Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Heather L. Lawson"'
Publikováno v:
Blood Coagulation & Fibrinolysis. 17:673-675
Spontaneous bleeding in adults is a major problem, and in a significant number of these patients no cause is found. A 63-year-old Caucasian man presented to our hematology clinic with a large hematoma of his left thigh. Initial investigations did not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c5fb954e9478c384986dff56244e371
https://doi.org/10.1097/mbc.0b013e3280108e1a
https://doi.org/10.1097/mbc.0b013e3280108e1a
Autor:
Heather L. Lawson, Lin Zhang, Vallathucherry C. Harish, Jason D. Huff, John Owen, Mary Ann Knovich
Publikováno v:
Analytical biochemistry. 358(2)
based assays. Generation of pure, reliable,high-quality substrate is essential to such assays. SmallFRET substrates can be easily prepared by chemical pro-duction. The preparation of Xuorogenic substrate becomescumbersome when a larger peptide substr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf53d13a086424c1fcabb5eea659f007
https://pubmed.ncbi.nlm.nih.gov/16876104
https://pubmed.ncbi.nlm.nih.gov/16876104
Publikováno v:
American journal of hematology. 76(3)
The absence of VWF cleaving protease activity (VWFcp, ADAMTS13) has recently been identified as a central component in the pathogenesis of TTP. Several assays for the measurement of ADAMTS13 activity have been described, but most are cumbersome and e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::316b8366e6020f93588492d60c46a0cc
https://pubmed.ncbi.nlm.nih.gov/15224369
https://pubmed.ncbi.nlm.nih.gov/15224369
Publikováno v:
Blood. 108:4040-4040
ADAMTS13 (von Willebrand Factor cleaving protease) is a zinc metalloprotease that cleaves the Tyr(1605)/Met(1606) bond within the A2 domain of von Willebrand Factor (vWF). Low levels of ADAMTS13 activity ( Present methods for measuring ADAMTS13 activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::474161e3dc27c21cdb9fbc1fd0cdec58
https://doi.org/10.1182/blood.v108.11.4040.4040
https://doi.org/10.1182/blood.v108.11.4040.4040
Publikováno v:
Blood. 106:4062-4062
Spontaneous disruption of hemostasis in adults is a common clinical presentation. However, in a few patients, no cause is found. We were faced with such a situation when a 63 year old Caucasian male presented with a large spontaneous hematoma of his
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b9f7bd663cf6993fe3e5d5bf5bc75c9
https://doi.org/10.1182/blood.v106.11.4062.4062
https://doi.org/10.1182/blood.v106.11.4062.4062
Publikováno v:
Blood. 106:4146-4146
Warfarin resistance is a common clinical problem encountered by physicians of all subspecialities. Medical noncompliance and dietary indiscretions are felt to be the usual causes of a subject’s “resistance” to anticoagulation with coumarin deri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::647436a879b930334b1bcefb110ceb71
https://doi.org/10.1182/blood.v106.11.4146.4146
https://doi.org/10.1182/blood.v106.11.4146.4146
Autor:
Lin Zhang, Vallathucherry C. Harish, John Owen, Heather L. Lawson, Jason D. Huff, Mary Ann Knovich
Publikováno v:
Blood. 106:3941-3941
Proteases are enzymes that catalyze the breakdown of peptide bonds. They are essential to all physiologic and pathological processes. Some protease deficiencies are closely associated with certain disease conditions, such as alpha-1-Antitrypsin defic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e81c2d4224d08fb0e4df03a0a331c30
https://doi.org/10.1182/blood.v106.11.3941.3941
https://doi.org/10.1182/blood.v106.11.3941.3941