Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Heather L. Gardner"'
Autor:
Gretchen P. McLinden, Anne C. Avery, Heather L. Gardner, Kelly Hughes, Angie M. Rodday, Kexuan Liang, Cheryl A. London
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 38, Iss 3, Pp 1666-1674 (2024)
Abstract Background To explore the safety and utility of combining low dose single‐agent doxorubicin with a canine specific anti‐CD20 monoclonal antibody (1E4‐cIgGB) in client owned dogs with untreated B‐cell lymphoma. Animals Forty‐two cli
Externí odkaz:
https://doaj.org/article/298dea408eb844359dba10c2e4026ea5
Autor:
Jadesola Temitope Olayinka, Akanksha Nagarkar, Diana Junyue Ma, Neil B. Wong, Andrew Romasco, Cesar Piedra-Mora, Linda Wrijil, Clement N. David, Heather L. Gardner, Nicholas A. Robinson, Kelly L. Hughes, Bruce Barton, Cheryl A. London, Ramón M. Almela, Jillian M. Richmond
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
Cutaneous T-cell lymphoma (CTCL) is an uncommon type of lymphoma involving malignant skin-resident or skin-homing T cells. Canine epitheliotropic lymphoma (EL) is the most common form of CTCL in dogs, and it also spontaneously arises from T lymphocyt
Externí odkaz:
https://doaj.org/article/073a508055a14180ac8f458d7bea2ad7
Publikováno v:
BMC Veterinary Research, Vol 15, Iss 1, Pp 1-7 (2019)
Abstract Background Oclacitinib is an orally bioavailable Janus Kinase (JAK) inhibitor approved for the treatment of canine atopic dermatitis. Aberrant JAK/ Signal Transducer and Activator of Transcription (STAT) signaling within hematologic and soli
Externí odkaz:
https://doaj.org/article/b3540c6a70c34a788966a76f1d284b6d
Autor:
Abbey R. Sadowski, Heather L. Gardner, Antonella Borgatti, Heather Wilson, David M. Vail, Joshua Lachowicz, Christina Manley, Avenelle Turner, Mary K. Klein, Angharad Waite, Alexandra Sahora, Cheryl A. London
Publikováno v:
BMC Veterinary Research, Vol 14, Iss 1, Pp 1-7 (2018)
Abstract Background Chemotherapeutic options for the treatment of canine lymphoma have not changed in several decades necessitating the identification of new therapeutics to improve patient outcome. KPT-335 (verdinexor) is a novel orally bioavailable
Externí odkaz:
https://doaj.org/article/5970ac9c08524ac99e1ae4efc81b1bbf
Publikováno v:
BMC Veterinary Research, Vol 13, Iss 1, Pp 1-9 (2017)
Abstract Background Hyperthermia is an established anti-cancer treatment but is limited by tolerance of adjacent normal tissues. Parenteral administration of gold nanorods (NRs) as a photosensitizer amplifies the effects of hyperthermia treatment whi
Externí odkaz:
https://doaj.org/article/b27046c549ba4175a137265793bd37a0
Autor:
Katherine Dittrich, Ümmügülsüm Yıldız-Altay, Fatima Qutab, Danny A Kwong, Zechuan Rao, Sebastian A Nievez-Lozano, Heather L Gardner, Jillian M Richmond, Cheryl A London
Publikováno v:
PLoS ONE, Vol 18, Iss 8, p e0290428 (2023)
Pet dogs develop spontaneous diffuse large B cell lymphoma (DLBCL), and veterinary clinical trials have been employed to treat canine DLBCL and to inform clinical trials for their human companions. A challenge that remains is selection of treatment t
Externí odkaz:
https://doaj.org/article/c3e092a2d8ea4b18bd9e6af5fc3eab48
Autor:
Kate Megquier, Jason Turner-Maier, Kathleen Morrill, Xue Li, Jeremy Johnson, Elinor K Karlsson, Cheryl A London, Heather L Gardner
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0274383 (2022)
The characterization of immortalized canine osteosarcoma (OS) cell lines used for research has historically been based on phenotypic features such as cellular morphology and expression of bone specific markers. With the increasing use of these cell l
Externí odkaz:
https://doaj.org/article/141e55c5532a44ba85cdda09c7b40708
Autor:
David A. Proia, Sandra A. Bechtel, Misty D. Bear, Louis Feo Bernabe, Heather L. Gardner, Luisa Shin Ogawa, Manuel Sequeira, Donald L. Smith, Jaime Acquaviva, Cheryl A. London
Purpose:STA-1474, prodrug of the heat shock protein 90 inhibitor (HSP90i) ganetespib, previously demonstrated activity in canine preclinical models of cancer; interestingly, prolonged infusions were associated with improved biologic activity. The pur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b22b757a6ae0102c9886c0aa906249
https://doi.org/10.1158/1078-0432.c.6527022.v1
https://doi.org/10.1158/1078-0432.c.6527022.v1
Autor:
David A. Proia, Sandra A. Bechtel, Misty D. Bear, Louis Feo Bernabe, Heather L. Gardner, Luisa Shin Ogawa, Manuel Sequeira, Donald L. Smith, Jaime Acquaviva, Cheryl A. London
Supplementary Table 1: Adverse Events
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5da1ba8b3f89da568685e6906fa90364
https://doi.org/10.1158/1078-0432.22468650
https://doi.org/10.1158/1078-0432.22468650
Autor:
Richard Gedrich, Theresa M. LaVallee, Gerald McMahon, Andrew J. Garton, Lori Lopresti-Morrow, Linda Crew, Krista La Perle, Gerald Post, Sarah Rippy, Heather L. Gardner, Cheryl A. London
Serum KTN0158 concentration over time
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f2cb449b9959ba6fe9bf6b2fea2e4da
https://doi.org/10.1158/1078-0432.22467360
https://doi.org/10.1158/1078-0432.22467360