Evaluating Eosinophilic Colitis as a Unique Disease Using Colonic Molecular Profiles: A Multi-Site Study

Autor: Tetsuo Shoda, Margaret H. Collins, Mark Rochman, Ting Wen, Julie M. Caldwell, Lydia E. Mack, Garrett A. Osswald, John A. Besse, Yael Haberman, Seema S. Aceves, Nicoleta C. Arva, Kelley E. Capocelli, Mirna Chehade, Carla M. Davis, Evan S. Dellon, Gary W. Falk, Nirmala Gonsalves, Sandeep K. Gupta, Ikuo Hirano, Paneez Khoury, Amy Klion, Calies Menard-Katcher, John Leung, Vincent A. Mukkada, Philip E. Putnam, Jonathan M. Spergel, Joshua B. Wechsler, Guang-Yu Yang, Glenn T. Furuta, Lee A. Denson, Marc E. Rothenberg, J. Pablo Abonia, Seema Aceves, Samuel Almonte, Rachel Andrews, Sara Anvari, Ashley Arrington, Nicoleta Arva, Fred Atkins, Dominique Bailey, Alexis Berry, Bridget Besl, Scott Bolton, Peter Bonis, Wendy Book, Kimberly Bray, Teresa Brown, Cassandra Burger, Deirdre Burke, Jonathon Cahoon, Kelley Capocelli, Eric Chiou, Margaret Collins, Carla Davis, Evan Dellon, Maureen DeMarshall, Lauren DiTommaso, Ranjan Dohil, Michael Eby, Gary Falk, David Fleischer, Heather Foote, Kelci Foss, Joel Friedlander, Patricia Fulkerson, Glenn Furuta, Debra Geno, Thomas Greuter, Sandeep Gupta, Frank Hamilton, Kirk Harris, Jennifer Harris, Girish Hiremath, Nicole Holland-Thomas, Lea Jacinto, Amir Kagalwalla, Timothy Kaseta, David Katzka, Kaitlin Keeley, Emad Khosh-Hemmat, Eileen King, Kara Kliewer, Jennifer Knowles, Kendra Kocher, Ellyn Kodroff, Jeffrey Krischer, Shay Kyle, Meredith Levy, Chris Liacouras, Denise Mack, Lisa Martin, Ellen Martin, Talaya McCright-Gill, Paul Menard-Katcher, Gabriela Mendoza, Melissa Mingler, Mike Minnicozzi, Amanda Muir, Vincent Mukkada, Cristin Murray-Petzold, Robert Newbury, Quan Nhu, Anthony Olive, Oghenekpaobor (Joel) Oyibo, Allisa Paliana, Zhaoxing Pan, Robbie Pesek, Kathryn Peterson, Heidi Poppendeck, Philip Putnam, Fabian Rivera, Marc Rothenberg, Amanda Rudman Spergel, Kathleen Sable, Alain Schoepfer, Melissa Scott, Rachel Sheridan, Selma Sinanovic, Jonathan Spergel, Mary Jo Strobel, Kiki Sun, Amy Tasco, Crystal Tholen, Katherine Thompson, Tiffany Tomkinson, Daisy Tran, Alexandra Tylicki, Tiina Urv, Mei-Lun Wang, Joshua Wechsler, Barry Wershil, Lisa Wheatley, Leah Wilkey, Angelika Zalewski, Amy Zicarelli

Publikováno v: Gastroenterology

BACKGROUND AND AIMS: Colonic eosinophilia, an enigmatic finding often referred to as eosinophilic colitis (EoC), is a poorly understood condition. Whether EoC is a distinct disease or a colonic manifestation of eosinophilic gastrointestinal diseases

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c193bddd180e12952ec18db41f3e1b0f
https://doi.org/10.1053/j.gastro.2022.01.022

Advancing patient care through the Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR)

Autor: Seema Aceves, Margaret H. Collins, Marc E. Rothenberg, Glenn T. Furuta, Nirmala Gonsalves, J. Pablo Abonia, Samuel Almonte, Rachel Andrews, Ashley Arrington, Nicoleta Arva, Fred Atkins, Dominique Bailey, Alexis Berry, Bridget Besl, Scott Bolton, Peter Bonis, Wendy Book, Kimberly Bray, Teresa Brown, Cassandra Burger, Deirdre Burke, Jonathon Cahoon, Kelley Capocelli, Mirna Chehade, Margaret Collins, Carla Davis, Evan Dellon, Maureen DeMarshall, Lauren DiTommaso, Ranjan Dohil, Michael Eby, Gary Falk, David Fleischer, Heather Foote, Kelci Foss, Joel Friedlander, Patricia Fulkerson, Glenn Furuta, Debra Geno, Thomas Greuter, Sandeep Gupta, Frank Hamilton, Kirk Harris, Jennifer Harris, Ikuo Hirano, Girish Hiremath, Nicole Holland-Thomas, Lea Jacinto, Amir Kagalwalla, Timothy Kaseta, David Katzka, Kaitlin Keeley, Emad Khosh-Hemmat, Paneez Khoury, Eileen King, Kara Kliewer, Amy Klion, Jennifer Knowles, Kendra Kocher, Ellyn Kodroff, Jeffrey Krischer, Shay Kyle, John Leung, Meredith Levy, Chris Liacouras, Denise Mack, Lisa Martin, Ellen Martin, Talaya McCright-Gill, Paul Menard-Katcher, Calies Menard-Katcher, Gabriela Mendoza, Melissa Mingler, Mike Minnicozzi, Amanda Muir, Vincent Mukkada, Cristin MurrayPetzold, Robert Newbury, Quan Nhu, Oghenekpaobor (Joel) Oyibo, Allisa Paliana, Zhaoxing Pan, Robbie Pesek, Kathryn Peterson, Heidi Poppendeck, Philip Putnam, Fabian Rivera, Marc Rothenberg, Amanda Rudman-Spergel, Kathleen Sable, Alain Schoepfer, Melissa Scott, Rachel Sheridan, Selma Sinanovic, Jonathan Spergel, MaryJo Strobel, Kiki Sun, Amy Tasco, Crystal Tholen, Katherine Thompson, Tiffany Tomkinson, Daisy Tran, Alexandra Tylicki, Tiina Urv, Mei-Lun Wang, Joshua Wechsler, Barry Wershil, Lisa Wheatley, Leah Wilkey, Guang-Yu Yang, Angelika Zalewski, Amy Zicarelli

