Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Heather E Kleiner-Hancock"'
Autor:
Abhijit Rath, Sharon Ronald, Sanket Awate, Donard S. Dwyer, Arrigo De Benedetti, Simone N. Vigod, Floyd Galiano, J. Michael Mathis, Heather E Kleiner-Hancock, Jennifer L. Carroll
Publikováno v:
Genes & Cancer. 4:39-53
The Tousled-like kinases (TLKs) are involved in chromatin assembly, DNA repair, and transcription. Two TLK genes exist in humans, and their expression is often dysregulated in cancer. TLKs phosphorylate Asf1 and Rad9, regulating double-strand break (
Autor:
Runhua Shi, Heather E Kleiner-Hancock, Patrick Adegboyega, Jennifer N Gill, J. Michael Mathis, Zanobia Syed, Vinita Batra, John L. Clifford, Malari A. Coburn, John DiGiovanni
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research, Vol 31, Iss 1, p 57 (2012)
Journal of Experimental & Clinical Cancer Research, Vol 31, Iss 1, p 57 (2012)
The purpose of the current study was to determine whether a tropical ginger derived compound 1’-acetoxychavicol acetate (ACA), suppresses skin tumor promotion in K5.Stat3C mice. In a two-week study in which wild-type (WT) and K5.Stat3C mice were co
Autor:
Michael Mathis, Michelle Carroll-Turpin, Heather E Kleiner-Hancock, Songlin Zhang, Samuel Crooks, Allison Dugan
Publikováno v:
The FASEB Journal. 26
Protandim is a dietary supplement with potent antioxidant properties. We hypothesized that Protandim would inhibit malignant progression of ductal carcinoma in situ (DCIS). A pre-malignant human br...
Publikováno v:
International Journal of Breast Cancer, Vol 2012 (2012)
International Journal of Breast Cancer
International Journal of Breast Cancer
Auraptene is being investigated for its chemopreventive effects in many models of cancer including skin, colon, prostate, and breast. Many mechanisms of action including anti-inflammatory, antiproliferative, and antiapoptotic effects are being sugges
Autor:
Benjamin D.L. Li, Elysse A. Orchard, Heather E Kleiner-Hancock, Bing Cheng, Xiao-Lin Li, Sabrina Brueggemann, Natalia Luraguiz, Mariam A. Stoff-Khalili, Malari A. Coburn, J. Michael Mathis, Shilpa Bhatia, Yulia Maxuitenko, Songlin Zhang
Clearly new breast cancer models are necessary in developing novel therapies. To address this challenge, we examined mammary tumor formation in the Syrian hamster using the chemical carcinogen N-methyl-N-nitrosourea (MNU). A single 50 mg/kg intraperi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ee4bd75d25d506c814c858bbf5bc2cf
https://europepmc.org/articles/PMC3185182/
https://europepmc.org/articles/PMC3185182/
Autor:
Jennifer N Gill, J. Michael Mathis, Patrick Adegboyega, Angela Remeika, Runhua Shi, Heather E Kleiner-Hancock, Zanobia Syed, Misty Prince, John L. Clifford, Delira Robbins
Publikováno v:
BMC Cancer, Vol 10, Iss 1, p 394 (2010)
BMC Cancer
BMC Cancer
Background NF-κB is a survival signaling transcription factor complex involved in the malignant phenotype of many cancers, including squamous cell carcinomas (SCC). The citrus coumarin, auraptene (AUR), and the ethno-medicinal ginger (Alpinia galang
Autor:
Masayuki Yamamoto, Lisa Becks, Elysse A. Orchard, Runhua Shi, Hannah Burson, Songlin Zhang, Christopher Christophe, Heather E Kleiner-Hancock, Misty Prince, Mason Broadway, Jerry McLarty, Michael Mathis, Kevin Pruitt, Ken Itoh
Publikováno v:
BMC Cancer
BMC Cancer, Vol 10, Iss 1, p 540 (2010)
BMC Cancer, Vol 10, Iss 1, p 540 (2010)
Background Activation of nuclear factor erythroid 2-related factor (Nrf2), which belongs to the basic leucine zipper transcription factor family, is a strategy for cancer chemopreventive phytochemicals. It is an important regulator of genes induced b
Autor:
Heather E Kleiner-Hancock, Songlin Zhang, Christopher Christophe, Jerry McLarty, Misty Prince, Elysse A. Orchard, Hannah Burson, Ken Itoh, Masayuki Yamamoto, Lisa Becks
Publikováno v:
The FASEB Journal. 24
Autor:
Malari A. Coburn, Songlin Zhang, Heather E Kleiner-Hancock, Benjamin D.L. Li, Mary Lowery-Nordberg, Linda Li, James Michael Mathis, Bing Cheng
Publikováno v:
The FASEB Journal. 24
Autor:
Jesse Tubbs, Benjamin D.L. Li, Heather E Kleiner-Hancock, C. Marcelo Aldaz, Jerry McLarty, David Windler, Prasad Krishnan, Robert Grand, Karen J. Yan
Publikováno v:
BMC Cancer
BMC Cancer, Vol 9, Iss 1, p 259 (2009)
BMC Cancer, Vol 9, Iss 1, p 259 (2009)
Background Breast cancer is a major problem in the United States leading to tens of thousands of deaths each year. Although citrus auraptene suppresses cancer in numerous rodent models, its role in breast cancer prevention previously has not been rep