Zobrazeno 1 - 10
of 229
pro vyhledávání: '"Heather L Wilson"'
Autor:
Juan Parra-Aguirre, Roman Nosach, Champika Fernando, Janet E Hill, Heather L Wilson, John C S Harding
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0275173 (2022)
Swine dysentery is causally associated with Brachyspira hampsonii and B. hyodysenteriae infection. Given the importance of transmission models in understanding re-emergent diseases and developing control strategies such as vaccines, the objective of
Externí odkaz:
https://doaj.org/article/cb4cf2d2f47f41fba12b7305360fc125
Publikováno v:
Physiological Reports, Vol 9, Iss 3, Pp n/a-n/a (2021)
Abstract Piglets must acquire passive immunity through colostrum within hours after birth to survive. How colostral macromolecules traverse the small intestinal epithelium may include nonselective pinocytosis and paracellular transport through tight
Externí odkaz:
https://doaj.org/article/7db45d048ace44a681a372877397b0bc
Autor:
Amanda L Miller, J Alex Pasternak, Nicole J Medeiros, Lauren K Nicastro, Sarah A Tursi, Elizabeth G Hansen, Ryan Krochak, Akosiererem S Sokaribo, Keith D MacKenzie, Melissa B Palmer, Dakoda J Herman, Nikole L Watson, Yi Zhang, Heather L Wilson, R Paul Wilson, Aaron P White, Çagla Tükel
Publikováno v:
PLoS Pathogens, Vol 16, Iss 7, p e1008591 (2020)
Reactive arthritis, an autoimmune disorder, occurs following gastrointestinal infection with invasive enteric pathogens, such as Salmonella enterica. Curli, an extracellular, bacterial amyloid with cross beta-sheet structure can trigger inflammatory
Externí odkaz:
https://doaj.org/article/1badb525e2964d4b81ab1e7a66ba92da
Autor:
Karolína Steinerová, John C. S. Harding, Sarah E. Parker, Heather L. Wilson, Arthur Nery Finatto, Yolande M. Seddon
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
Positive emotions can reduce disease susceptibility during infectious challenges in humans, and emerging evidence suggests similar effects in farm animals. Because play behaviour may support a positive emotional state in pigs, this study investigates
Externí odkaz:
https://doaj.org/article/9bf157711d1342ecbb2104c52dc87b05
TFPI1 mediates resistance to doxorubicin in breast cancer cells by inducing a hypoxic-like response.
Autor:
Gerald F Davies, Arnie Berg, Spike D L Postnikoff, Heather L Wilson, Terra G Arnason, Anthony Kusalik, Troy A A Harkness
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84611 (2014)
Thrombin and hypoxia are important players in breast cancer progression. Breast cancers often develop drug resistance, but mechanisms linking thrombin and hypoxia to drug resistance remain unresolved. Our studies using Doxorubicin (DOX) resistant MCF
Externí odkaz:
https://doaj.org/article/4cf44c749f3146f2b0d1421ca3ceb1aa
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51437 (2012)
BACKGROUND: In adult rats, initial exposure to antigens by a mucosal route triggers tolerance such that any subsequent re-exposure, even by a systemic route, results in suppression of immunity. The newborn's gut is semi-permeable for a finite period
Externí odkaz:
https://doaj.org/article/dbbfaca2e28342e992085cc8c47fd434
Autor:
Charlotte E. Moss, Simon A. Johnston, Joshua V. Kimble, Martha Clements, Veryan Codd, Stephen Hamby, Alison H. Goodall, Sumeet Deshmukh, Ian Sudbery, Daniel Coca, Heather L. Wilson, Endre Kiss-Toth
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114073- (2024)
Summary: Macrophages are central innate immune cells whose function declines with age. The molecular mechanisms underlying age-related changes remain poorly understood, particularly in human macrophages. We report a substantial reduction in phagocyto
Externí odkaz:
https://doaj.org/article/4b1acb9fd5b841acafd7c00ff65e1ec6
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Protein misfolding and aggregation play crucial roles in amyloidogenic diseases through the self-assembly of intrinsically disordered proteins (IDPs) in type II diabetes (T2D), Alzheimer's disease (AD) and Parkinson’s disease (PD). PD is t
Externí odkaz:
https://doaj.org/article/af0939432ca448e7b478b2bba39b88f2
Autor:
Mehrab E Hossain, Karina J. Kennedy, Heather L. Wilson, David Spratt, Anson Koehler, Robin B. Gasser, Jan Šlapeta, Carolyn A. Hawkins, Hari Priya Bandi, Sanjaya N. Senanayake
Publikováno v:
Emerging Infectious Diseases, Vol 29, Iss 9, Pp 1900-1903 (2023)
We describe a case in Australia of human neural larva migrans caused by the ascarid Ophidascaris robertsi, for which Australian carpet pythons are definitive hosts. We made the diagnosis after a live nematode was removed from the brain of a 64-year-o
Externí odkaz:
https://doaj.org/article/f18855dd63a941d7a1ec91ac8abe4c72
Autor:
Miguel Hernández-Quiles, Laura Martinez Campesino, Imogen Morris, Zabran Ilyas, Steve Reynolds, Nguan Soon Tan, Paula Sobrevals Alcaraz, Edwin C.A. Stigter, Ákos Varga, János Varga, Robert van Es, Harmjan Vos, Heather L. Wilson, Endre Kiss-Toth, Eric Kalkhoven
Publikováno v:
Molecular Metabolism, Vol 78, Iss , Pp 101829- (2023)
Objective: In vivo studies in humans and mice have implicated the pseudokinase Tribbles 3 (TRIB3) in various aspects of energy metabolism. Whilst cell-based studies indicate a role for TRIB3 in adipocyte differentiation and function, it is unclear if
Externí odkaz:
https://doaj.org/article/f125550a747e4a01a5443dc366d1888f