Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Heather M. Duncan"'
Autor:
Meaghan Boileau, Margret Shirinian, Tenzin Gayden, Ashot S. Harutyunyan, Carol C. L. Chen, Leonie G. Mikael, Heather M. Duncan, Andrea L. Neumann, Patricia Arreba-Tutusaus, Nicolas De Jay, Michele Zeinieh, Katya Rossokhata, Yelu Zhang, Hamid Nikbakht, Carine Mouawad, Radwan Massoud, Felice Frey, Rihab Nasr, Jean El Cheikh, Marwan El Sabban, Claudia L. Kleinman, Rami Mahfouz, Mark D. Minden, Nada Jabado, Ali Bazarbachi, Kolja Eppert
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
The role of histone mutations in leukemogenesis remains largely unexplored. In this study of AML, the authors show that histone mutations are early events that drive a more aggressive phenotype.
Externí odkaz:
https://doaj.org/article/c65cab72003240578c7b04815c5c955e
Autor:
Siham Sabri, Bertrand Jean-Claude, Marie-Christine Guiot, Kevin Petrecca, Heather M. Duncan, Kolja Eppert, Nidia Lauzon, Julie Schmitt, Paul Daniel, Janusz Rak, Brian Meehan, Bassam Abdulkarim, Zeinab Sharifi
Table S2 summarizes IC50s of TMZ, gefitinib or ZR2002 for various GSCs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08c4de5f08c4018da23d11fe7fb26034
https://doi.org/10.1158/1078-0432.22472120.v1
https://doi.org/10.1158/1078-0432.22472120.v1
Autor:
Siham Sabri, Bertrand Jean-Claude, Marie-Christine Guiot, Kevin Petrecca, Heather M. Duncan, Kolja Eppert, Nidia Lauzon, Julie Schmitt, Paul Daniel, Janusz Rak, Brian Meehan, Bassam Abdulkarim, Zeinab Sharifi
Figure S3 shows ZR2002 alternate (schedule#1) or continuous (schedule#2) treatment protocol (A) and monitoring mice body weights for alternate (B) or continuous (C) treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05f20b5817416bb837626e4099226033
https://doi.org/10.1158/1078-0432.22472132
https://doi.org/10.1158/1078-0432.22472132
Autor:
Siham Sabri, Bertrand Jean-Claude, Marie-Christine Guiot, Kevin Petrecca, Heather M. Duncan, Kolja Eppert, Nidia Lauzon, Julie Schmitt, Paul Daniel, Janusz Rak, Brian Meehan, Bassam Abdulkarim, Zeinab Sharifi
Supplementary Legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b0131ca621e7244aa5c582176b5369
https://doi.org/10.1158/1078-0432.22472126
https://doi.org/10.1158/1078-0432.22472126
Autor:
Siham Sabri, Bertrand Jean-Claude, Marie-Christine Guiot, Kevin Petrecca, Heather M. Duncan, Kolja Eppert, Nidia Lauzon, Julie Schmitt, Paul Daniel, Janusz Rak, Brian Meehan, Bassam Abdulkarim, Zeinab Sharifi
Figure S7 provides evidence for the presence and co-localization of ZR2002 with its dealkylated metabolite ZR01, a potent EGFR inhibitor using MALDI IMS in brain tumor tissue.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::922e5850783872b962b688afb8a85a81
https://doi.org/10.1158/1078-0432.22472141
https://doi.org/10.1158/1078-0432.22472141
Autor:
Siham Sabri, Bertrand Jean-Claude, Marie-Christine Guiot, Kevin Petrecca, Heather M. Duncan, Kolja Eppert, Nidia Lauzon, Julie Schmitt, Paul Daniel, Janusz Rak, Brian Meehan, Bassam Abdulkarim, Zeinab Sharifi
Purpose:Glioblastoma (GBM) is a fatal primary malignant brain tumor. GBM stem cells (GSC) contribute to resistance to the DNA-damaging chemotherapy, temozolomide. The epidermal growth factor receptor (EGFR) displays genomic alterations enabling DNA r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bacf8100c0c38c8fb480e4553dfc6c39
https://doi.org/10.1158/1078-0432.c.6528128
https://doi.org/10.1158/1078-0432.c.6528128
Autor:
Siham Sabri, Bertrand Jean-Claude, Marie-Christine Guiot, Kevin Petrecca, Heather M. Duncan, Kolja Eppert, Nidia Lauzon, Julie Schmitt, Paul Daniel, Janusz Rak, Brian Meehan, Bassam Abdulkarim, Zeinab Sharifi
Figure S6 shows quantitative analysis of the proliferation marker Ki-67 by immunohistochemical staining of brain tumor tissue collected from mice with orthotopic 1123IC7R tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::890d1d0301f43816a4c36ce8b5887dbb
https://doi.org/10.1158/1078-0432.22472144.v1
https://doi.org/10.1158/1078-0432.22472144.v1
Autor:
Siham Sabri, Bertrand Jean-Claude, Marie-Christine Guiot, Kevin Petrecca, Heather M. Duncan, Kolja Eppert, Nidia Lauzon, Julie Schmitt, Paul Daniel, Janusz Rak, Brian Meehan, Bassam Abdulkarim, Zeinab Sharifi
Figure S5 shows additional MALDI imaging mass spectrometry (MALDI IMS) data to confirm the presence of ZR2002 in brain tumor tissue.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6f7d216b7d268390f25c0e446de2d04
https://doi.org/10.1158/1078-0432.22472147
https://doi.org/10.1158/1078-0432.22472147
Publikováno v:
Open Forum Infectious Diseases
Background Significant antimicrobial use occurs in outpatient settings, making this an important area for expanding stewardship. Data show over 260 million annual prescriptions in the U.S. Family practitioners prescribed the most antibiotic courses (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8efb230f38153ecf3aaaf389fa0a84f0
https://doi.org/10.1093/ofid/ofaa439.183
https://doi.org/10.1093/ofid/ofaa439.183
Autor:
Rami Mahfouz, Rihab Nasr, Tenzin Gayden, Ashot S. Harutyunyan, Carol X.-Q. Chen, Nada Jabado, Michele Zeinieh, Patricia Arreba-Tutusaus, Felice Frey, Meaghan Boileau, Hamid Nikbakht, Heather M. Duncan, Kolja Eppert, Marwan El Sabban, Nicolas De Jay, Margret Shirinian, Jean El Cheikh, Claudia L. Kleinman, Carine Mouawad, Ali Bazarbachi, Radwan Massoud, Andrea Neumann, Mark D. Minden, Leonie G. Mikael
Publikováno v:
Experimental Hematology. 64:S55-S56
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a32444770a50e48fc79b9eea851094bb
https://doi.org/10.1016/j.exphem.2018.06.195
https://doi.org/10.1016/j.exphem.2018.06.195