Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Heather M, Clark"'
Autor:
Neha Singh-Reilly, Hugo Botha, Joseph R. Duffy, Heather M. Clark, Rene L. Utianski, Mary M. Machulda, Jonathan Graff-Radford, Christopher G. Schwarz, Ronald C. Petersen, Val J. Lowe, Clifford R. Jack, Jr, Keith A. Josephs, Jennifer L. Whitwell
Publikováno v:
NeuroImage: Clinical, Vol 43, Iss , Pp 103639- (2024)
Primary progressive aphasia (PPA) variants present with distinct disruptions in speech-language functions with little known about the interplay between affected and spared regions within the speech-language network and their interaction with other fu
Externí odkaz:
https://doaj.org/article/67ce0fdfcf9a4894abf06efac9019079
Autor:
Rodolfo G. Gatto, Gabriela Meade, Joseph R. Duffy, Heather M. Clark, Rene L. Utianski, Hugo Botha, Mary M. Machulda, Keith A. Josephs, Jennifer L. Whitwell
Publikováno v:
Brain and Behavior, Vol 14, Iss 1, Pp n/a-n/a (2024)
Abstract Background Progressive apraxia of speech (PAOS) is characterized by difficulties with motor speech programming and planning. PAOS targets gray matter (GM) and white matter (WM) microstructure that can be assessed using diffusion tensor imagi
Externí odkaz:
https://doaj.org/article/76e850b7928443e58ea7ca7b4898c7b1
Autor:
Rene L. Utianski, Nha Trang Thu Pham, Hugo Botha, Farwa Ali, Joseph R. Duffy, Heather M. Clark, Val J. Lowe, Jennifer L. Whitwell, Keith A. Josephs
Publikováno v:
Clinical Parkinsonism & Related Disorders, Vol 9, Iss , Pp 100207- (2023)
Purpose: To describe qualitative and quantitative longitudinal changes in dopamine transporter uptake (DaT) scan findings in progressive apraxia of speech (PAOS) patients. Methods: DaTQUANT software was used to quantify uptake in the left and right c
Externí odkaz:
https://doaj.org/article/41a2f20f8d6c4e2b8bc2e7a7ce5b2f7e
Autor:
Ryota Satoh, Arvin Arani, Matthew L. Senjem, Joseph R. Duffy, Heather M. Clark, Rene L. Utianski, Hugo Botha, Mary M. Machulda, Clifford R. Jack, Jr, Jennifer L. Whitwell, Keith A. Josephs
Publikováno v:
NeuroImage: Clinical, Vol 38, Iss , Pp 103394- (2023)
Purpose: Progressive apraxia of speech (PAOS) is a neurodegenerative disorder affecting the planning or programming of speech. Little is known about its magnetic susceptibility profiles indicative of biological processes such as iron deposition and d
Externí odkaz:
https://doaj.org/article/4d00bd1c46ae429f9dee536a53657ed4
Autor:
Keith A. Josephs, Joseph R. Duffy, Heather M. Clark, Rene L. Utianski, Edythe A. Strand, Mary M. Machulda, Hugo Botha, Peter R. Martin, Nha Trang Thu Pham, Julie Stierwalt, Farwa Ali, Marina Buciuc, Matthew Baker, Cristhoper H. Fernandez De Castro, Anthony J. Spychalla, Christopher G. Schwarz, Robert I. Reid, Matthew L. Senjem, Clifford R. Jack, Val J. Lowe, Eileen H. Bigio, Ross R. Reichard, Eric. J. Polley, Nilufer Ertekin-Taner, Rosa Rademakers, Michael A. DeTure, Owen A. Ross, Dennis W. Dickson, Jennifer L. Whitwell
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Progressive apraxia of speech (PAOS) is a neurodegenerative syndrome of multiple etiologies which affects spoken communication. Here, the authors characterized the molecular pathology, biochemistry, genetics and longitudinal neuroimaging of 32 autops
Externí odkaz:
https://doaj.org/article/ed3e8ba520e446b7a84a4834659451e7
Autor:
Zafer Keser, Samuel C. Buchl, Nathan A. Seven, Matej Markota, Heather M. Clark, David T. Jones, Giuseppe Lanzino, Robert D. Brown, Gregory A. Worrell, Brian N. Lundstrom
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Stroke is one of the leading causes of death and disability. Despite the high prevalence of stroke, characterizing the acute neural recovery patterns that follow stroke and predicting long-term recovery remains challenging. Objective methods to quant
Externí odkaz:
https://doaj.org/article/4ed4cd52b6a44ad8bead84eb1929f487
Autor:
Rodolfo G. Gatto, Peter R. Martin, Farwa Ali, Heather M. Clark, Joseph R. Duffy, Rene L. Utianski, Hugo Botha, Mary M. Machulda, Dennis W. Dickson, Keith A. Josephs, Jennifer L. Whitwell
Publikováno v:
NeuroImage: Clinical, Vol 35, Iss , Pp 103030- (2022)
Background: Progressive supranuclear palsy (PSP) is a 4-repeat tauopathy with neurodegeneration typically observed in the superior cerebellar peduncle (SCP) and dentatorubrothalamic tracts (DRTT). However, it is unclear how these tracts are different
Externí odkaz:
https://doaj.org/article/1116345c829049db8a6f035fb194df94
Autor:
Adrian Valls Carbo, Robert I. Reid, Nirubol Tosakulwong, Stephen D. Weigand, Joseph R. Duffy, Heather M. Clark, Rene L. Utianski, Hugo Botha, Mary M. Machulda, Edythe A. Strand, Christopher G. Schwarz, Clifford R. Jack, Keith A. Josephs, Jennifer L. Whitwell
Publikováno v:
NeuroImage: Clinical, Vol 34, Iss , Pp 102999- (2022)
Progressive apraxia of speech (AOS) is a motor speech disorder affecting the ability to produce phonetically or prosodically normal speech. Progressive AOS can present in isolation or co-occur with agrammatic aphasia and is associated with degenerati
Externí odkaz:
https://doaj.org/article/e5c8ec5b7d01419ba5f0e1ad64cc6823
Autor:
Joseph R. Duffy, Peter R. Martin, Heather M. Clark, Rene L. Utianski, Edythe A. Strand, Jennifer L. Whitwell, Keith A. Josephs
Publikováno v:
American Journal of Speech-Language Pathology. 32:469-491
Purpose: The purpose of this study was to examine the interrater reliability and validity of the Apraxia of Speech Rating Scale (ASRS-3.5) as an index of the presence and severity of apraxia of speech (AOS) and the prominence of several of its import
Autor:
Rene L. Utianski, Joseph R. Duffy, Peter R. Martin, Heather M. Clark, Julie A. G. Stierwalt, Hugo Botha, Farwa Ali, Jennifer L. Whitwell, Keith A. Josephs
Publikováno v:
Journal of Speech, Language, and Hearing Research. :1-12
Purpose: The purpose of this study was to describe, compare, and understand speech modulation capabilities of patients with varying motor speech disorders (MSDs) in a paradigm in which patients made highly cued attempts to speak faster or slower. Met