Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Heather J, McKinnon"'
Autor:
Owen J. Sansom, Martin Bushell, Anne E. Willis, Joanne Edwards, John Le Quesne, William J. Faller, Heather J. McKinnon, Martin E. Swarbrick, Neil P. Jones, Christopher G. Proud, Nahum Sonenberg, Kevin M. Haigis, Nicola Valeri, Georgios Vlachogiannis, Andrew D. Campbell, Joseph A. Waldron, Rene Jackstadt, Joshua D. Leach, Emma Stanway, Kerri McArthur, Anne Cheasty, Craig MacKay, Laura McDonald, Rachael C.L. Smith, Dustin J. Flanagan, Rachel A. Ridgway, Kathryn Gilroy, Arafath K. Najumudeen, Ewan M. Smith, Sebastian May-Wilson, David M. Gay, Georgios Kanellos, Ana Teodosio, Leah Officer, Kathryn Pennel, Nikola Vlahov, George L. Skalka, Constantinos Alexandrou, John R.P. Knight
All supplemental figures and legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cee3a26e547749f005f869f86f6004e
https://doi.org/10.1158/2159-8290.22540555
https://doi.org/10.1158/2159-8290.22540555
Autor:
Owen J. Sansom, Martin Bushell, Anne E. Willis, Joanne Edwards, John Le Quesne, William J. Faller, Heather J. McKinnon, Martin E. Swarbrick, Neil P. Jones, Christopher G. Proud, Nahum Sonenberg, Kevin M. Haigis, Nicola Valeri, Georgios Vlachogiannis, Andrew D. Campbell, Joseph A. Waldron, Rene Jackstadt, Joshua D. Leach, Emma Stanway, Kerri McArthur, Anne Cheasty, Craig MacKay, Laura McDonald, Rachael C.L. Smith, Dustin J. Flanagan, Rachel A. Ridgway, Kathryn Gilroy, Arafath K. Najumudeen, Ewan M. Smith, Sebastian May-Wilson, David M. Gay, Georgios Kanellos, Ana Teodosio, Leah Officer, Kathryn Pennel, Nikola Vlahov, George L. Skalka, Constantinos Alexandrou, John R.P. Knight
KRAS-mutant colorectal cancers are resistant to therapeutics, presenting a significant problem for ∼40% of cases. Rapalogs, which inhibit mTORC1 and thus protein synthesis, are significantly less potent in KRAS-mutant colorectal cancer. Using Kras-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f56670615fce027f717d8d9f47081b8
https://doi.org/10.1158/2159-8290.c.6549409
https://doi.org/10.1158/2159-8290.c.6549409
Autor:
Anthony J. Chalmers, Michael F. Olson, Martin Drysdale, Heather J. McKinnon, Justin Bower, William M. Holmes, Mairi Sime, Patricia McConnell, Alexander W. Schüttelkopf, Duncan McArthur, Mokdad Mezna, Jennifer Konczal, Christopher H. Gray, Kathryn Gill, Diane Crighton, Daniel R. Croft, Abdulrahman Hussain Qaisi, Richa Vasan, Ariadni Kouzeli, Laura McDonald, Antoine Vallatos, Lesley Gilmour, Karen Strathdee, Joanna L. Birch
Increased GBM cell invasion in vivo is confirmed by a human specific antibody against HLA and measurement of tumour volume by multi-slice T2 MR imaging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91c812a3fdd214f4e6d8a56b4dd30440
https://doi.org/10.1158/0008-5472.22419329.v1
https://doi.org/10.1158/0008-5472.22419329.v1
Autor:
Anthony J. Chalmers, Michael F. Olson, Martin Drysdale, Heather J. McKinnon, Justin Bower, William M. Holmes, Mairi Sime, Patricia McConnell, Alexander W. Schüttelkopf, Duncan McArthur, Mokdad Mezna, Jennifer Konczal, Christopher H. Gray, Kathryn Gill, Diane Crighton, Daniel R. Croft, Abdulrahman Hussain Qaisi, Richa Vasan, Ariadni Kouzeli, Laura McDonald, Antoine Vallatos, Lesley Gilmour, Karen Strathdee, Joanna L. Birch
GFP E2 cells irradiated with 2Gy in an ex vivo brain slice motility assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84dede0e8dcead141e4ddf3499fcc106
https://doi.org/10.1158/0008-5472.22419311.v1
https://doi.org/10.1158/0008-5472.22419311.v1
Autor:
Anthony J. Chalmers, Michael F. Olson, Martin Drysdale, Heather J. McKinnon, Justin Bower, William M. Holmes, Mairi Sime, Patricia McConnell, Alexander W. Schüttelkopf, Duncan McArthur, Mokdad Mezna, Jennifer Konczal, Christopher H. Gray, Kathryn Gill, Diane Crighton, Daniel R. Croft, Abdulrahman Hussain Qaisi, Richa Vasan, Ariadni Kouzeli, Laura McDonald, Antoine Vallatos, Lesley Gilmour, Karen Strathdee, Joanna L. Birch
