Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Heather H, Zhou"'
Autor:
Sharon, Jensen-Cody, Erin S, Coyne, Xunshan, Ding, Anu, Sebin, Jen, Vogel, Jaclyn, Goldstein, Thomas W, Rosahl, Heather H, Zhou, Hugues, Jacobs, Marie-France, Champy, Ghina Bou, About, Saswata, Talukdar, Yingjiang, Zhou
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 322:E517-E527
Insulin resistance is a major public health burden that often results in other comorbidities including type 2 diabetes, nonalcoholic fatty liver disease (NAFLD), and cardiovascular disease. An insulin sensitizer has the potential to become a disease-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7b12db4b6eb905c97891845c18f73eb
https://doi.org/10.1152/ajpendo.00161.2021
https://doi.org/10.1152/ajpendo.00161.2021
Autor:
Heather H Zhou, Eric A. Gulve, William J. Salsgiver, Yi Luo, Violand Bernard N, Xiaomin Song, Mike Briggs
Publikováno v:
Biochemical and biophysical research communications. 338(2)
Adiponectin plays important roles in regulating insulin sensitivity and atherogenesis. Adiponectin has been shown to suppress hepatic glucose production in rodents. It has not been reported whether ectopically expressed adiponectin could regulate glu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ade69c74b6ea6b5f89aa112293b3de41
https://pubmed.ncbi.nlm.nih.gov/16236252
https://pubmed.ncbi.nlm.nih.gov/16236252
Publikováno v:
Chemistry & Biology. (5):609-618
Natural and synthetic bioactive small molecules form the backbone of modern therapeutics. These drugs primarily exert their effect by targeting cellular host or foreign proteins that are critical for the progression of disease. Therefore, a crucial s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b38645cb1a273a518a301448174b5aa
Autor:
Bettano K; Translational Imaging. Electronic address: kimberly_bettano@merck.com., Zielstorff M; Quantitative Biosciences., Sevilla R; Translational Imaging., Yang R; Quantitative Biosciences., Zhou H; Genome and Biomarker Sciences, Merck & Co., Inc., Kenilworth, NJ, USA., Rosahl T; Quantitative Biosciences., Zhang-Hoover J; Quantitative Biosciences., Moy LY; Quantitative Biosciences., Zhang W; Translational Imaging. Electronic address: weisheng.zhang@Takeda.com.
Publikováno v:
Neoplasia (New York, N.Y.) [Neoplasia] 2022 May; Vol. 27, pp. 100781. Date of Electronic Publication: 2022 Apr 02.
Autor:
Tian Y; Neuroscience, MRL, Merck & Co., Inc, 770 Sumneytown Pike, West Point, PA 19486, USA. Electronic address: yuan.tian1@merck.com., Wang Y; Neuroscience, MRL, Merck & Co., Inc, 770 Sumneytown Pike, West Point, PA 19486, USA., Jablonski AM; Neuroscience, MRL, Merck & Co., Inc, 770 Sumneytown Pike, West Point, PA 19486, USA., Hu Y; Neuroscience, MRL, Merck & Co., Inc, 770 Sumneytown Pike, West Point, PA 19486, USA., Sugam JA; Neuroscience, MRL, Merck & Co., Inc, 770 Sumneytown Pike, West Point, PA 19486, USA., Koglin M; Mass Spectrometry & Biophysics, MRL, Merck & Co., Inc, 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA., Stachel SJ; Chemistry, MRL, Merck & Co., Inc, 770 Sumneytown Pike, West Point, PA 19486, USA., Zhou H; Genetics and Pharmacogenomics, MRL, Merck & Co., Inc, 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA., Uslaner JM; Neuroscience, MRL, Merck & Co., Inc, 770 Sumneytown Pike, West Point, PA 19486, USA., Parmentier-Batteur S; Neuroscience, MRL, Merck & Co., Inc, 770 Sumneytown Pike, West Point, PA 19486, USA.
Publikováno v:
Neurobiology of disease [Neurobiol Dis] 2021 Dec; Vol. 161, pp. 105548. Date of Electronic Publication: 2021 Nov 06.
Autor:
Jablonski AM; Neuroscience, MRL, Merck & Co., Inc, 770 Sumneytown Pike, West Point, PA, 19486, USA. angela.jablonski@merck.com., Warren L; Neuroscience, MRL, Merck & Co., Inc, 770 Sumneytown Pike, West Point, PA, 19486, USA., Usenovic M; Neuroscience, MRL, Merck & Co., Inc, 770 Sumneytown Pike, West Point, PA, 19486, USA., Zhou H; Genetics and Pharmacogenomics, MRL, Merck & Co., Inc, 2000 Galloping Hill Rd, Kenilworth, NJ, 07033, USA., Sugam J; Neuroscience, MRL, Merck & Co., Inc, 770 Sumneytown Pike, West Point, PA, 19486, USA., Parmentier-Batteur S; Neuroscience, MRL, Merck & Co., Inc, 770 Sumneytown Pike, West Point, PA, 19486, USA., Voleti B; Neuroscience, MRL, Merck & Co., Inc, 770 Sumneytown Pike, West Point, PA, 19486, USA. bhavya.voleti@merck.com.
