Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Heather Embree"'
Autor:
Surya Shrivastava, Paige Charlins, Amanda Ackley, Heather Embree, Boro Dropulic, Ramesh Akkina, Marc S. Weinberg, Kevin V. Morris
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 12, Iss , Pp 12-18 (2018)
Gene-based therapies represent a promising treatment for HIV-1 infection, as they offer the potential for sustained viral inhibition and reduced treatment interventions. One approach developed here involves using conditionally replicating vectors (CR
Externí odkaz:
https://doaj.org/article/e74d2a043e264b8aad17ef2026f78ab7
Autor:
Heather Embree, Marc S. Weinberg, Surya Shrivastava, Amanda Ackley, Kevin V. Morris, Ramesh Akkina, Boro Dropulic, Paige Charlins
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 12, Iss, Pp 12-18 (2018)
Molecular Therapy: Nucleic Acids, Vol 12, Iss, Pp 12-18 (2018)
Gene-based therapies represent a promising treatment for HIV-1 infection, as they offer the potential for sustained viral inhibition and reduced treatment interventions. One approach developed here involves using conditionally replicating vectors (CR
Autor:
Constantine Godellas, Patrick J. Stiff, Courtney Regan Wagner, Ann Lau Clark, Emilia R. Dellacecca, Kelli A. Hutchens, Mingli Li, Elizabeth Garrett-Mayer, Joseph I. Clark, I. Caroline Le Poole, Keisuke Shirai, Kelly M. Calabrese, Boro Dropulic, Rimas Orentas, Fernando A. Huyke, Heather Embree, Elizabeth Motunrayo Kolawole, Lance M. Hellman, Brian M. Baker, Gina Scurti, Jonathan M. Eby, Nishant K. Singh, Tamson V. Moore, Michael I. Nishimura, Brian D. Evavold, Siao Yi Wang
Publikováno v:
Cancer Immunol Immunother
Malignant melanoma incidence has been increasing for over 30 years, and despite promising new therapies, metastatic disease remains difficult to treat. We describe preliminary results from a Phase I clinical trial (NCT01586403) of adoptive cell thera
Autor:
Albert Lai, James E. Herndon, Charles G. Eberhart, Sarah Milla, Erina Yoritsune, Paula L. Griner, Jaishri O. Blakeley, Masayuki Kanamori, Charles J. Nock, Alva B. Weir, Antonio Omuro, Teiji Tominaga, Leigh Ann Bailey, Nancy Contreras, Sam Ryu, Wolfgang Wick, Kelly Wallen, Xingde Li, Lauren E. Abrey, David H. Harter, Gene H. Barnett, Glenn Stevens, Allan H. Friedman, Gabriele E. Tsung, D.M. Brown, Michael A. Vogelbaum, Ameer Abutaleb, Stefan M. Pfister, Emese Filka, T. Cloughesy, Tulika Ranjan, Andrew B. Lassman, Michael D. Prados, Serena Desideri, Timothy F. Cloughesy, Stuart A. Grossman, Eric C. Holland, Darell D. Bigner, Ryo Nishikawa, Sajeel Chowdhary, Boro Dropulic, Lisa M. DeAngelis, Shinji Kawabata, Frank Saran, Thomas J. Kaley, Warren P. Mason, Elizabeth Hovey, Shaan M. Raza, Patricia Lefferts, Amber E Kerstetter, Roger Henriksson, Cathy Brewer, William J. Garner, Lisa Rogers, Lawrence Kleinberg, Heather J. McCrea, Wenxuan Liang, Mario E. Lacouture, Elliot McVeigh, Toshihiko Kuroiwa, John Simes, Craig Nolan, Mark Rosenthal, Jeffrey H. Wisoff, Paul Rosenblatt, Hillard M. Lazarus, James J. Vredenburgh, Andrew E. Sloan, Hua