Glioblastoma (GBM) is an aggressive and incurable primary brain tumor that causes severe neurologic, cognitive, and psychologic symptoms. Symptoms are caused and exacerbated by the infiltrative properties of GBM cells, which enable them to pervade th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac401113ed7e60c5f57c073638f87832
https://doi.org/10.1158/0008-5472.c.6510344.v1
https://doi.org/10.1158/0008-5472.c.6510344.v1
Autor:
Anthony J. Chalmers, Michael F. Olson, Martin Drysdale, Heather J. McKinnon, Justin Bower, William M. Holmes, Mairi Sime, Patricia McConnell, Alexander W. Schüttelkopf, Duncan McArthur, Mokdad Mezna, Jennifer Konczal, Christopher H. Gray, Kathryn Gill, Diane Crighton, Daniel R. Croft, Abdulrahman Hussain Qaisi, Richa Vasan, Ariadni Kouzeli, Laura McDonald, Antoine Vallatos, Lesley Gilmour, Karen Strathdee, Joanna L. Birch
Subconfluent migration assays in the presence of 100nM BDP-9066
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::687d8b58ae80e589bf92951c7e4a8178
https://doi.org/10.1158/0008-5472.22419302
https://doi.org/10.1158/0008-5472.22419302
Autor:
Anthony J. Chalmers, Michael F. Olson, Martin Drysdale, Heather J. McKinnon, Justin Bower, William M. Holmes, Mairi Sime, Patricia McConnell, Alexander W. Schüttelkopf, Duncan McArthur, Mokdad Mezna, Jennifer Konczal, Christopher H. Gray, Kathryn Gill, Diane Crighton, Daniel R. Croft, Abdulrahman Hussain Qaisi, Richa Vasan, Ariadni Kouzeli, Laura McDonald, Antoine Vallatos, Lesley Gilmour, Karen Strathdee, Joanna L. Birch
Summary of the properties of BDP-9066
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1410083252efd93e9831d1538176457b
https://doi.org/10.1158/0008-5472.22419317
https://doi.org/10.1158/0008-5472.22419317
Autor:
Anthony J. Chalmers, Michael F. Olson, Martin Drysdale, Heather J. McKinnon, Justin Bower, William M. Holmes, Mairi Sime, Patricia McConnell, Alexander W. Schüttelkopf, Duncan McArthur, Mokdad Mezna, Jennifer Konczal, Christopher H. Gray, Kathryn Gill, Diane Crighton, Daniel R. Croft, Abdulrahman Hussain Qaisi, Richa Vasan, Ariadni Kouzeli, Laura McDonald, Antoine Vallatos, Lesley Gilmour, Karen Strathdee, Joanna L. Birch
Subconfluent migration assay in the presence of DMSO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::986c44f814e2891d95c9c3b803ff4c97
https://doi.org/10.1158/0008-5472.22419305
https://doi.org/10.1158/0008-5472.22419305
Autor:
Anthony J. Chalmers, Michael F. Olson, Martin Drysdale, Heather J. McKinnon, Justin Bower, William M. Holmes, Mairi Sime, Patricia McConnell, Alexander W. Schüttelkopf, Duncan McArthur, Mokdad Mezna, Jennifer Konczal, Christopher H. Gray, Kathryn Gill, Diane Crighton, Daniel R. Croft, Abdulrahman Hussain Qaisi, Richa Vasan, Ariadni Kouzeli, Laura McDonald, Antoine Vallatos, Lesley Gilmour, Karen Strathdee, Joanna L. Birch
Antibodies used for western blotting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5c6d8b25c7081794de8e9a1e7b3976f
https://doi.org/10.1158/0008-5472.22419323.v1
https://doi.org/10.1158/0008-5472.22419323.v1
Autor:
Anthony J. Chalmers, Michael F. Olson, Martin Drysdale, Heather J. McKinnon, Justin Bower, William M. Holmes, Mairi Sime, Patricia McConnell, Alexander W. Schüttelkopf, Duncan McArthur, Mokdad Mezna, Jennifer Konczal, Christopher H. Gray, Kathryn Gill, Diane Crighton, Daniel R. Croft, Abdulrahman Hussain Qaisi, Richa Vasan, Ariadni Kouzeli, Laura McDonald, Antoine Vallatos, Lesley Gilmour, Karen Strathdee, Joanna L. Birch
untreated GFP E2 cells in an ex vivo brain slice motility assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d2229e8e63240375703ff0fb6d4532
https://doi.org/10.1158/0008-5472.22419314
https://doi.org/10.1158/0008-5472.22419314