Publikováno v:
Scientific reports [Sci Rep] 2021 Feb 09; Vol. 11 (1), pp. 3438. Date of Electronic Publication: 2021 Feb 09.
Autor:
Aslamkhan AG; Safety Assessment & Laboratory Animal Resources, Merck & Co, Inc., West Point, PA, USA; 770 Sumneytown Pike, WP45-313; West Point, PA 19486, USA. Electronic address: amy_aslamkhan@merck.com., Xu Q; Safety Assessment & Laboratory Animal Resources, Merck & Co, Inc., West Point, PA, USA., Loughlin A; Safety Assessment & Laboratory Animal Resources, Merck & Co, Inc., West Point, PA, USA., Vu H; Safety Assessment & Laboratory Animal Resources, Merck & Co, Inc., West Point, PA, USA., Pacchione S; Safety Assessment & Laboratory Animal Resources, Merck & Co, Inc., West Point, PA, USA., Bhatt B; Safety Assessment & Laboratory Animal Resources, Merck & Co, Inc., West Point, PA, USA., Garfinkel I; Safety Assessment & Laboratory Animal Resources, Merck & Co, Inc., West Point, PA, USA., Styring TG; Safety Assessment & Laboratory Animal Resources, Merck & Co, Inc., West Point, PA, USA., LaFranco-Scheuch L; Safety Assessment & Laboratory Animal Resources, Merck & Co, Inc., West Point, PA, USA., Pearson K; Safety Assessment & Laboratory Animal Resources, Merck & Co, Inc., West Point, PA, USA., Reynolds S; Safety Assessment & Laboratory Animal Resources, Merck & Co, Inc., West Point, PA, USA., Li N; Safety Assessment & Laboratory Animal Resources, Merck & Co, Inc., West Point, PA, USA., Zhou H; Genetics and Pharmacogenomics, Merck & Co, Inc., Kenilworth, NJ, USA., Miller JR; Quantitative Biosciences, Merck & Co, Inc., Boston, MA, USA., Solban N; Quantitative Biosciences, Merck & Co, Inc., Boston, MA, USA., Bass A; Safety Assessment & Laboratory Animal Resources, Merck & Co, Inc., West Point, PA, USA., Glaab WE; Safety Assessment & Laboratory Animal Resources, Merck & Co, Inc., West Point, PA, USA.
Publikováno v:
Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2020 Nov 01; Vol. 406, pp. 115216. Date of Electronic Publication: 2020 Aug 29.
Publikováno v:
JCI insight [JCI Insight] 2019 Aug 08; Vol. 4 (15). Date of Electronic Publication: 2019 Aug 08 (Print Publication: 2019).
Autor:
Chaurasia B; Department of Nutrition and Integrative Physiology and the Diabetes and Metabolism Research Center, University of Utah, Salt Lake City, UT 84112, USA., Tippetts TS; Department of Nutrition and Integrative Physiology and the Diabetes and Metabolism Research Center, University of Utah, Salt Lake City, UT 84112, USA., Mayoral Monibas R; Merck Research Laboratories, Merck, Kenilworth, NJ 07033, USA., Liu J; Merck Research Laboratories, Merck, Kenilworth, NJ 07033, USA., Li Y; Department of Nutrition and Integrative Physiology and the Diabetes and Metabolism Research Center, University of Utah, Salt Lake City, UT 84112, USA., Wang L; Department of Nutrition and Integrative Physiology and the Diabetes and Metabolism Research Center, University of Utah, Salt Lake City, UT 84112, USA., Wilkerson JL; Department of Nutrition and Integrative Physiology and the Diabetes and Metabolism Research Center, University of Utah, Salt Lake City, UT 84112, USA., Sweeney CR; Department of Nutrition and Integrative Physiology and the Diabetes and Metabolism Research Center, University of Utah, Salt Lake City, UT 84112, USA., Pereira RF; School of Dentistry, São Paulo State University (UNESP), Araçatuba 16015, Brazil., Sumida DH; School of Dentistry, São Paulo State University (UNESP), Araçatuba 16015, Brazil., Maschek JA; Department of Biochemistry and the Diabetes and Metabolism Research Center, University of Utah, Salt Lake City, UT 84112, USA., Cox JE; Department of Biochemistry and the Diabetes and Metabolism Research Center, University of Utah, Salt Lake City, UT 84112, USA., Kaddai V; Department of Nutrition and Integrative Physiology and the Diabetes and Metabolism Research Center, University of Utah, Salt Lake City, UT 84112, USA., Lancaster GI; Baker IDI Heart and Diabetes Institute, Melbourne, Victoria 3004, Australia., Siddique MM; Faculty of Science, University of Brunei Darussalam, Gadong 1410, Brunei Darussalam., Poss A; Department of Nutrition and Integrative Physiology and the Diabetes and Metabolism Research Center, University of Utah, Salt Lake City, UT 84112, USA., Pearson M; Sciex, Framingham, MA 01701, USA., Satapati S; Merck Research Laboratories, Merck, Kenilworth, NJ 07033, USA., Zhou H; Merck Research Laboratories, Merck, Kenilworth, NJ 