Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Heather L. Ball"'
Autor:
Marina E Tourlakis, Siyi Zhang, Heather L Ball, Rikesh Gandhi, Hongrui Liu, Jian Zhong, Julie S Yuan, Cynthia J Guidos, Peter R Durie, Johanna M Rommens
Publikováno v:
PLoS Genetics, Vol 11, Iss 6, p e1005288 (2015)
Genetic models of ribosome dysfunction show selective organ failure, highlighting a gap in our understanding of cell-type specific responses to translation insufficiency. Translation defects underlie a growing list of inherited and acquired cancer-pr
Externí odkaz:
https://doaj.org/article/856671ca104e4135a514d8fa8c538e54
Autor:
Bing Zhang, Rikesh Gandhi, Jing Li, J. Jacob Riches, Johanna M. Rommens, Heather L. Ball, Jeremy S. Myers
Publikováno v:
Human Molecular Genetics. 18:3684-3695
Shwachman-Diamond syndrome (SDS; OMIM 260400) results from loss-of-function mutations in the Shwachman-Bodian Diamond syndrome (SBDS) gene. It is a multi-system disorder with clinical features of exocrine pancreatic dysfunction, skeletal abnormalitie
Autor:
Ahmad H. Al-Mestarihi, Melissa V. Turman, Vincenzo Di Marzo, Andrew Vila, Jeffery J. Prusakiewicz, Heather L. Ball, Lawrence J. Marnett
Publikováno v:
Archives of Biochemistry and Biophysics. 464:260-268
The lipoamino acids and endovanilloids have multiple roles in nociception, pain, and inflammation, yet their biological reactivity has not been fully characterized. Cyclooxygenases (COXs) and lipoxygenases (LOs) oxygenate polyunsaturated fatty acids
Autor:
Heather L. Ball, Mark Ehrhardt, David Cortez, Walter J. Chazin, Daniel A. Mordes, Gloria G. Glick
Publikováno v:
Molecular and Cellular Biology. 27:3367-3377
The ATR (ATM and Rad3-related) kinase is essential to maintain genomic integrity. ATR is recruited to DNA lesions in part through its association with ATR-interacting protein (ATRIP), which in turn interacts with the single-stranded DNA binding prote
Autor:
Rikesh Gandhi, Julie S. Yuan, Siyi Zhang, Cynthia J. Guidos, Jian Zhong, Peter R. Durie, Heather L. Ball, Hongrui Liu, Marina E. Tourlakis, Johanna M. Rommens
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 11, Iss 6, p e1005288 (2015)
PLoS Genetics, Vol 11, Iss 6, p e1005288 (2015)
Genetic models of ribosome dysfunction show selective organ failure, highlighting a gap in our understanding of cell-type specific responses to translation insufficiency. Translation defects underlie a growing list of inherited and acquired cancer-pr
Autor:
David Cortez, Heather L. Ball
Publikováno v:
Journal of Biological Chemistry. 280:31390-31396
The ATM and ATR kinases signal cell cycle checkpoint responses to DNA damage. Inactive ATM is an oligomer that is disrupted to form active monomers in response to ionizing radiation. We examined whether ATR is activated by a similar mechanism. We fou
Publikováno v:
Molecular Biology of the Cell. 16:2372-2381
ATR associates with the regulatory protein ATRIP that has been proposed to localize ATR to sites of DNA damage through an interaction with single-stranded DNA (ssDNA) coated with replication protein A (RPA). We tested this hypothesis and found that A
The ATR (ATM and Rad3-Related) kinase is essential to maintain genomic integrity. ATR is recruited to DNA lesions in part through its association with ATR-interacting protein (ATRIP), which in turn interacts with the single-stranded DNA binding prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b14093cce975f346f5b4a7c5f9f83027
https://doi.org/10.21236/ada470345
https://doi.org/10.21236/ada470345