Fung, Igor T. Gavrilovic, Anna K. Nowak, Olivier Chinot, Richard Schwartz, Helen Wheeler, Stacey Green, Tom Mikkelsen, David Zagzag, Michael C. Bloom, Geneviève Legault, Shin-Ichi Miyatake, Ann Livingstone, Elena Pentsova, Henry S. Friedman, Erin Hartnett, Xiaobu Ye, Katherine B. Peters, Jeffrey C. Allen, Dona Kane, Gregg Shepard, Abhay Sanan, Toshihiro Kumabe, Alfredo Quinones-Hinojosa, Tomo Miyata, Amanda Merkelson, Michael Badruddoja, Kathryn M. Field, Jessica Mavadia, Jill S. Barnholtz-Sloan, Jane S. Reese, Matthias A. Karajannis, Hugo Guerrero-Cazares, Stanton L. Gerson, Mythili Shastry, Jeremy N. Rich, Yukihiko Sonoda, Emmy Ludwig, John Sampson, Christopher L. Brown, John H. Suh, Baldassarre Stea, Heather Embree, Kate Sawkins, John D. Hainsworth, Carmen Kut, Vincent L. Giranda, Phioanh L. Nghiemphu, David T.W. Jones, Howard A. Burris, Cabaret Trial Investigators, Girish Dhall, Lawrence Cher, John A. Boockvar, Ingo K. Mellinghoff, Annick Desjardins, David M. Peereboom, Ryuta Saito, Motomasa Furuse, Jeffrey G. Supko, Yoji Yamashita, Kartik Kesavabhotla, Kent C. Shih, Andrey Korshunov, Samuel T. Chao, Marjorie Pazzi, Jeffrey A. Bacha, Bhardwaj Desai, Kurt Schroeder, Robert H. Miller, Lloyd M. Alderson, Jiefeng Xi, Rajul Shah, Naoko Takebe, Richard M. Green, Alireza Mohammad Mohammadi, Kenneth J. Cohen, Michael Fisher, Naomi E. Rance, Magalie Hilton
Publikováno v:
Neuro-Oncology. 14:vi101-vi105
Autor:
Courtney Regan Wagner, I. Caroline Le Poole, Boro Dropulic, Michael I. Nishimura, Mingli Li, Heather Embree, Jonathan M. Eby, Brian D. Evavold, Elizabeth Motunrayo Kolawole, Constantine Godellas, Fernando A. Huyke, Brian M. Baker, Keisuke Shirai, Kelly M. Calabrese, Siao Yi Wang, Lance M. Hellman, Ann Lau Clark, Emilia R. Dellacecca, Gina Scurti, Rimas Orentas, Elizabeth Garrett-Mayer, Patrick J. Stiff, Tamson V. Moore, Nishant K. Singh, Kelli A. Hutchens, Joseph I. Clark
Publikováno v:
Cancer Immunology, Immunotherapy. 67:327-327
Autor:
Jennifer E. Adair, Jahangir Ahmed, Ghassan Alusi, Doron Amit, Scott J. Antonia, Dominick L. Auci, David A. August, Rutger K. Balvers, Lajos Baranyi, Brian C. Beard, Sebastian Brennig, Elizabeth K. Broussard, Paul D. Bryson, Andrew P. Byrnes, Denise L. Cecil, Tim Chan, Charlie Comins, Christiaan R. de Vries, Robert S. DiPaola, Clemens M.F. Dirven, Mary L. Disis, Boro Dropulic, Heather Embree, Michael W. Epperly, Juan Fueyo, Toshiyoshi Fujiwara, Hua Fung, Emmanuel Gabriel, Vidya Ganapath, Stanton L. Gerson, Steven Gill, Michal Gilon, Joe Goldufsky, Candelaria Gomez-Manzano, Jennifer Rubin Grandis, Joel S. Greenberger, John W. Greiner, Maneesh Gujrati, James L. Gulley, Amin Hajitou, Kevin J. Harrington, Arash Hatefi, Loree C. Heller, Richard Heller, Akseli Hemminki, Otto Hemminki, Ronald B. Herberman, Daniel Herendeen, Abraham Hochberg, James W. Hodge, Gregory E. Holt, Ying Huang, Insoo Hyun, Hong Jiang, Shunsuke Kagawa, Zahra Karjoo, Howard Kaufman, Chien-Chih Ke, Hans-Peter Kiem, Jonathan Kimmelman, Sarah R. Klein, Shinji Kuroda, Seong Young Kwon, Nico Lachmann, Hermann Lage, Martine