Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Heather Kroona"'
Autor:
Lyle W. Spruce, Douglas L. Garnert, Heather Kroona, John C. Cheronis, Sherman E. Ross, Gregory Von Burg, Albert Gyorkos, Carmen E. Burgos-Lepley, Larry D. Bratton, Tyler S. Drennan, Anna Ettinger, Maciej Wieczorek, Carolyn G. Pilkington
Publikováno v:
Archives of Biochemistry and Biophysics. 367:193-201
A series of α-ketooxadiazole compounds was prepared and evaluated in vitro as potential inhibitors of human neutrophil elastase (HNE), proteinase-3 (PR-3), and porcine pancreatic elastase (PPE). Several compounds have been found to be very potent, f
Autor:
Claire Coeshott, Sherman E. Ross, Christie Ohnemus, Anna Pilyavskaya, John C. Cheronis, Axel H. Leimer, Heather Kroona, Maciej Wieczorek
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 96(11)
Two important cytokines mediating inflammation are tumor necrosis factor alpha (TNFalpha) and IL-1beta, both of which require conversion to soluble forms by converting enzymes. The importance of TNFalpha-converting enzyme and IL-1beta-converting enzy