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pro vyhledávání: '"Heather M, Hager"'
Autor:
Bing X. Ross, Lin Jia, Dejuan Kong, Tiantian Wang, Heather M. Hager, Steven F. Abcouwer, David N. Zacks
Publikováno v:
Cells, Vol 10, Iss 8, p 2010 (2021)
After retinal detachment (RD), the induction of autophagy protects photoreceptors (PR) from apoptotic cell death. The cytoplasmic high-mobility group box 1 (HMGB1) promotes autophagy. We previously demonstrated that the deletion of HMGB1 from rod PRs
Externí odkaz:
https://doaj.org/article/53b1126dcf584204b32b40395a0911cf
Autor:
Bing X, Ross, Lin, Jia, Dejuan, Kong, Tiantian, Wang, Jingyu, Yao, Heather M, Hager, Steven F, Abcouwer, David N, Zacks
Publikováno v:
Investigative Opthalmology & Visual Science. 63:7
Following retinal detachment (RD) photoreceptors (PRs) sustain hypoxic stress and eventually die. Hypoxia-inducible factor-1α (HIF-1α) plays a central role in cellular adaptation to hypoxia. The purpose of this study is to determine the necessity o