EphrinA1-Fc Attenuates Ventricular Remodeling and Dysfunction in Chronically Nonreperfused WT but not EphA2-R-M mice

Autor: Uma M Sharma, R Christopher Chase, Jitka A. I. Virag, Susan D. Kent, Victoria A Chan, Maliha Bhuiyan, Smrithi Valsaraj, K'Shylah S Whitehurst, Heather K Estes

Publikováno v: International Journal of Molecular Sciences
Volume 21
Issue 16
International Journal of Molecular Sciences, Vol 21, Iss 5811, p 5811 (2020)

Background: EphrinA1-Fc abolishes acute I/R injury and attenuates nonreperfused cardiac injury 4 days after permanent occlusion in mice. The goal of this study was to assess the capacity of a single intramyocardial administration of ephrinA1-Fc at th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edc3065f42b098b9a0136cc7a6ee6b16
https://pubmed.ncbi.nlm.nih.gov/32823610

EphrinA1-Fc attenuates myocardial ischemia/reperfusion injury in mice

Autor: Jitka A. I. Virag, Uma M Sharma, David W Wert, Augustin DuSablon, Robert C Chase, Eleftherios Vlahos, K'Shylah S Whitehurst, Justin Parks, Heather K Estes

Publikováno v: PLoS ONE
PLoS ONE, Vol 12, Iss 12, p e0189307 (2017)

EphrinA1, a membrane-bound receptor tyrosine kinase ligand expressed in healthy cardiomyocytes, is lost in injured cells following myocardial infarction. Previously, we have reported that a single intramyocardial injection of chimeric ephrinA1-Fc at

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c54cacc306852ee02054da89098509e9
https://doi.org/10.1371/journal.pone.0189307