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of 2
pro vyhledávání: '"Heather Denning"'
Autor:
Daniel A. Peterson, Nicoletta Bivi, John H. Sloan, Robert J. Konrad, Michael E Hodsdon, Heather Denning, Thomas G. Pottanat, Matthew M. Hufford, Huy T Nguyen
Publikováno v:
Bioanalysis. 13:1113-1121
Lay abstract Measuring immunogenicity, an immune response to a drug, is important in understanding the benefits and risks associated with a drug. Immunogenicity is measured by specific tests within a laboratory; however, these tests and laboratories
Autor:
Nicoletta Bivi, Terry L. Moore, Valentina Gelfanova, Travis Shockley, Robert W. Siegel, Michael E Hodsdon, Heather Denning, George H. Rodgers, Daniel A. Peterson, Craig A. Swearingen, Robert J. Konrad, Richard E. Higgs, Boris Calderon
Publikováno v:
mAbs
Despite recent advances in the development of tools to predict immunogenicity risk of biotherapeutic molecules, the ability of a protein to elicit the formation of anti-drug antibodies (ADA) remains one of the most common causes for termination of cl