07033, USA., McLaren DG; Merck Research Laboratories, Merck, Kenilworth, NJ 07033, USA., Previs SF; Merck Research Laboratories, Merck, Kenilworth, NJ 07033, USA., Chen Y; Merck Research Laboratories, Merck, Kenilworth, NJ 07033, USA., Qian Y; Merck Research Laboratories, Merck, Kenilworth, NJ 07033, USA., Petrov A; Merck Research Laboratories, Merck, Kenilworth, NJ 07033, USA., Wu M; Merck Research Laboratories, Merck, Kenilworth, NJ 07033, USA., Shen X; Merck Research Laboratories, Merck, Kenilworth, NJ 07033, USA., Yao J; Merck Research Laboratories, Merck, Kenilworth, NJ 07033, USA., Nunes CN; Merck Research Laboratories, Merck, Kenilworth, NJ 07033, USA., Howard AD; Merck Research Laboratories, Merck, Kenilworth, NJ 07033, USA., Wang L; Merck Research Laboratories, Merck, Kenilworth, NJ 07033, USA., Erion MD; Merck Research Laboratories, Merck, Kenilworth, NJ 07033, USA., Rutter J; Department of Biochemistry and the Diabetes and Metabolism Research Center, University of Utah, Salt Lake City, UT 84112, USA.; Howard Hughes Medical Institute, Salt Lake City, UT 84112, USA., Holland WL; Department of Nutrition and Integrative Physiology and the Diabetes and Metabolism Research Center, University of Utah, Salt Lake City, UT 84112, USA., Kelley DE; Merck Research Laboratories, Merck, Kenilworth, NJ 07033, USA., Summers SA; Department of Nutrition and Integrative Physiology and the Diabetes and Metabolism Research Center, University of Utah, Salt Lake City, UT 84112, USA. scott.a.summers@health.utah.edu.
Publikováno v:
Science (New York, N.Y.) [Science] 2019 Jul 26; Vol. 365 (6451), pp. 386-392. Date of Electronic Publication: 2019 Jul 04.
Autor:
Xie J; Horae Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA 01605, USA; Viral Vector Core, University of Massachusetts Medical School, Worcester, MA 01605, USA; Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, MA 01605, USA., Mao Q; Horae Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA 01605, USA; Department of Thoracic Cancer, Cancer Center, West China Hospital, West China School of Clinical Medicine, Sichuan University, Chengdu, Sichuan 610000, China., Tai PWL; Horae Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA 01605, USA; Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, MA 01605, USA., He R; Horae Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA 01605, USA; Viral Vector Core, University of Massachusetts Medical School, Worcester, MA 01605, USA., Ai J; Horae Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA 01605, USA; Urology Department, West China Hospital, Sichuan University, Chengdu, Sichuan 610000, China., Su Q; Horae Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA 01605, USA; Viral Vector Core, University of Massachusetts Medical School, Worcester, MA 01605, USA., Zhu Y; Horae Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA 01605, USA; Department of Cardiovascular Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan 610000, China., Ma H; Horae Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA 01605, USA; Viral Vector Core, University of Massachusetts Medical School, Worcester, MA 01605, USA., Li J; Horae Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA 01605, USA., Gong S; Horae Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA 01605, USA., Wang D; Horae Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA 01605, USA; Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, MA 01605, USA., Gao Z; Horae Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA 01605, USA., Li M; Horae Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA 01605, USA; Viral Vector Core, University of Massachusetts Medical School, Worcester, MA 01605, USA., Zhong L; Horae Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA 01605, USA., Zhou H; Genetics and Pharmacogenomics, Merck Research Laboratory, Kenilworth, NJ 07033, USA. Electronic address: hui_zhou@merck.com., Gao G; Horae Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA 01605, USA; Viral Vector Core, University of Massachusetts Medical School, Worcester, MA 01605, USA; Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, MA 01605, USA; State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan 610000, China. Electronic address: guangping.gao@umassmed.edu.
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2017 Jun 07; Vol. 25 (6), pp. 1363-1374. Date of Electronic Publication: 2017 Apr 24.