Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Heather L. Davis"'
Autor:
Jennifer M. Thorn, Keshab Bhattacharya, Renata Crutcher, Justin Sperry, Colleen Isele, Barbara Kelly, Libbey Yates, James Zobel, Ningli Zhang, Heather L. Davis, Michael J. McCluskie
Publikováno v:
Vaccines, Vol 5, Iss 2, p 11 (2017)
Smoking remains one of the major causes of morbidity and mortality worldwide. One approach to assisting smoking cessation is via anti-nicotine vaccines, composed of nicotine-like haptens conjugated to a carrier protein plus adjuvant(s). We have previ
Externí odkaz:
https://doaj.org/article/c9bde9921e754ec989c485e11d57098d
Publikováno v:
Vaccines, Vol 4, Iss 2, p 14 (2016)
Endosomal Toll-like receptors (TLR) such as TLR3, 7, 8 and 9 recognize pathogen associated nucleic acids. While DNA sequence does influence degree of binding to and activation of TLR9, it also appears to influence the ability of the ligand to reach t
Externí odkaz:
https://doaj.org/article/1a4951b0392c4b94986a5382708cbae1
Autor:
Bassel Akache, Risini D. Weeratna, Aparna Deora, Jennifer M. Thorn, Brian Champion, James R. Merson, Heather L. Davis, Michael J. McCluskie
Publikováno v:
Vaccines, Vol 4, Iss 1, p 3 (2016)
Qb bacteriophage virus-like particles (Qb-VLP) are utilized as carriers to enhance immune responses to weakly or non-immunogenic antigens such as peptides and haptens. Qb-VLPs are formed through the self-assembly of multiple Qb capsid protein monomer
Externí odkaz:
https://doaj.org/article/7eeef5d9221c4965aaafaaaedea31041
Autor:
Heather L. Davis
Publikováno v:
Nerve-Muscle Cell Trophic Communication ISBN: 9780429282430
Nerve-Muscle Cell Trophic Communication
Nerve-Muscle Cell Trophic Communication
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8eb158223cc7b70d0d134d1ac1c1ae71
https://doi.org/10.1201/9780429282430-7
https://doi.org/10.1201/9780429282430-7
Publikováno v:
International Immunology. 28:453-461
Adjuvants are a key component in enhancing immunogenicity of vaccines and play a vital role in facilitating the induction of the correct type of immunity required for each vaccine to be optimally efficacious. Several different adjuvants are found in
Autor:
Heather L. Davis, Brian Robert Champion, Ghania Chikh, James D. Fraser, Lu Zhang, James R. Merson, Michael J. McCluskie, Jennifer Marie Thorn, Risini D. Weeratna
Publikováno v:
Immunity, Inflammation and Disease
The anti‐human immunoglobulin E (IgE) monoclonal antibody, omalizumab (Xolair®, Genentech, South San Fransisco, CA), is effective in the treatment of poorly controlled moderate to severe allergic asthma and chronic idiopathic urticaria. It acts by
Autor:
Ejuan Zhang, Thekla Kemper, Mengji Lu, Jörg Vollmer, Wolfram H. Gerlich, Michael Roggendorf, Xiaoyong Zhang, Rongjuan Pei, Dieter Glebe, Heather L. Davis, Zhongji Meng
Publikováno v:
Antiviral Research. 125:14-24
CpG oligodeoxynucleotides (ODNs) stimulate immune cells via TLR9 and are potentially useful immunomodulators for the treatment of chronic viral infections. In the present study, different classes of CpGs were tested for their capacities for innate im
Autor:
James F. Zobel, Libbey Anne Yates, Jennifer Marie Thorn, Colleen Isele, Michael J. McCluskie, Keshab Bhattacharya, Justin B. Sperry, Renata Crutcher, Barbara Kelly, Ningli Zhang, Heather L. Davis
Publikováno v:
Vaccines, Vol 5, Iss 2, p 11 (2017)
Vaccines
Vaccines
Smoking remains one of the major causes of morbidity and mortality worldwide. One approach to assisting smoking cessation is via anti-nicotine vaccines, composed of nicotine-like haptens conjugated to a carrier protein plus adjuvant(s). We have previ
Autor:
Katherine Arch-Douglas, Bruce Thompson, Heather L. Davis, Jennifer Marie Thorn, Dana M. Evans, Michael J. McCluskie, Justin B. Sperry
Publikováno v:
Biologicals : journal of the International Association of Biological Standardization. 44(3)
The United States Food and Drug Administration recently removed the requirement for a General Safety Test (GST) for biologics in the Code of Federal Regulations (21 CFR 610.11). The GST, as well as abnormal toxicity (European Pharmacopeia) and innocu
A protein-based smallpox vaccine protects non-human primates from a lethal monkeypox virus challenge
Autor:
Nicola Richardson-Harman, Yuhong Xiao, Louis J. DeTolla, George W. Buchman, Stuart N. Isaacs, Peter Silvera, Gary H. Cohen, Roselyn J. Eisenberg, Matthew E. Cohen, Heather L. Davis
Publikováno v:
Vaccine. 28:6627-6636
Concerns about infections caused by orthopoxviruses, such as variola and monkeypox viruses, drive ongoing efforts to develop novel smallpox vaccines that are both effective and safe to use in diverse populations. A subunit smallpox vaccine comprising