Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Heather H, Shih"'
Autor:
Andrew C. Lake, Ying Sun, Jian-Liang Li, Jae Eun Kim, Jeremy W. Johnson, Dongmei Li, Tracy Revett, Heather H. Shih, Wei Liu, Janet E. Paulsen, Ruth E. Gimeno
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 11, Pp 2477-2487 (2005)
Adiponutrin and a related protein, adipocyte triglyceride lipase (ATGL; also known as Desnutrin), were recently described as adipocyte-specific proteins with lipid hydrolase activity. Using bioinformatics, we identified three additional Adiponutrin f
Externí odkaz:
https://doaj.org/article/09fedfe3c89c48ca8cf81c5bd1aa3a66
Autor:
Renee Ramsey, Sri Laxmanan, Orla Cunningham, Lydia Mosyak, Brian J. Fennell, Joel Bard, Steven P. Braithwaite, Bénédicte Autin, Chao Tu, Christopher John Corcoran, Anne S. Klein, Edward R. Lavallie, Leeying Wu, Wei Cao, Eugenia Kouranova, Heather H. Shih, Anthony J. Milici, William J.J. Finlay, Janet E. Paulsen, Jo Ann Dumin, Deirdre Ní Shúilleabháin, Matthew Allister Lambert, Maya Arai, Mostafa Ait-Zahra, Davinder Gill
Publikováno v:
Journal of Biological Chemistry. 287:44425-44434
Highly specific antibodies to phosphoepitopes are valuable tools to study phosphorylation in disease states, but their discovery is largely empirical, and the molecular mechanisms mediating phosphospecific binding are poorly understood. Here, we repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e527a805643d52b9e49f16ee3c80cdac
https://doi.org/10.1074/jbc.m112.415935
https://doi.org/10.1074/jbc.m112.415935
Autor:
Heather H. Shih, Janet E. Paulsen, Kim Marquette, Robert Martone, Stephane Olland, Davinder Gill, Zhijian Lu, Tao He, Eric Sousa
Publikováno v:
International Journal of Mass Spectrometry. 312:61-69
A novel mass spectrometry-based workflow for de novo sequencing of a full-length monoclonal antibody (LB509) against α-synuclein is presented. This approach combines chemical modification of cysteine residues, multiple enzymatic digestion, stable is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6075b36a33a07c4f791b207f03409bfe
https://doi.org/10.1016/j.ijms.2011.05.005
https://doi.org/10.1016/j.ijms.2011.05.005
Publikováno v:
American Journal of Physiology-Cell Physiology. 298:C1180-C1187
Oxidatively modified low-density lipoprotein (OxLDL) is a contributing factor of endothelial dysfunction, an early cellular event during atherogenesis. In endothelial cells, OxLDL has been shown to stimulate proinflammatory responses, increase lipid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ee53d7c475fe43a0e906930b233dff0
https://doi.org/10.1152/ajpcell.00483.2009
https://doi.org/10.1152/ajpcell.00483.2009
Autor:
Janet E. Paulsen, Zhijian Lu, Grace Yan, Jocelyn Sanford, Heather H. Shih, Adam Reid Root, Khetemenee Lam, Douglas C Harnish, Richard Zollner, Wei Cao, Lioudmila Tchistiakova, Mostafa Ait-Zahra, Valerie Calabro, Rita Agostinelli, Stephane Olland, Davinder Gill, Angela Robak
Publikováno v:
FEBS Journal. 276:4909-4920
LOX-1 is a scavenger receptor that functions as the primary receptor for oxidized low-density lipoprotein (OxLDL) in endothelial cells. The binding of OxLDL to LOX-1 is believed to lead to endothelial activation, dysfunction, and injury, which consti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f02942f24cebe8e4a9b6be49bf5a02f0
https://doi.org/10.1111/j.1742-4658.2009.07190.x
https://doi.org/10.1111/j.1742-4658.2009.07190.x
Autor:
Leo M. Albert, James C. Keith, Kathleen M. Shields, Vasu Maganti, George P. Vlasuk, Jeffrey L. Feldman, Gustave T. Hebert, Debra D. Pittman, Heather H. Shih, Anthony Wong, Janet E. Paulsen, Aaron Winkler, Christine Resmini, Valerie Clerin, Nanhua Deng
Publikováno v:
Atherosclerosis. 201:53-66
Objective The present study was conducted to characterize the expression of the cysteine protease legumain in murine and human atherosclerotic tissues, and to explore the molecular mechanisms by which legumain may contribute to the pathophysiology of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de79f0d454c897c1aff6db80aae92f23
https://doi.org/10.1016/j.atherosclerosis.2008.01.016
https://doi.org/10.1016/j.atherosclerosis.2008.01.016
Autor:
Wenyan Zhong, Ying Sun, Christine Huard, Eugene L. Brown, Janet E. Paulsen, Stephen P. Berasi, Heather H. Shih, Dongmei Li, Ruth E. Gimeno, Robert V. Martinez
Publikováno v:
Journal of Biological Chemistry. 281:27167-27177
Increased hepatic gluconeogenesis is an important contributor to the fasting hyperglycemia found in Type 2 diabetic patients. Low energy states activate the intracellular energy sensor AMP-activated kinase (AMPK). AMPK activation by the AMP mimetic A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d0a6843e0b4d527c339a9ba54cc0a9b
https://doi.org/10.1074/jbc.m602416200
https://doi.org/10.1074/jbc.m602416200
Autor:
Jian-Liang Li, Andrew C. Lake, Ying Sun, Dongmei Li, Wei Liu, Tracy Revett, Heather H. Shih, Janet E. Paulsen, Jeremy Johnson, Jae Eun Kim, Ruth E. Gimeno
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 11, Pp 2477-2487 (2005)
Adiponutrin and a related protein, adipocyte triglyceride lipase (ATGL; also known as Desnutrin), were recently described as adipocyte-specific proteins with lipid hydrolase activity. Using bioinformatics, we identified three additional Adiponutrin f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abb6dbf9c6c130adba69e5d6a35b5c57
https://doi.org/10.1194/jlr.m500290-jlr200
https://doi.org/10.1194/jlr.m500290-jlr200
Autor:
Andrew B. Leiter, Stephen P. Berasi, K. Eric Paulson, Ellen M. Sampson, Mei Xiu, Amy S. Yee, Heather H. Shih
Publikováno v:
Molecular and Cellular Biology. 21:5723-5732
We previously isolated HBP1 as a target of the retinoblastoma (RB) and p130 family members and as the first of the HMG box transcriptional repressors. Our subsequent work demonstrated that HBP1 coordinates differentiation in cell culture models. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b115c1b3078f92c138db9e9af6e4b0d
https://doi.org/10.1128/mcb.21.17.5723-5732.2001
https://doi.org/10.1128/mcb.21.17.5723-5732.2001
Publikováno v:
Biopolymers. 38:367-376
Pulse gel electrophoresis was used to measure the reduction of mobilities of λ-DNA-Hind III fragments ranging from 23.130 to 2.027 kilobase pairs in Tris borate buffer solutions mixed with either hexammine cobalt(III), or spermidine3+ trivalent coun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d70714472fae8375ea1099d2bd334442
https://doi.org/10.1002/(sici)1097-0282(199603)38:3<367::aid-bip9>3.0.co
https://doi.org/10.1002/(sici)1097-0282(199603)38:3<367::aid-bip9>3.0.co