Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Heather J. McCrea"'
Autor:
Tae-Eun Park, Nur Mustafaoglu, Anna Herland, Ryan Hasselkus, Robert Mannix, Edward A. FitzGerald, Rachelle Prantil-Baun, Alexander Watters, Olivier Henry, Maximilian Benz, Henry Sanchez, Heather J. McCrea, Liliana Christova Goumnerova, Hannah W. Song, Sean P. Palecek, Eric Shusta, Donald E. Ingber
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
In vitro blood-brain barrier (BBB) models do not fully recapitulate the in vivo barrier function. Here the authors develop an organ-on-a-chip BBB model using iPS-derived human brain endothelial cells differentiated under hypoxia, primary human pericy
Externí odkaz:
https://doaj.org/article/83253cf0aed94f3c93f14d16e82efff7
Autor:
Gareth P. Gilna, Jamie E. Clarke, Michael Silva, Rebecca A. Saberi, Joshua P. Parreco, Chad M. Thorson, Heather J. McCrea
Publikováno v:
Child's Nervous System. 39:1021-1027
Autor:
Fan Yang, Jezabel Rodriguez-Blanco, Jun Long, Marzena Swiderska-Syn, Daniel T. Wynn, Bin Li, Chen Shen, Anmada Nayak, Yuguang Ban, Xiaodian Sun, Robert K. Suter, Heather J. McCrea, Anthony J. Capobianco, Nagi G. Ayad, David J. Robbins
Publikováno v:
Mol Cancer Res
Dysregulation of Sonic hedgehog (SHH) signaling drives the growth of distinct cancer subtypes, including medulloblastoma (MB). Such cancers have been treated in the clinic with a number of clinically relevant SHH inhibitors, the majority of which tar
Autor:
David J. Robbins, Nagi G. Ayad, Anthony J. Capobianco, Heather J. McCrea, Robert K. Suter, Xiaodian Sun, Yuguang Ban, Anmada Nayak, Chen Shen, Bin Li, Daniel T. Wynn, Marzena Swiderska-Syn, Jun Long, Jezabel Rodriguez-Blanco, Fan Yang
Supplementary Figure from A Druggable UHRF1/DNMT1/GLI Complex Regulates Sonic Hedgehog–Dependent Tumor Growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10389b39f7c2504b80af45872eabbf86
https://doi.org/10.1158/1541-7786.22527851.v1
https://doi.org/10.1158/1541-7786.22527851.v1
Autor:
David J. Robbins, Anthony J. Capobianco, William A. Weiss, Martine F. Roussel, Heather J. McCrea, Nagi G. Ayad, Noriyuki Kasahara, Sara Collins, Darren Orton, Fan Yang, Chen Shen, Jun Long, Bin Li, Jezabel Rodriguez-Blanco
Supplemental Figures 1-5 with corresponding legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ee9992a96d5f38c1a0194a602dade4
https://doi.org/10.1158/1078-0432.22467444.v1
https://doi.org/10.1158/1078-0432.22467444.v1
Autor:
David J. Robbins, Anthony J. Capobianco, William A. Weiss, Martine F. Roussel, Heather J. McCrea, Nagi G. Ayad, Noriyuki Kasahara, Sara Collins, Darren Orton, Fan Yang, Chen Shen, Jun Long, Bin Li, Jezabel Rodriguez-Blanco
Purpose: Although most children with medulloblastoma are cured of their disease, Sonic Hedgehog (SHH) subgroup medulloblastoma driven by TRP53 mutations is essentially lethal. Casein kinase 1α (CK1α) phosphorylates and destabilizes GLI transcriptio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e25c3ebce29f7768642611924dd70353
https://doi.org/10.1158/1078-0432.c.6526641
https://doi.org/10.1158/1078-0432.c.6526641
Autor:
Victor M. Lu, Evan Kreuger, Joacir G. Cordeiro, Toba N. Niazi, Jonathan R. Jagid, Heather J. McCrea
Publikováno v:
Child's Nervous System. 38:1735-1742
Autor:
Michael A Silva, Henry Chang, Heather J. McCrea, Corinna G. Levine, Erin K. Reilly, John Weng
Publikováno v:
Child's Nervous System. 38:1035-1039
Mucoceles in the sphenoid sinus are rare, making up 1–3% of all paranasal sinus mucoceles. Sphenoid sinus mucoceles among pediatric patients are uncommon and have a range of presentations due to their proximity to other structures, in rare cases ca
Autor:
Victor M. Lu, Victoria A. Pinilla Escobar, Rebecca A. Saberi, Gareth P. Gilna, Joshua D. Burks, Toba N. Niazi, Chad M. Thorson, Heather J. McCrea
Publikováno v:
Journal of neurosurgery. Pediatrics. 31(1)
OBJECTIVE Civilian gunshot wounds (GSWs) involving the skeletal spine and spinal cord in pediatric patients are fortunately rare. Nevertheless, their presentation mandates judicious evaluation, and their clinical outcomes remain poorly defined. Thus,
Autor:
Marzena, Swiderska-Syn, Júlia, Mir-Pedrol, Alexander, Oles, Olga, Schleuger, April D, Salvador, Sean M, Greiner, Cara, Seward, Fan, Yang, Benjamin R, Babcock, Chen, Shen, Daniel T, Wynn, Avencia, Sanchez-Mejias, Timothy R, Gershon, Vanesa, Martin, Heather J, McCrea, Kathryn G, Lindsey, Carsten, Krieg, Jezabel, Rodriguez-Blanco
Publikováno v:
Science advances. 8(29)
SRY (sex determining region Y)-box 2 (SOX2)-labeled cells play key roles in chemoresistance and tumor relapse; thus, it is critical to elucidate the mechanisms propagating them. Single-cell transcriptomic analyses of the most common malignant pediatr