Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Heather L Blackburn"'
Publikováno v:
Breast Cancer: Basic and Clinical Research, Vol 11 (2017)
Metastasis is a multistep process that is not well understood. Colonization of a secondary organ requires specific molecular alterations of the host microenvironment. To determine the temporal and spatial changes associated with metastatic disseminat
Externí odkaz:
https://doaj.org/article/de4db9f190f14bedb994784f3b9b0e20
Autor:
Heather L. Blackburn, Seóna McErlean, Gera L. Jellema, Ryan van Laar, Marina N. Vernalis, Darrell L. Ellsworth
Publikováno v:
Genomics Data, Vol 4, Iss C, Pp 50-53 (2015)
Heart disease and related sequelae are a leading cause of death and healthcare expenditure throughout the world. Although many patients opt for surgical interventions, lifestyle modification programs focusing on nutrition and exercise have shown subs
Externí odkaz:
https://doaj.org/article/27808d9fd81b4ec0aa9363b2c1bd0064
Autor:
Heather L. Blackburn, Renata J.M. Engler, Mariam Kashani, Marina N. Vernalis, Darrell L. Ellsworth, N. S. Costantino
Publikováno v:
Obesity Science & Practice. 2:282-292
SummaryObjective Metabolic dysfunction characterized by insulin resistance (IR) is an important risk factor for type-2 diabetes and coronary artery disease (CAD). The aim of this study was to determine if clinical lifestyle interventions differing in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf5f07f7c52937f49804444f3a4bab24
https://doi.org/10.1002/osp4.54
https://doi.org/10.1002/osp4.54
Autor:
Marina N. Vernalis, Kimberly A. Mamula, Renata J.M. Engler, Ryan van Laar, Fionnuala A. McDyer, Darrell L. Ellsworth, Nicholas S. Costantino, Heather L. Blackburn, Gera L. Jellema
Publikováno v:
Obesity. 23:1312-1319
Objective To examine relationships between weight loss through changes in lifestyle and peripheral blood gene expression profiles. Methods A prospective nonrandomized trial was conducted over 1 year in participants undergoing intensive lifestyle modi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2173832b7d10b4c9a4e291a5bcdaffb8
https://doi.org/10.1002/oby.21079
https://doi.org/10.1002/oby.21079
Autor:
Craig D. Shriver, Shahrooz Rabizadeh, Rachel E. Ellsworth, Heather L. Blackburn, Darrell L. Ellsworth, Patrick Soon-Shiong
Publikováno v:
Clinical and Translational Medicine
Clinical and Translational Medicine, Vol 6, Iss 1, Pp 1-19 (2017)
Clinical and Translational Medicine, Vol 6, Iss 1, Pp 1-19 (2017)
Extensive genomic and transcriptomic heterogeneity in human cancer often negatively impacts treatment efficacy and survival, thus posing a significant ongoing challenge for modern treatment regimens. State-of-the-art DNA- and RNA-sequencing methods n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7462e1d7e6b73ada54efbae213078131
http://europepmc.org/articles/PMC5389955
http://europepmc.org/articles/PMC5389955
Autor:
Rachel E. Ellsworth, Heather L. Blackburn, Darrell L. Ellsworth, Patrick Soon-Shiong, Craig D. Shriver
Publikováno v:
Seminars in celldevelopmental biology. 64
The identification of extensive genetic heterogeneity in human breast carcinomas poses a significant challenge for designing effective treatment regimens. Significant genomic evolution often occurs during breast cancer progression, creating variabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76ef4d6eda0737b52afa5d6daf69f550
https://pubmed.ncbi.nlm.nih.gov/27569190
https://pubmed.ncbi.nlm.nih.gov/27569190
Autor:
Darrell L Ellsworth, Nicholas S Costantino, Heather L Blackburn, Renata J Engler, Marina N Vernalis
Publikováno v:
Circulation. 133
Background: Metabolic dysfunction characterized by insulin resistance (IR) is an important risk factor for type-2 diabetes and coronary artery disease (CAD). The Lipoprotein Insulin Resistance (LP-IR) index, derived from measures of lipoprotein subcl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea6ee84651d8983cb32e4fb4ef45f102
https://doi.org/10.1161/circ.133.suppl_1.p108
https://doi.org/10.1161/circ.133.suppl_1.p108
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 27:B77-B77
Background: Although the role of BRCA1 and BRCA2 has been well studied in women of European ancestry, the contribution of these and other genes associated with hereditary cancers remains unknown in other populations. Here, we utilized panel testing t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ec00f3b1c00383070220b84b973e53b
https://doi.org/10.1158/1538-7755.disp17-b77
https://doi.org/10.1158/1538-7755.disp17-b77
Autor:
Marina Vernalis, Heather L. Blackburn, Darrell L. Ellsworth, Renata Engler, Kimberly A. Mamula
Publikováno v:
Journal of the American College of Cardiology. 65(10)
Metabolic dysfunction characterized by insulin resistance (IR) is an important risk factor for developing type 2 diabetes and coronary artery disease (CAD). The Lipoprotein Insulin Resistance (LP-IR) score, derived from measures of lipoprotein subcla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15637f65c0fc5baffc51beafaacccf38
Autor:
Heather L. Blackburn, Rachel E. Ellsworth, Craig D. Shriver, Bradley Schroeder, Darrell L. Ellsworth, Clesson Turner
Publikováno v:
Current Genomics
Next-generation sequencing (NGS) technologies allow for the generation of whole exome or whole genome sequencing data, which can be used to identify novel genetic alterations associated with defined phenotypes or to expedite discovery of functional v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51b2292cbfb01d27a4a6e7b64ba22239
https://pubmed.ncbi.nlm.nih.gov/26069456
https://pubmed.ncbi.nlm.nih.gov/26069456