Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Heather J. Finlay"'
Synthesis of novel [3,2-b]indole fused oleanolic acids as potential inhibitors of cell proliferation
Publikováno v:
ARKIVOC, Vol 2002, Iss 12, Pp 38-46 (2003)
Externí odkaz:
https://doaj.org/article/d15d833ca25d4d0e8dc83243673c83c3
Autor:
Jeremy M. Richter, J. Alex Bates, Peter Gargalovic, Joelle M. Onorato, Claudia Generaux, Tao Wang, David A. Gordon, Ruth R. Wexler, Heather J. Finlay
Publikováno v:
Bioorganicmedicinal chemistry letters. 73
Agonism of the apelin receptor (APJ) has demonstrated beneficial effects in models of heart failure. We have previously disclosed compounds such as 4, which showed good APJ agonist activity but were metabolized to the mono-demethylated, non-interconv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::898309a657734b060ea109a87904cf66
https://pubmed.ncbi.nlm.nih.gov/35817293
https://pubmed.ncbi.nlm.nih.gov/35817293
Autor:
Joelle M, Onorato, Carrie, Xu, Xue-Qing, Chen, Anne V, Rose, Claudia, Generaux, Kimberley, Lentz, Petia, Shipkova, Susan, Arthur, James K, Hennan, Roy, Haskell, Michael C, Myers, R Michael, Lawrence, Heather J, Finlay, Michael, Basso, Jeffrey, Bostwick, Gayani, Fernando, Ricardo, Garcia, Samuel, Hellings, Mei-Yin, Hsu, Rongan, Zhang, Lei, Zhao, Peter, Gargalovic
Publikováno v:
Analytical biochemistry. 568
Apelin, the endogenous ligand for the APJ receptor, has generated interest due to its beneficial effects on the cardiovascular system. Synthesized as a 77 amino acid preproprotein, apelin is post-translationally cleaved to a series of shorter peptide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::31163504c7997bce33851b532d5f50ee
https://pubmed.ncbi.nlm.nih.gov/30605634
https://pubmed.ncbi.nlm.nih.gov/30605634
Autor:
Prashantha, Gunaga, John, Lloyd, Somanadham, Mummadi, Abhisek, Banerjee, Naveen Kumar, Dhondi, James, Hennan, Veena, Subray, Ramya, Jayaram, Nagendra, Rajugowda, Kommuri, Umamaheshwar Reddy, Duraimurugan, Kumaraguru, Umasankar, Mandal, Dasthagiri, Beldona, Ashok Kumar, Adisechen, Navnath, Yadav, Jayakumar, Warrier, James A, Johnson, Harinath, Sale, Siva Prasad, Putlur, Ajay, Saxena, Anjaneya, Chimalakonda, Sandhya, Mandlekar, MaryLee, Conder, Dezhi, Xing, Arun Kumar, Gupta, Anuradha, Gupta, Richard, Rampulla, Arvind, Mathur, Paul, Levesque, Ruth R, Wexler, Heather J, Finlay
Publikováno v:
Journal of medicinal chemistry. 60(9)
We have recently disclosed 5-phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)quinazolin-4-amine 1 as a potent I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c2f58bc0896c8f18234c0aaf3b7d84e6
https://pubmed.ncbi.nlm.nih.gov/28418664
https://pubmed.ncbi.nlm.nih.gov/28418664
Autor:
George M. Strunz, Heather J. Finlay
Publikováno v:
Canadian Journal of Chemistry. 74:419-432
The Sakai aryl aldehyde – cyclic ketone aldol – Grob fragmentation sequence was extended to cinnamaldehyde and cyclohexanone, and the product was elaborated to analogues of the alkaloid piperstachine. The effects of substituents on the reaction i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a0f124e0dd80f7efb740a8784f07522
https://doi.org/10.1139/v96-046
https://doi.org/10.1139/v96-046
Autor:
Heather J. Finlay, George M. Strunz
Publikováno v:
Tetrahedron. 50:11113-11122
Pipercide and piperolein A, unsaturated amides from Piper nigrum, were prepared in overall yields of 21% and 35% respectively, by a new, short and efficient strategy, in which the key step was the aldol-Grob-type fragmentation sequence recently repor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43b905903c3e5a77366e9d51ece8a888
https://doi.org/10.1016/s0040-4020(01)89414-x
https://doi.org/10.1016/s0040-4020(01)89414-x
Autor:
Heather J. Finlay, George M. Strunz
Publikováno v:
ChemInform. 26
Pipercide and piperolein A, unsaturated amides from Piper nigrum, were prepared in overall yields of 21% and 35% respectively, by a new, short and efficient strategy, in which the key step was the aldol-Grob-type fragmentation sequence recently repor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3edfddc4f3f32c05c6614d673417930d
https://doi.org/10.1002/chin.199509202
https://doi.org/10.1002/chin.199509202
Autor:
George M. Strunz, Heather J. Finlay
Publikováno v:
Phytochemistry. 39:731-733
Sarmentosine, 7-(3′,4′-methylenedioxyphenyl)-2E,6E-heptadienoic acid pyrrolidylamide, isolated from fruit of Piper sarmentosum, was synthesized in an overall yield of 21%, by a short efficient pathway in which the key step was an aldol-Grob fragm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e92b8bc1d007cc950c422d050ecf7ca
https://doi.org/10.1016/0031-9422(95)00077-k
https://doi.org/10.1016/0031-9422(95)00077-k
Autor:
Heather J. Finlay, John Lloyd, Wayne Vaccaro, Alexander Kover, Lin Yan, Gauri Bhave, Joseph Prol, Tram Huynh, Rao Bhandaru, Yolanda Caringal, John DiMarco, Jinping Gan, Tim Harper, Christine Huang, Mary Lee Conder, Huabin Sun, Paul Levesque, Michael Blanar, Karnail Atwal, Ruth Wexler
Publikováno v:
Journal of Medicinal Chemistry. 56:7133-7133
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34e502f4948210914df68a9cbb04ee89
https://doi.org/10.1021/jm4010576
https://doi.org/10.1021/jm4010576