Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Heather J. Ezelle"'
Autor:
Krishnamurthy Malathi, Mohammad Adnan Siddiqui, Shubham Dayal, Merna Naji, Heather J. Ezelle, Chun Zeng, Aimin Zhou, Bret A. Hassel
Publikováno v:
mBio, Vol 5, Iss 6 (2014)
ABSTRACT The actin cytoskeleton and its network of associated proteins constitute a physical barrier that viruses must circumvent to gain entry into cells for productive infection. The mechanisms by which the physical signals of infection are sensed
Externí odkaz:
https://doaj.org/article/83b76e73f0084d90a5f089dc2009b7cb
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 1, p 74 (2016)
The interferon (IFN)-regulated endoribonuclease RNase-L is involved in multiple aspects of the antimicrobial innate immune response. It is the terminal component of an RNA cleavage pathway in which dsRNA induces the production of RNase-L-activating 2
Externí odkaz:
https://doaj.org/article/376fc65c88ef45bea1c65947df558f24
Autor:
Lauren Schnaper, Heather J Ezelle, Kevin J. Cullen, Bret A Hassel, Theresa M. Geiman, Rena S Lapidus
Publikováno v:
J Cancer Educ
The demand for biomedical researchers and health science professionals has increased over the past several decades. This need is particularly acute in the fields of cancer research and oncology in which technological advances have fueled an unprecede
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caec1f65c5d98e8237d51718a228264b
https://europepmc.org/articles/PMC7384627/
https://europepmc.org/articles/PMC7384627/
RNase-L Control of Cellular mRNAs: Roles in Biologic Functions and Mechanisms of Substrate Targeting
Publikováno v:
Journal of Interferon & Cytokine Research. 34:275-288
RNase-L is a mediator of type 1 interferon-induced antiviral activity that has diverse and critical cellular roles, including the regulation of cell proliferation, differentiation, senescence and apoptosis, tumorigenesis, and the control of the innat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8abcaee6fd52f70e0b841131e731409
https://doi.org/10.1089/jir.2013.0147
https://doi.org/10.1089/jir.2013.0147
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 17, Iss 1, p 74 (2016)
International Journal of Molecular Sciences, Vol 17, Iss 1, p 74 (2016)
The interferon (IFN)-regulated endoribonuclease RNase-L is involved in multiple aspects of the antimicrobial innate immune response. It is the terminal component of an RNA cleavage pathway in which dsRNA induces the production of RNase-L-activating 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3e531ab5e6dde314db65864668140f4
Publikováno v:
Wiley Interdisciplinary Reviews: RNA. 2:58-78
In mammals the type 1 interferon (IFN) system functions as the primary innate antiviral defense and more broadly as a stress response and regulator of diverse homeostatic mechanisms. RNA plays a central role in the induction of IFN and in its biologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4e9d25e35f9ad6524e0d2294277272f
https://doi.org/10.1002/wrna.32
https://doi.org/10.1002/wrna.32
Autor:
Jeffrey D. Hasday, Xiaoling Li, Stefanie N. Vogel, Saroj Kant Mohapatra, Alan S. Cross, Heather J. Ezelle, Janette M. Harro, Bret A. Hassel, Oswald Crasta, Kari Ann Shirey, Lei Zhang, Tae Jin Kang
Publikováno v:
Proceedings of the National Academy of Sciences. 105:20816-20821
Type I IFNs were discovered as the primary antiviral cytokines and are now known to serve critical functions in host defense against bacterial pathogens. Accordingly, established mediators of IFN antiviral activity may mediate previously unrecognized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::811d0a25b6565af5e84f63ad51d35f71
https://doi.org/10.1073/pnas.0807265105
https://doi.org/10.1073/pnas.0807265105
Publikováno v:
Virology. 373(1):85-97
The activation of IRF-3 during the early stages of viral infection is critical for the initiation of the antiviral response; however the activation of IRF-3 in HIV-1 infected cells has not yet been characterized. We demonstrate that the early steps o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b89a17affc4826b39e032e442a511911
Publikováno v:
Journal of Virology. 80:6993-7008
We have generated replication-competent (VSV-C/E1/E2) and nonpropagating (VSVΔG-C/E1/E2) vesicular stomatitis virus (VSV) contiguously expressing the structural proteins of hepatitis C virus (HCV; core [C] and glycoproteins E1 and E2) and report on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc674ae83aaa3b4925aca99484e1eeea
https://doi.org/10.1128/jvi.00365-06
https://doi.org/10.1128/jvi.00365-06
Autor:
Chun Zeng, Bret A. Hassel, Krishnamurthy Malathi, Merna Naji, Heather J. Ezelle, Aimin Zhou, Mohammad Adnan Siddiqui, Shubham Dayal
Publikováno v:
mBio
mBio, Vol 5, Iss 6 (2014)
mBio, Vol 5, Iss 6 (2014)
The actin cytoskeleton and its network of associated proteins constitute a physical barrier that viruses must circumvent to gain entry into cells for productive infection. The mechanisms by which the physical signals of infection are sensed by the ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a0cd1831926b8547a44c1bd9c8328c5
https://doi.org/10.1128/mbio.02012-14
https://doi.org/10.1128/mbio.02012-14