Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Heather J. Ray"'
Autor:
Chenbei Chang, Heather J. Ray
Publikováno v:
Dev Biol
The transcription factor Hypermethylated in Cancer 1 (HIC1) is associated with both tumorigenesis and the complex human developmental disorder Miller-Dieker Syndrome. While many studies have characterized HIC1 as a tumor suppressor, HIC1 function in
Autor:
Aimee L Signarovitz, Heather J Ray, Jieh-Juen Yu, M N Guentzel, James P Chambers, Karl E Klose, Bernard P Arulanandam
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47639 (2012)
The need for an efficacious vaccine against Francisella tularensis is a consequence of its low infectious dose and high mortality rate if left untreated. This study sought to characterize a live attenuated subspecies novicida-based vaccine strain (U1
Externí odkaz:
https://doaj.org/article/161ed19966b34d90b2919b7e19437478
Autor:
Heather J Ray, Ping Chu, Terry H Wu, C Rick Lyons, Ashlesh K Murthy, M Neal Guentzel, Karl E Klose, Bernard P Arulanandam
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e9952 (2010)
The pathogenesis of Francisella tularensis, the causative agent of tularemia, has been primarily characterized in mice. However, the high degree of sensitivity of mice to bacterial challenge, especially with the human virulent strains of F. tularensi
Externí odkaz:
https://doaj.org/article/e8e3aa69be004e0fa4caa812a79ed972
Publikováno v:
Development (Cambridge, England). 145(24)
Apical constriction regulates epithelial morphogenesis during embryonic development, but how this process is controlled is not understood completely. Here, we identify a Rho guanine nucleotide exchange factor (GEF) gene plekhg5 as an essential regula
Publikováno v:
Wiley Interdisciplinary Reviews: Developmental Biology. 3:59-68
The neural tube (NT), the embryonic precursor of the vertebrate brain and spinal cord, is generated by a complex and highly dynamic morphological process. In mammals, the initially flat neural plate bends and lifts bilaterally to generate the neural
Autor:
Heather J. Ray, Lee Niswander
Publikováno v:
Developmental biology. 416(2)
The embryonic brain and spinal cord initially form through the process of neural tube closure (NTC). NTC is thought to be highly similar between rodents and humans, and studies of mouse genetic mutants have greatly increased our understanding of the
Autor:
Lee Niswander, Heather J. Ray
Publikováno v:
Development. 139:1701-1711
Tissue fusion events during embryonic development are crucial for the correct formation and function of many organs and tissues, including the heart, neural tube, eyes, face and body wall. During tissue fusion, two opposing tissue components approach
Autor:
Lee Niswander, Heather J. Ray
Publikováno v:
Development.
The transcription factor Grainyhead-like 2 (GRHL2) is expressed in non-neural ectoderm (NNE) and Grhl2 loss results in fully penetrant cranial neural tube defects (NTDs) in mice. GRHL2 activates expression of several epithelial genes, however additio
Publikováno v:
Wiley interdisciplinary reviews. Developmental biology. 3(1)
The neural tube (NT), the embryonic precursor of the vertebrate brain and spinal cord, is generated by a complex and highly dynamic morphological process. In mammals, the initially flat neural plate bends and lifts bilaterally to generate the neural
Autor:
Lee Niswander, Heather J. Ray
Publikováno v:
Journal of Cell Science. 129:e1.2-e1.2
The transcription factor grainyhead-like 2 (GRHL2) is expressed in non-neural ectoderm (NNE) and Grhl2 loss results in fully penetrant cranial neural tube defects (NTDs) in mice. GRHL2 activates expression of several epithelial genes; however, additi