Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Heather J. Kolpa"'
Publikováno v:
Mammalian genome : official journal of the International Mammalian Genome Society. 33(2)
Here we provide a brief review of relevant background before presenting results of our investigation into the interplay between scaffold attachment factor A (SAF-A), chromatin-associated RNAs, and DNA condensation. SAF-A, also termed heterogenous nuc
Publikováno v:
Mol Cell
Nuclear chromosomes transcribe far more RNA than required to encode protein. Here we investigate whether non-coding RNA broadly contributes to cytological-scale chromosome territory architecture. We develop a procedure that depletes soluble proteins,
Autor:
Russell A. Norris, Heather J. Kolpa, David S. Peal, Roger R. Markwald, Andrea C. Giokas, Calum A. MacRae, Joyce Bischoff, David J. Milan, Patrick T. Ellinor, Shibnath Ghatak, Stacey N. Lynch, Suniti Misra
Publikováno v:
Development. 140:2172-2180
The discovery of small non-coding microRNAs has revealed novel mechanisms of post-translational regulation of gene expression, the implications of which are still incompletely understood. We focused on microRNA 21 (miR-21), which is expressed in card
Publikováno v:
Dev Cell
In mammalian female cells, human/mouse XIST/Xist RNA accumulates and stably localizes to the inactive X chromosome territory in cis (Clemson et al., 1996). A recent study examined how this RNA is anchored to the X chromosome. Hasegawa et al. (2010) r
Autor:
Heather J. Kolpa, Alvin Gomez, Lisa L. Hall, Dawn M. Carone, Frank O. Fackelmayer, Jeanne B. Lawrence, Meg Byron, Nitish Mehta
Publikováno v:
Cell. 156(5)
Summary Recent studies recognize a vast diversity of noncoding RNAs with largely unknown functions, but few have examined interspersed repeat sequences, which constitute almost half our genome. RNA hybridization in situ using C 0 T-1 (highly repeated