Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Heather Friberg"'
Autor:
Sanja Mandaric, Heather Friberg, Xavier Saez-Llorens, Charissa Borja-Tabora, Shibadas Biswal, Ian Escudero, Alice Faccin, Raphael Gottardo, Manja Brose, Nicholas Roubinis, Darlene Fladager, Rodrigo DeAntonio, Julie Anne L. Dimero, Nathali Montenegro, Nicolas Folschweiller, Jeffrey R. Currier, Mayuri Sharma, Vianney Tricou
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-13 (2024)
Abstract As robust cellular responses are important for protection against dengue, this phase 2 study evaluated the kinetics and phenotype of T cell responses induced by TAK-003, a live-attenuated tetravalent dengue vaccine, in 4–16-year-old living
Externí odkaz:
https://doaj.org/article/3b801d6feac84345ad976ff7208a2eac
Autor:
Heather Friberg, Morgan Gargulak, Amanda Kong, Leyi Lin, Luis J. Martinez, Alexander C. Schmidt, Robert M. Paris, Richard G. Jarman, Clemente Diaz, Stephen J. Thomas, Philippe Moris, Jeffrey R. Currier
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-10 (2022)
Abstract The increasing global impact of dengue underscores the need for a dengue virus (DENV) vaccine. We assessed B-cell and T-cell responses following vaccination with four formulations of a tetravalent dengue purified inactivated vaccine (DPIV) i
Externí odkaz:
https://doaj.org/article/2046e228a49043bda2bf6939924cdb61
Autor:
Irina Maljkovic Berry, Jun Hang, Christian Fung, Yu Yang, Marcus Chibucos, Adam Pollio, Jay Gandhi, Tao Li, Matthew A. Conte, Grace M. Lidl, Jay A. Johannigman, Heather Friberg
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-9 (2022)
Abstract Background With the emergence and spread of SARS-CoV-2 variants, genomic epidemiology and surveillance have proven invaluable tools for variant tracking. Here, we analyzed SARS-CoV-2 samples collected from personnel located at the US/NATO ba
Externí odkaz:
https://doaj.org/article/03df28613a1747f2b00372bffdd5fc30
Autor:
Michael K. McCracken, Caitlin H. Kuklis, Chandrika B. Kannadka, David A. Barvir, Mark A. Sanborn, Adam T. Waickman, Hayden C. Siegfried, Kaitlin A. Victor, Kristin L. Hatch, Rafael De La Barrera, Shannon D. Walls, Wiriya Rutvisuttinunt, Jeffrey R. Currier, Heather Friberg, Richard G. Jarman, Gregory D. Gromowski
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-12 (2021)
Abstract Antibody-dependent enhancement (ADE) is suspected to influence dengue virus (DENV) infection, but the role ADE plays in vaccination strategies incorporating live attenuated virus components is less clear. Using a heterologous prime-boost str
Externí odkaz:
https://doaj.org/article/d8ee938ae9d948e0b132ccac35634eaa
Autor:
Adam T. Waickman, Kaitlin Victor, Krista Newell, Tao Li, Heather Friberg, Kathryn E. Foulds, Mario Roederer, Diane L. Bolton, Jeffrey R. Currier, Robert Seder
Publikováno v:
JCI Insight, Vol 7, Iss 13 (2022)
Vaccine-elicited SARS-CoV-2 antibody responses are an established correlate of protection against viral infection in humans and nonhuman primates. However, it is less clear that vaccine-induced immunity is able to limit infection-elicited inflammatio
Externí odkaz:
https://doaj.org/article/e4e7681338584bf98cc3b00823799e77
Autor:
Adam D. Wegman, Hengsheng Fang, Alan L. Rothman, Stephen J. Thomas, Timothy P. Endy, Michael K. McCracken, Jeffrey R. Currier, Heather Friberg, Gregory D. Gromowski, Adam T. Waickman
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Dengue virus (DENV) is a prevalent human pathogen, infecting approximately 400 million individuals per year and causing symptomatic disease in approximately 100 million. A distinct feature of dengue is the increased risk for severe disease in some in
Externí odkaz:
https://doaj.org/article/4682c9b4478a45098e43e2013851ecef
Autor:
Hung D. Nguyen, Sidhartha Chaudhury, Adam T. Waickman, Heather Friberg, Jeffrey R. Currier, Anders Wallqvist
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The dengue virus circulates as four distinct serotypes, where a single serotype infection is typically asymptomatic and leads to acquired immunity against that serotype. However, the developed immunity to one serotype is thought to underlie the sever
Externí odkaz:
https://doaj.org/article/5570f83ee3c740fbbd66a66cd3b5f949
Autor:
Luis Alberto Sanchez-Vargas, Kathryn B. Anderson, Anon Srikiatkhachorn, Jeffrey R. Currier, Heather Friberg, Timothy P. Endy, Stefan Fernandez, Anuja Mathew, Alan L. Rothman
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Memory T cells resulting from primary dengue virus (DENV) infection are hypothesized to influence the clinical outcome of subsequent DENV infection. However, the few studies involving prospectively collected blood samples have found weak and inconsis
Externí odkaz:
https://doaj.org/article/33578c737cb049738c7f28f97e47cd81
Autor:
Philippe Moris, Kristen M. Bauer, Jeffrey R. Currier, Heather Friberg, Kenneth H. Eckels, Ines O. Esquilin, Robert V. Gibbons, Bruce L. Innis, Richard G. Jarman, Sriluck Simasathien, Peifang Sun, Stephen J. Thomas, Veerachai Watanaveeradej
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 15, Iss 9, Pp 2090-2105 (2019)
Three phase II randomized trials evaluated the safety/immunogenicity of two formulations of live-attenuated tetravalent dengue virus (TDEN) vaccine in dengue-endemic (Puerto Rico, Thailand) and non-endemic (US) regions (NCT00350337/NCT00370682/NCT004
Externí odkaz:
https://doaj.org/article/85423c0ddbfe4ec1a2141fd243dc8b6b
Autor:
Adam T. Waickman, Kaitlin Victor, Tao Li, Kristin Hatch, Wiriya Rutvisuttinunt, Carey Medin, Benjamin Gabriel, Richard G. Jarman, Heather Friberg, Jeffrey R. Currier
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Using a combination of single-cell RNA sequencing and TCR clonotype analysis on longitudinal samples from dengue vaccinated individuals, Waickman et al. here define a transcriptional signature in acutely-activated T cells that is associated with dura
Externí odkaz:
https://doaj.org/article/397665ccccdd42deb850a4519fa9b750