Publikováno v: J Allergy Clin Immunol

Recent advances in rare disease research are accelerated by the work of consortia that have been supported by the National Institutes of Health. Development of such consortia rely on multidisciplinary relationships and engagement with patient advocac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bda3e0f9d8f2be3d7d4b5d58d9c8ec6
https://doi.org/10.1016/j.jaci.2019.11.012

Alignment of parent- and child-reported outcomes and histology in eosinophilic esophagitis across multiple CEGIR sites

Autor: Vincent A. Mukkada, Paul Menard-Katcher, Alicia Hurnton, Gary W. Falk, Guang Yu Yang, Wendy Book, Heather Foote, Deirdre Burke, Katherine Thompson, Eileen King, Mary Jo Strobel, Jonathan Kuhl, Ikuo Hirano, Barry K. Wershil, Denise Mack, Jeanie Bailey, Ellyn Kodroff, Allison Dubner, Melissa K. Mingler, Cathy Reidy, Kelley E. Capocelli, Susan Moist, Zhaoxing Pan, John Leung, Amanda B. Muir, Heidi Poppendeck, Maureen DeMarschall, Glenn T. Furuta, Jessi Lipscomb, Megan Lewis, John A. Besse, Melissa Scott, Margaret H. Collins, Dan Atkins, Amanda K. Rudman-Spergel, Sarah McGee, Qin Sun, Michael D. Eby, Evan S. Dellon, Marc E. Rothenberg, Sandeep K. Gupta, Kathleen Sable, Shaobo Guan, Joshua B. Wechsler, Seema S. Aceves, Nirmala Gonsalves, Christina L Carpenter, Kendra Kocher, Shay Kyle, Jeffrey P. Krischer, J. Pablo Abonia, Jonathan M. Spergel, Jacquelyn Covington, Peter A Bonis, Ashley Arrington, Ranjan Dohil, Philip E. Putnam

Publikováno v: The Journal of allergy and clinical immunology, vol 142, iss 1

BACKGROUND: Patient-reported outcome (PRO) metrics for eosinophilic esophagitis (EoE) have been developed and validated but not used in a multicenter pediatric population or systematically aligned with histology. OBJECTIVE: We sought to understand 1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db4952186deacbf67c7ecaa5c77a47ce
https://doi.org/10.1016/j.jaci.2018.05.014

Twin and family studies reveal strong environmental and weaker genetic cues explaining heritability of eosinophilic esophagitis

Autor: Vincent A. Mukkada, Kari C. Nadeau, Glenn T. Furuta, Michael D. Eby, Philip E. Putnam, Heidi Sucharew, Ajay Kaul, Evan S. Dellon, Eileen S. Alexander, Marc E. Rothenberg, Paul A. Succop, Margaret H. Collins, Alexandria J. Greenler, John B. Harley, Tommie M. Grotjan, Leah C. Kottyan, Larry E. Gurian, Karl F. von Tiehl, Heather Foote, Richard J. Noel, J. Pablo Abonia, Jeffrey G. Demain, Russell J. Hopp, Hua He, Amir F. Kagalwalla, Lisa J. Martin

Publikováno v: Journal of Allergy and Clinical Immunology. 134:1084-1092.e1

Eosinophilic esophagitis (EoE) is a chronic antigen-driven allergic inflammatory disease, likely involving the interplay of genetic and environmental factors, yet their respective contributions to heritability are unknown.To quantify the risk associa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56bb08d5ba008e57c9564af1470cbdd8
https://doi.org/10.1016/j.jaci.2014.07.021

Sex of Parent is Associated with Familial Risk of Eosinophilic Esophagitis

Autor: J.P. Abonia, M.E. Rothenberg, Michael D. Eby, Heather Foote, Eileen S. Alexander, Lisa J. Martin

Publikováno v: Journal of Allergy and Clinical Immunology. 127:AB217-AB217

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6567fc37b56313630fa93e28ec1dd8ea
https://doi.org/10.1016/j.jaci.2010.12.862