Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Heather M Sonnemann"'
Autor:
Yan Zhang, Zhenglu Wang, Cassian Yee, Patrick Hwu, Chantale Bernatchez, Jason Roszik, Roland Bassett, Marie-Andree Forget, Minying Zhang, Michael A Davies, Gregory Lizee, Ling Han, Fenge Li, Ligang Deng, Kyle R Jackson, Amjad H Talukder, Arjun S Katailiha, Sherille D Bradley, Qingwei Zou, Caixia Chen, Chong Huo, Yulun Chiu, Matthew Stair, Weihong Feng, Aleksander Bagaev, Nikita Kotlov, Viktor Svekolkin, Ravshan Ataullakhanov, Natalia Miheecheva, Felix Frenkel, Yaling Wang, David Hawke, Shuo Zhou, William K Decker, Heather M Sonnemann, Xueming Du
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
Background Neoantigen (NeoAg) peptides displayed at the tumor cell surface by human leukocyte antigen molecules show exquisite tumor specificity and can elicit T cell mediated tumor rejection. However, few NeoAgs are predicted to be shared between pa
Externí odkaz:
https://doaj.org/article/ac1fa606444a418b80b726080cf67799
Autor:
Heather M. Sonnemann, Barbara Pazdrak, Barbara Nassif, Yimo Sun, Lama Elzohary, Amjad H. Talukder, Arjun S. Katailiha, Krishna Bhat, Gregory Lizée
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionVestigial-like 1 (VGLL1) is a co-transcriptional activator that binds to TEA domain-containing transcription factors (TEADs). Its expression is upregulated in a variety of aggressive cancer types, including pancreatic and basal-like breas
Externí odkaz:
https://doaj.org/article/d25bbf27559a40dbbe381989efdb6b3e
Autor:
Amber J. Giles, Marsha-Kay N. D. Hutchinson, Heather M. Sonnemann, Jinkyu Jung, Peter E. Fecci, Nivedita M. Ratnam, Wei Zhang, Hua Song, Rolanda Bailey, Dionne Davis, Caitlin M. Reid, Deric M. Park, Mark R. Gilbert
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-13 (2018)
Abstract Background Corticosteroids are routinely utilized to alleviate edema in patients with intracranial lesions and are first-line agents to combat immune-related adverse events (irAEs) that arise with immune checkpoint blockade treatment. Howeve
Externí odkaz:
https://doaj.org/article/dbbd8ceab8b343afa6a998b078f2f24a
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer. 1878:188892
Autor:
Barbara Pazdrak, Heather M. Sonnemann, Salah-Eddine Bentebibel, Barbara M. Nassif, Greg Lizee, Adi Diab
Publikováno v:
Cancer Research. 83:5079-5079
Agonistic CD40 antibodies have shown promise when used in combination with checkpoint inhibitors in clinical trials for the treatment of malignancies. However, the mechanisms driving antitumor immune responses in patients are not well understood. The
Autor:
Hervé Tiriac, Heather M. Sonnemann, Ivy Lai, Jason Roszik, Christopher A. Bristow, Minying Zhang, David A. Tuveson, Patrick Hwu, Robert A. Wolff, Fenge Li, Brenda Melendez, Christine B. Peterson, Bih Fang Pan, Arjun S. Katailiha, Michael P. Kim, Cassian Yee, Amjad H. Talukder, Philip L. Lorenzi, Yulun Chiu, Anirban Maitra, Milind Javle, Scott Kopetz, Mark W. Hurd, Na Qiao, David H. Hawke, Gregory Lizée, Rebecca Davis, Elizabeth A. Mittendorf, Kyle R. Jackson, Sherille D. Bradley, Ya'an Kang, Héctor M. Alvarez
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications
Cytotoxic T lymphocyte (CTL)-based cancer immunotherapies have shown great promise for inducing clinical regressions by targeting tumor-associated antigens (TAA). To expand the TAA landscape of pancreatic ductal adenocarcinoma (PDAC), we performed ta
Autor:
Kyle R Jackson, Dinler A Antunes, Amjad H Talukder, Ariana R Maleki, Kano Amagai, Avery Salmon, Arjun S Katailiha, Yulun Chiu, Romanos Fasoulis, Maurício Menegatti Rigo, Jayvee R Abella, Brenda D Melendez, Fenge Li, Yimo Sun, Heather M Sonnemann, Vladislav Belousov, Felix Frenkel, Sune Justesen, Aman Makaju, Yang Liu, David Horn, Daniel Lopez-Ferrer, Andreas F Huhmer, Patrick Hwu, Jason Roszik, David Hawke, Lydia E Kavraki, Gregory Lizée
Publikováno v:
PNAS nexus. 1(3)
Human leukocyte antigen class I (HLA-I) molecules bind and present peptides at the cell surface to facilitate the induction of appropriate CD8+ T cell-mediated immune responses to pathogen- and self-derived proteins. The HLA-I peptide-binding cleft c
Autor:
Yimo Sun, Kyle R. Jackson, Amjad H. Talukder, Fenge Li, Arjun S. Katailiha, Gregory Lizée, Heather M. Sonnemann
Publikováno v:
Cells, Vol 10, Iss 2379, p 2379 (2021)
Engineered T cell receptor T (TCR-T) cell therapy has facilitated the generation of increasingly reliable tumor antigen-specific adaptable cellular products for the treatment of human cancer. TCR-T cell therapies were initially focused on targeting s
Autor:
Zou Qingwei, Ling Han, William K. Decker, Chong Huo, Nikita Kotlov, Michael A. Davies, Cassian Yee, David H. Hawke, Kyle R. Jackson, Gregory Lizée, Caixia Chen, Shuo Zhou, Arjun S. Katailiha, Zhenglu Wang, Deng Ligang, Chantale Bernatchez, Amjad H. Talukder, Wang Yaling, Yulun Chiu, Minying Zhang, Natalia Miheecheva, Felix Frenkel, Matthew Stair, Yan Zhang, Weihong Feng, Jason Roszik, Xueming Du, Patrick Hwu, Aleksander Bagaev, Marie Andrée Forget, Sherille D. Bradley, Roland L. Bassett, Viktor Svekolkin, Ataullakhanov Ravshan I, Fenge Li, Heather M. Sonnemann
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
BackgroundNeoantigen (NeoAg) peptides displayed at the tumor cell surface by human leukocyte antigen molecules show exquisite tumor specificity and can elicit T cell mediated tumor rejection. However, few NeoAgs are predicted to be shared between pat
Publikováno v:
Cancer Immunology Research. 8:B5-B5
Glioblastoma (GBM) is a lethal brain malignancy, and standard of care only offers a modest survival benefit. Emerging evidence of immune surveillance in the brain has prompted investigation of immunotherapy as a potential treatment strategy. However,