L.M. Lamfers, Edmund C. Lattime, Nicholas R. Lemoine, Jonathan Lewis, John B. Liao, Steven K. Libutti, Yuan Lin, Ren-Shyan Liu, Zheng-Rong Lu, Ravi A. Madan, Imad Matouk, Alan Melcher, Andrew D. Miller, Jung-Joon Min, Thomas Moritz, James J. Mulé, Atsushi Natsume, Nastasia Nianiaris, Michael I. Nishimura, Claudia Palena, Hardev Pandha, Jessica Pastoriza, Mary C. Pinder-Schenck, Sujan Piya, Elizabeth Poplin, John A. Puskas, Thomas Quinn, Ankit Rao, Jane S. Reese, Kate Relph, Juan J. Rojas, Yvonne Saenger, Jeffrey Schlom, Kevin Shannon, Shawna A. Shirley, Guy R. Simpson, Shanthi Sivendran, Vladimir Slepushkin, Sirirurg Songsivilai, Neil Steven, Sufi Mary Thomas, Steve H. Thorne, Kwong-Yok Tsang, Takashi Tsujiuchi, Toshihiko Wakabayashi, Pin Wang, Xinxin Wang, Yaohe Wang, Robert E. Weiss, Edward White, Yohsuke Yagawa, Teerapong Yata, Ming Yuan, Ziqiang Yuan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9859ecd7a8906dc1395cd68c9b25af0d
https://doi.org/10.1016/b978-0-12-394295-1.00046-9
https://doi.org/10.1016/b978-0-12-394295-1.00046-9
During the past two decades, clinical gene therapy experiences and the general advancement of biologics as a therapy have led to increasingly complex regulations and oversight of gene therapy clinical trials. The regulatory documents currently availa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac5baf1509b73aafb38fa94aeb917505
https://doi.org/10.1016/b978-0-12-394295-1.00034-2
https://doi.org/10.1016/b978-0-12-394295-1.00034-2
Autor:
Paige Charlins, Uriel A López-Lemus, Marc S. Weinberg, Amanda Ackley, Heather Embree, Kevin V. Morris, Sheena Saayman, Boro Dropulic, Ramesh Akkina
Publikováno v:
Molecular Therapy. 24:S213
Gene-based therapies represent a promising therapeutic paradigm for the treatment of HIV, as they have the potential for sustained viral inhibition via reduced treatment interventions. One innovative approach developed here involves using conditional
Autor:
Tamson V Moore, Gina Scurti, Courtney Regan, Kelli Hutchens, Constatine Godellas, Ann Lau Clark, Kelly Moxley, Boro Dropulic, Heather Embree, Keisuke Shirai, Elizabeth Garrett-Mayer, Mingli Li, Jonathan Eby, Joseph I. Clark, Caroline Le Poole, Michael I. Nishimura
Publikováno v:
The Journal of Immunology. 196:213.5-213.5
In an open clinical trial for Stage IV melanoma patients, we are testing a promising new therapy in which the patient’s own T cells are genetically engineered with a T cell receptor (TIL 1383I TCR) targeting the melanoma antigen tyrosinase. Include
Autor:
Jonathan M. Eby, Keisuke Shirai, Kelli A. Hutchens, I. Caroline Le Poole, Elizabeth Garrett-Mayer, Joseph I. Clark, Constantine Godellas, Ann Lau Clark, Mingli Li, Michael Nishimura, Heather Embree, Courtney Regan, Boro Dropulic, Patrick J. Stiff
Publikováno v:
Journal for Immunotherapy of Cancer
Meeting abstracts Genetically engineered T cells have broadened the opportunity for use of T cell immunotherapy in cancer patients. The possibility of improving T cell efficacy via introduction of additional genes potentially gives them an advantage