Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Heather L. Patney"'
Autor:
Heather L. Patney, Brad Love, Darrell L. Ellsworth, Jeffrey A. Hooke, Rachel E. Ellsworth, Craig D. Shriver, Brenda Deyarmin
Publikováno v:
Annals of Surgical Oncology. 15:1989-1995
Molecular studies suggest that acquisition of metastatic potential occurs early in the development of breast cancer; mechanisms by which cells disseminate from the primary carcinomas and successfully colonize foreign tissues are, however, largely unk
Autor:
Darrell L. Ellsworth, L.M. Voeghtly, A. Burke, M.J. Haberkorn, David J. Decewicz, D.M. Neatrour, Marina N. Vernalis, Heather L. Patney, F. Lechak
Publikováno v:
Nutrition, metabolism, and cardiovascular diseases : NMCD. 23(7)
Insulin and leptin are important markers of insulin resistance and vascular inflammation in metabolic and cardiovascular diseases. This study evaluated changes in circulating levels of insulin and leptin during a cardiovascular health program to impr
Autor:
Amy Burke, Darrell L. Ellsworth, David J. Decewicz, Mary Jane Haberkorn, David M. Neatrour, Heather L. Patney, Marina N. Vernalis
Publikováno v:
Lipids in Health and Disease
Lipids in Health and Disease, Vol 8, Iss 1, p 26 (2009)
Lipids in Health and Disease, Vol 8, Iss 1, p 26 (2009)
Background Low-density lipoprotein (LDL) cholesterol lowering is a primary goal in clinical management of patients with cardiovascular disease, but traditional cholesterol levels may not accurately reflect the true atherogenicity of plasma lipid prof
Autor:
Craig D. Shriver, Rachel E. Ellsworth, Brenda Deyarmin, Jeffrey A. Hooke, Brad Love, Darrell L. Ellsworth, Heather L. Patney
Publikováno v:
BMC Cancer, Vol 8, Iss 1, p 297 (2008)
BMC Cancer
BMC Cancer
Background Genomic alterations of the proto-oncogene c-erbB-2 (HER-2/neu) are associated with aggressive behavior and poor prognosis in patients with breast cancer. The variable clinical outcomes seen in patients with similar HER2 status, given simil
Autor:
Marina N. Vernalis, Daniel T. Croft, Craig D. Shriver, Trevor J. Orchard, Heather L. Patney, Rick Jordan, Darrell L. Ellsworth
Publikováno v:
The Journal of molecular diagnostics : JMD. 10(3)
Defining genetic variation associated with complex human diseases requires standards based on high-quality DNA from well-characterized patients. With the development of robust technologies for whole-genome amplification, sample repositories such as s
Autor:
Craig D. Shriver, Jeffrey A. Hooke, Rachel E. Ellsworth, Heather L. Patney, Rick Jordan, Darrell L. Ellsworth, T. E. Becker, Brenda Deyarmin
Publikováno v:
Annals of surgical oncology. 15(4)
Metastatic breast cancer is an aggressive disease associated with recurrence and decreased survival. To improve outcomes and develop more effective treatment strategies for patients with breast cancer, it is important to understand the molecular mech
Autor:
Craig D. Shriver, Jeffrey A. Hooke, Darrell L. Ellsworth, Rachel E. Ellsworth, Heather L. Patney, Laurel R. Hoffman, Jennifer Kane, Brad Love
Publikováno v:
Annals of surgical oncology. 14(11)
Histological grading of ductal carcinoma-in-situ (DCIS) lesions separates DCIS into three subgroups (well-, moderately, or poorly differentiated). It is unclear, however, whether breast disease progresses along a histological continuum or whether eac
Autor:
Heather L. Patney, Jeffrey A. Hooke, Brad Love, Craig D. Shriver, Rachel E. Ellsworth, Jennifer Kane, Darrell L. Ellsworth
Publikováno v:
Breast cancer research and treatment. 107(2)
Pathological grade is a useful prognostic factor for stratifying breast cancer patients into favorable (well-differentiated tumors) and less favorable (poorly-differentiated tumors) outcome groups. The current system of tumor grading, however, is sub
Autor:
Heather L. Patney, H Dang, K Ellison, RE Ellsworth, Craig D. Shriver, Martin Rosman, Lorraine Tafra, Brenda Deyarmin, Z Cheng, JD Thornton
Publikováno v:
Cancer Research. 70:P6-04
Background: Treatment options for DCIS vary from surgical excision with or without radiation and/or chemopreventive therapy, or mastectomy. Intuitively, more aggressive treatment options should lead to improved survival rates, however, studies have s
Publikováno v:
Cancer Research. 70:2134-2134
Objective Histological grade classifies breast carcinomas into low-, intermediate- and high-grade. Developmental pathways for high-grade disease remain controversial; clinical data have been used to describe both linear models, in which high-grade tu