farhan Fazal, Anete Curte Ferraz, Maria Pontes Ferreira, Sebastião Rodrigues Ferreira-Filho, Scott C. Forbes, Athul Francis, Fidji Gendron, Sanjay Gupta, Mary Hägg, Raghavendra Haniadka, Elizabeth Head, Saeed Hosseini, Maite Izagirre, Ramakrishna Pai Jakribettu, Dipika Jayachander, Xiaofang Jia, Faizan Kalekhan, Kratika Kamath, Kamaljeet Kaur, Kazuya Kitamori, Wojciech Krol, Ashish Kumar, Francesco Landi, Latheesh Latheef, Silvia Maggini, Prajwal Prabhudev Mane, Tennille Marx, Emanuele Marzetti, Rashmi Teresa Mathai, Elder Betty McKenna, Katherine McLeod, Sharake Meera, Seyed-Ali Mostafavi, Hisao Naito, Tamie Nakajima, Jozy Timothy Nallemgera, George Ntaios, Saira Pais, Princy Louis Palatty, Jaclyn Palmer, Venkatesh Ponemone, Haladi Sudhir Prabhu, Manoj P. Rai, Prajwith Rai, Sahana Rao, Rithin Ravi, C.Damodar Reddy, Juli Robine, Elroy Saldanha, Arpit Saxena, Elisabetta Serafini, Arnadi Ramachandrayya Shivashankara, Paul Simon, V. Sowmya, Janmejai K. Srivastava, Pedro Vinícius Staziaki, Patrick G. Sullivan, Ewelina Szliszka, Karadka Ramdas Thilakchand, Raees Tonse, Jhansi Rani Vangavaragu, Melina Vega de Céniga, Sunitha Venkatesh, Prabhakar Vissavajjhala, Eva Sabine Wintergerst, Karl Wishart, Ryan T.Y. Wu, Husna Yetti, Heather M. Yonutas, Changhui Zhao, Armin Zittermann
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d30af133d4b405d9a3d55f48b8cb0b3e
https://doi.org/10.1016/b978-0-12-418680-4.00041-5
https://doi.org/10.1016/b978-0-12-418680-4.00041-5
Autor:
Alexander G. Rabchevsky, Glenn A. Goldstein, Samir P. Patel, James R. Pauly, Ryan D. Readnower, Jignesh D. Pandya, Patrick G. Sullivan, Heather M. Yonutas
Traumatic brain injury (TBI) has become a growing epidemic but no approved pharmacological treatment has been identified. Our previous work indicates that mitochondrial oxidative stress/damage and loss of bioenergetics play a pivotal role in neuronal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aff49d5fa98bfa3ea197e1bc869f684
https://europepmc.org/articles/PMC4086163/
https://europepmc.org/articles/PMC4086163/