Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Heather L Fiumera"'
Autor:
Tuc H M Nguyen, Austen Tinz-Burdick, Meghan Lenhardt, Margaret Geertz, Franchesca Ramirez, Mark Schwartz, Michael Toledano, Brooke Bonney, Benjamin Gaebler, Weiwei Liu, John F Wolters, Kenneth Chiu, Anthony C Fiumera, Heather L Fiumera
Publikováno v:
PLoS Genetics, Vol 19, Iss 3, p e1010401 (2023)
Genetic variation in mitochondrial and nuclear genomes can perturb mitonuclear interactions and lead to phenotypic differences between individuals and populations. Despite their importance to most complex traits, it has been difficult to identify the
Externí odkaz:
https://doaj.org/article/a8018cbffb664de689e3a91734a45ce8
Publikováno v:
BMC Evolutionary Biology, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background Mitochondrial function requires numerous genetic interactions between mitochondrial- and nuclear- encoded genes. While selection for optimal mitonuclear interactions should result in coevolution between both genomes, evidence for
Externí odkaz:
https://doaj.org/article/1adde8ebc9a547dfb1d8af2a67e83d26
Autor:
Damien Biot-Pelletier, Stefano Bettinazzi, Isabelle Gagnon-Arsenault, Alexandre K Dubé, Camille Bédard, Tuc H M Nguyen, Heather L Fiumera, Sophie Breton, Christian R Landry
Critical mitochondrial functions, including cellular respiration, rely on frequently interacting components expressed from both the mitochondrial and nuclear genomes. The fitness of eukaryotic organisms depends on a tight collaboration between both g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf9bd48c833bdf87e671b526e81fa7e4
https://doi.org/10.1101/2022.09.11.507487
https://doi.org/10.1101/2022.09.11.507487
Publikováno v:
Mitochondrion. 56:1-14
The multi-lineage differentiation potential is one of the prominent mechanisms through which stem cells can repair damaged tissues. The regenerative potential of stem cells is the manifestation of several changes at the structural and molecular level
Publikováno v:
Mitochondrion. 56
The multi-lineage differentiation potential is one of the prominent mechanisms through which stem cells can repair damaged tissues. The regenerative potential of stem cells is the manifestation of several changes at the structural and molecular level
Publikováno v:
BMC Evolutionary Biology, Vol 20, Iss 1, Pp 1-12 (2020)
BMC Evolutionary Biology
BMC Evolutionary Biology
Background Mitochondrial function requires numerous genetic interactions between mitochondrial- and nuclear- encoded genes. While selection for optimal mitonuclear interactions should result in coevolution between both genomes, evidence for mitonucle
Autor:
Guillaume Charron, Christian R. Landry, Heather L. Fiumera, John F. Wolters, Anthony C. Fiumera, Alec Gaspary
Publikováno v:
Genetics. 209:307-319
Genetic variation in mitochondrial DNA (mtDNA) provides adaptive potential although the underlying genetic architecture of fitness components within mtDNAs is not known. To dissect functional variation within mtDNAs, we first identified naturally occ
Autor:
Christian R. Landry, Mathieu Hénault, Lou Nielly-Thibault, B. Jesse Shapiro, Guillaume Charron, Heather L. Fiumera, Yves Terrat, Jean-Baptiste Leducq
Publikováno v:
Molecular Biology and Evolution
Genome recombination is a major source of genotypic diversity and contributes to adaptation and speciation following interspecies hybridization. The contribution of recombination in these processes has been thought to be largely limited to the nuclea
Autor:
Heather L. Fiumera, Thomas D. Fox, Jessica A. Kelly, Scott A. Saracco, Maitreya J. Dunham, Christine A. Butler
Publikováno v:
Genetics. 182:519-528
Members of the Oxa1/YidC/Alb3 family of protein translocases are essential for assembly of energy-transducing membrane complexes. In Saccharomyces cerevisiae, Oxa1 and its paralog, Cox18, are required for assembly of Cox2, a mitochondrially encoded s
Translocation of Mitochondrially Synthesized Cox2 Domains from the Matrix to the Intermembrane Space
Publikováno v:
Molecular and Cellular Biology. 27:4664-4673
The N-terminal and C-terminal domains of mitochondrially synthesized cytochrome c oxidase subunit II, Cox2, are translocated through the inner membrane to the intermembrane space (IMS). We investigated the distinct mechanisms of N-tail and C-tail exp