Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Heather Doelle"'
Autor:
Ruth McPherson, Jonathan Cohen, Heather Doelle, Sybil Hébert, Li Weng, Wendy Schackwitz, Anna Ustaszewska, Len A. Pennacchio, Nihan Kavaslar
Publikováno v:
Journal of Clinical Investigation. 115:1016-1020
Mutations in MEF2A have been implicated in an autosomal dominant form of coronary artery disease (adCAD1). In this study we sought to determine whether severe mutations in MEF2A might also explain sporadic cases of coronary artery disease (CAD). To d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19d3bf4d6cd3cf90ba5b3457c8e6c40e
https://doi.org/10.1172/jci24186
https://doi.org/10.1172/jci24186
Publikováno v:
Receptors & Clinical Investigation.
The concentration of adenosine nucleotides (ATP&ADP) in the circulation may impact health and disease by controlling cellular metabolic pathways in tissues throughout the body. Fasting plasma nucleotide levels are normally relatively low in healthy s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1000b40721693dc72cd0595e5f8cf469
https://doi.org/10.14800/rci.344
https://doi.org/10.14800/rci.344
Autor:
Sherry L. Perkins, Janice Forsythe, Heather Doelle, Eduardo Escares, Claire Pronovost, Susan Taylor-Clapp
Publikováno v:
Clinical Biochemistry. 31:67-71
To evaluate the analytical and clinical performance of the One Touch II and Advantage glucose meters for use in neonatal specimens.For the laboratory evaluation, a total of 96 umbilical cord whole blood specimens were analyzed on the One Touch II and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::066f0e039fb8a6e0ed67e791b3382d82
https://doi.org/10.1016/s0009-9120(97)00169-0
https://doi.org/10.1016/s0009-9120(97)00169-0
Autor:
Heather Doelle, Fabienne Benoist, Michael McDonnell, Ruth McPherson, Paulina Lau, Ross W. Milne
Publikováno v:
Journal of Biological Chemistry. 272:23572-23577
We have determined the role of cholesteryl ester transfer protein (CETP) in selective uptake of high density lipoprotein (HDL)-derived cholesteryl esters (CE) by human adipose tissue, using organ culture or collagenase-digested adipocytes. Incubation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbc1df3a72d7a144f42f54646c9751c9
https://doi.org/10.1074/jbc.272.38.23572
https://doi.org/10.1074/jbc.272.38.23572
A 680 kb duplication at the FTO locus in a kindred with obesity and a distinct body fat distribution
Autor:
Thet Naing, Ruth McPherson, Paulina Lau, Majid Nikpay, Robert Dent, Robert W. Davies, Heather Doelle, Mary-Ellen Harper
Common intronic SNPs in the human fat mass and obesity associated (FTO) gene are strongly associated with body mass index (BMI). In mouse models, inactivation of the Fto gene results in a lean phenotype, whereas overexpression of Fto leads to increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8a3f9059aae76e93f14d1603dc0ff6d
https://europepmc.org/articles/PMC3831078/
https://europepmc.org/articles/PMC3831078/
Autor:
Alexandre F Stewart, Ruth McPherson, Li Chen, Kathryn Williams, Heather Doelle, Robbie Davies, Sonny Dandona, Nihan Kavaslar, Julie Ruthberg, Gwen Ewart, Rosemary LaRose, Lan Vo, Yanquing Wang, Paulina Lau, Marino Labinaz, Benjamin Chow, George A Wells, Robert Roberts
Publikováno v:
Circulation. 118
Background : Coronary artery disease (CAD) is the leading cause of death in the western world. The only common genetic risk locus identified to date by us and others in genome wide association studies (GWAS) resides at 9p21.3. Methods: The Ottawa Hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca5a701d2384841867aee358f4a2d7f0
https://doi.org/10.1161/circ.118.suppl_18.s_427-a
https://doi.org/10.1161/circ.118.suppl_18.s_427-a
Autor:
Alexandre F Stewart, Ruth McPherson, Kathryn Williams, Nihan Kavaslar, Julie Rutberg, Heather Doelle, Gwen Ewart, George Wells, Robert Roberts
Publikováno v:
Circulation. 116
Purpose: To identify genes predisposing to Coronary Artery Disease (CAD). Methods: We selected the unbiased approach of using the genome wide scan association case control method. Using the Affymetrix 500K SNP array that that average a marker every 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d6eb6b1cc7e792aad2122c666d410e2
https://doi.org/10.1161/circ.116.suppl_16.ii_56
https://doi.org/10.1161/circ.116.suppl_16.ii_56
Autor:
Len A. Pennacchio, Nadav Ahituv, Robert Dent, Wendy Schackwitz, Heather Doelle, Ruth McPherson, John Michael Collier, Anna Ustaszewska, Sybil Hébert, Nihan Kavaslar
Publikováno v:
Ahituv, Nadav; Kavaslar, Nihan; Schackwitz, Wendy; Ustaszewska, Anna; Collier, John Michael; Hebert, Sybil; et al.(2005). A PYY Q62P variant linked to human obesity. Lawrence Berkeley National Laboratory. Lawrence Berkeley National Laboratory: Lawrence Berkeley National Laboratory. Retrieved from: http://www.escholarship.org/uc/item/2060q8g7
Members of the pancreatic polypeptide family and their receptors have been implicated in the control of food intake in rodents and humans. To investigate whether nucleotide changes in these candidate genes result in abnormal weight in humans, we sequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd041c24c4333110a9e936a18622c0b0
https://pubmed.ncbi.nlm.nih.gov/16368708
https://pubmed.ncbi.nlm.nih.gov/16368708
Autor:
George A. Wells, Ruth McPherson, Heather Doelle, Li Chen, Robert Roberts, Rosemary LaRose, Kathryn J.H. Williams, Melanie Belanger, Sonny Dandona, Alexandre F.R. Stewart, Olivia Assogba, Gwen Ewart
Publikováno v:
Journal of the American College of Cardiology. 53:1471-1472
To the Editor: To date, the only common genetic variant to consistently associate with risk of coronary artery disease (CAD) or myocardial infarction (MI) is the 9p21.3 variant ([1,2][1]). Several recent reports identified a SNP (rs20455) that alters
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::545be073efafd29967348188a01ef4ec
https://doi.org/10.1016/j.jacc.2008.12.051
https://doi.org/10.1016/j.jacc.2008.12.051