Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Heather K. Hughes"'
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-15 (2022)
Abstract Background Inflammation and increases in inflammatory cytokines are common findings in psychiatric disorders such as schizophrenia (SCZ), bipolar disorder (BD), and major depressive disorder (MDD). Meta-analyses of studies that measured circ
Externí odkaz:
https://doaj.org/article/5924c56233c4487bb1ff1df4190dc226
Autor:
Heather K. Hughes, Megan E. Rowland, Charity E. Onore, Sally Rogers, Annie Vogel Ciernia, Paul Ashwood
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Autism spectrum disorder (ASD) is a complex developmental disorder characterized by deficits in social interactions, communication, and stereotypical behaviors. Immune dysfunction is a common co-morbidity seen in ASD, with innate immune acti
Externí odkaz:
https://doaj.org/article/bca724e7c76c463890ac53741981a4cc
Differential Macrophage Responses in Affective Versus Non-Affective First-Episode Psychosis Patients
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Increased innate immune activation and inflammation are common findings in psychotic and affective (mood) disorders such as schizophrenia (SCZ), bipolar disorder (BD), and major depressive disorder (MDD), including increased numbers and activation of
Externí odkaz:
https://doaj.org/article/b3e0b3da6fd94e68a609b2f89c05ec65
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 1042 (2022)
This study investigated the effect of antibiotics administered to pregnant dams on offspring gut microbiome composition and metabolic capabilities, and how these changes in the microbiota may influence their immune responses in both the periphery and
Externí odkaz:
https://doaj.org/article/81743ca5dc4f43aa986ee33017304a14
Publikováno v:
Brain Sciences, Vol 12, Iss 2, p 220 (2022)
The prevalence of autism spectrum disorder (ASD) has starkly increased, instigating research into risk factors for ASD. This research has identified immune risk factors for ASD, along with evidence of immune dysfunction and excess inflammation freque
Externí odkaz:
https://doaj.org/article/1a44f3d4720c4342a536ed199f46cfab
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Autism spectrum disorders (ASD) are a group of heterogeneous neurological disorders that are highly variable and are clinically characterized by deficits in social interactions, communication, and stereotypical behaviors. Prevalence has risen from 1
Externí odkaz:
https://doaj.org/article/619a64555a2741069f8cdfa833224600
Autor:
Heather K. Hughes, Paul Ashwood
Publikováno v:
Frontiers in Psychiatry, Vol 9 (2018)
The gut microbiota are known to have a profound influence on both mucosal and systemic immunity and are important for gastrointestinal (GI) function. In addition, new evidence shows that the microbiota significantly influence neurodevelopment and beh
Externí odkaz:
https://doaj.org/article/cfbced03485949389102e36e0739e4a1
Publikováno v:
International journal of molecular sciences, vol 23, iss 21
International Journal of Molecular Sciences; Volume 23; Issue 21; Pages: 12879
International Journal of Molecular Sciences; Volume 23; Issue 21; Pages: 12879
This study aimed to investigate the immediate and continual perturbation to the gut microbiota of offspring in the weeks post-weaning and how these may be modulated by treating pregnant C57BL/6J dams with antibiotics (ABX). We used a broad-spectrum a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c9b62214a4b53e93d4555646b74041
https://escholarship.org/uc/item/7097t5n2
https://escholarship.org/uc/item/7097t5n2
Autor:
Heather K. Hughes, P. Ashwood
Publikováno v:
Brain Behav Immun Health
Brain, Behavior, & Immunity-Health, Vol 2, Iss, Pp 100038-(2020)
Brain, Behavior, & Immunity-Health, Vol 2, Iss, Pp 100038-(2020)
Disturbances of the immune system and immune responses after activation are a common finding in neuropsychiatric disorders. Psychotic and affective disorders such as major depressive disorder (MDD), schizophrenia (SCZ) and bipolar disorder (BD) also
Publikováno v:
Current neurology and neuroscience reports, vol 18, iss 11
PURPOSE OF REVIEW: There is a growing body of evidence indicating the gut microbiota influence neurodevelopment and behavior. The purposes of this review are to provide an overview of studies analyzing the microbiota and their metabolites in autism s