Zobrazeno 1 - 10
of 184
pro vyhledávání: '"Heather H Cheng"'
Autor:
Laura S Graham, Bruce Montgomery, Heather H Cheng, Evan Y Yu, Peter S Nelson, Colin Pritchard, Stephanie Erickson, Ajjai Alva, Michael T Schweizer
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0233260 (2020)
BACKGROUND:While response rates to anti-PD1 therapy are low in unselected metastatic castration resistant prostate cancer (mCRPC) patients, those with inactivating mutations in mismatch repair (MMR) genes (i.e. MMR deficiency; MMRd) or microsatellite
Externí odkaz:
https://doaj.org/article/72aa76cc3eb9475eb65eaa44e2277623
Autor:
Alexander S Carlson, Rigo I Acevedo, Daniel M Lim, Roman Gulati, Agnes Gawne, Alexandra O Sokolova, Heather H Cheng, Peter S Nelson, R Bruce Montgomery, Evan Y Yu, Michael T Schweizer
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0239686 (2020)
IntroductionA significant proportion of patients with metastatic castration-resistant prostate cancer (mCRPC) harbor mutations in homologous recombination (HR) repair genes, with some of these mutations associating with increased tumor susceptibility
Externí odkaz:
https://doaj.org/article/f6c10cf143e14114ba66811e4329fc74
Autor:
Michael T Schweizer, Kathleen Haugk, Jožefa S McKiernan, Roman Gulati, Heather H Cheng, Jessica L Maes, Ruth F Dumpit, Peter S Nelson, Bruce Montgomery, Jeannine S McCune, Stephen R Plymate, Evan Y Yu
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0198389 (2018)
BACKGROUND:Niclosamide, an FDA-approved anti-helminthic drug, has activity in preclinical models of castration-resistant prostate cancer (CRPC). Potential mechanisms of action include degrading constitutively active androgen receptor splice variants
Externí odkaz:
https://doaj.org/article/f9580013a67f4ac696bef5949286bdea
Autor:
Michael T Schweizer, Kathleen Haugk, Jožefa S McKiernan, Roman Gulati, Heather H Cheng, Jessica L Maes, Ruth F Dumpit, Peter S Nelson, Bruce Montgomery, Jeannine S McCune, Stephen R Plymate, Evan Y Yu
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0202709 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0198389.].
Externí odkaz:
https://doaj.org/article/b39a0a762e51418db081ff1e29182883
Publikováno v:
Asian Journal of Andrology, Vol 16, Iss 3, Pp 354-358 (2014)
Glucocorticoids have been used in the treatment of prostate cancer to slow disease progression, improve pain control and offset side effects of chemo- and hormonal therapy. However, they may also have the potential to drive prostate cancer growth via
Externí odkaz:
https://doaj.org/article/6fe7203c62c34ec0a5a3f1021a712229
Autor:
Amy E. Leader, Timothy R. Rebbeck, William K. Oh, Alpa V. Patel, Eric P. Winer, LeeAnn O. Bailey, Leonard G. Gomella, Crystal Y. Lumpkins, Isla P. Garraway, Lisa B. Aiello, Monica L. Baskin, Heather H. Cheng, Kathleen A. Cooney, Amanda Ganzak, Daniel J. George, Susan Halabi, Feighanne Hathaway, Claire Healy, Joseph W. Kim, Michael S. Leapman, Stacy Loeb, Kara N. Maxwell, Christopher McNair, Todd M. Morgan, Breanne Prindeville, Howard R. Soule, Whitney L. Steward, Sakinah C. Suttiratana, Mary-Ellen Taplin, Kosj Yamoah, Thierry Fortune, Kris Bennett, Joshua Blanding-Godbolt, Laura Gross, Veda N. Giri
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Black men consistently have higher rates of prostate cancer (PCA)- related mortality. Advances in PCA treatment, screening, and hereditary cancer assessment center around germline testing (GT). Of concern is the significant under-
Externí odkaz:
https://doaj.org/article/7a481f2b8f7f4858987d88a4639dee1d
Autor:
Azra Ajkunic, Erolcan Sayar, Martine P. Roudier, Radhika A. Patel, Ilsa M. Coleman, Navonil De Sarkar, Brian Hanratty, Mohamed Adil, Jimmy Zhao, Samir Zaidi, Lawrence D. True, Jamie M. Sperger, Heather H. Cheng, Evan Y. Yu, Robert B. Montgomery, Jessica E. Hawley, Gavin Ha, Thomas Persse, Patricia Galipeau, John K. Lee, Stephanie A. Harmon, Eva Corey, Joshua M. Lang, Charles L. Sawyers, Colm Morrissey, Michael T. Schweizer, Roman Gulati, Peter S. Nelson, Michael C. Haffner
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-9 (2024)
Abstract Therapeutic approaches targeting proteins on the surface of cancer cells have emerged as an important strategy for precision oncology. To capitalize on the potential impact of drugs targeting surface proteins, detailed knowledge about the ex
Externí odkaz:
https://doaj.org/article/cdd085eaf0e84556a25f843f3b873e3c
Autor:
Heather H Cheng, Hye Son Yi, Yeonju Kim, Evan M Kroh, Jason W Chien, Keith D Eaton, Marc T Goodman, Jonathan F Tait, Muneesh Tewari, Colin C Pritchard
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e64795 (2013)
Circulating, cell-free microRNAs (miRNAs) are promising candidate biomarkers, but optimal conditions for processing blood specimens for miRNA measurement remain to be established. Our previous work showed that the majority of plasma miRNAs are likely
Externí odkaz:
https://doaj.org/article/fd1a599a5df941fa8dff043b91cc94a3
Autor:
Heather H Cheng, Patrick S Mitchell, Evan M Kroh, Alexander E Dowell, Lisly Chéry, Javed Siddiqui, Peter S Nelson, Robert L Vessella, Beatrice S Knudsen, Arul M Chinnaiyan, Kenneth J Pienta, Colm Morrissey, Muneesh Tewari
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69239 (2013)
MicroRNAs (miRNAs) are small (∼22 nucleotide) non-coding RNAs that regulate a myriad of biological processes and are frequently dysregulated in cancer. Cancer-associated microRNAs have been detected in serum and plasma and hold promise as minimally
Externí odkaz:
https://doaj.org/article/af26385633a64c4d884f79de8a2af0c1
Autor:
Dimitrios Makrakis, Jonathan L. Wright, Martine P. Roudier, Jose Garcia, Funda Vakar-Lopez, Michael P. Porter, Yan Wang, Atreya Dash, Daniel Lin, George Schade, Brian Winters, Xiotun Zhang, Peter Nelson, Elahe Mostaghel, Heather H. Cheng, Michael Schweizer, Sarah K. Holt, John L. Gore, Evan Y. Yu, Hung Ming Lam, Bruce Montgomery
Publikováno v:
Clinical Genitourinary Cancer. 21:265-272
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90e8d4c8c24d4e9511cd699acda86499
https://doi.org/10.1016/j.clgc.2022.12.003
https://doi.org/10.1016/j.clgc.2022.12.003